Bio-101 - Improve Research Reproducibility

Cell proliferation assay

Authors: Linhong Deng, Allen P. Liu and Mingzhi Luo
Date: Jun 29, 2022，Views：569

Original protocol used in research article：

Compression enhances invasive phenotype and matrix degradation of breast Cancer cells via Piezo1 activation
BMC Molecular and Cell Biology, Jan 3, 2022; DOI: 10.1186/s12860-021-00401-6

Study design, inclusion and exclusion criteria.

Authors: Riccardo Pofi, Elisa Giannetta, Daniele Gianfrilli and Andrea M. Isidori
Date: Jun 29, 2022，Views：544

Original protocol used in research article：

Sex-specific effects of daily tadalafil on diabetic heart kinetics in RECOGITO, a randomized, double-blind, placebo-controlled trial
Science Translational Medicine, Jun 15, 2022; DOI: 10.1126/scitranslmed.abl8503

IVDi culture

Authors: Takashi Yoshino and Katsuhiko Hayashi
Date: Jun 28, 2022，Views：600

Original protocol used in research article：

Generation of ovarian follicles from mouse pluripotent stem cells
Science, Jul 16, 2021; DOI: 10.1126/science.abe0237

Study design

Authors: Li-Huei Tsai and Ravikiran M Raju
Date: Jun 28, 2022，Views：556

Original protocol used in research article：

MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration
Science Translational Medicine, Nov 3, 2021; DOI: 10.1126/scitranslmed.abd7695

Immunostaining larval body wall neurons in Drosophila

Authors: Jacob S Jaszczak, Laura Devault, Lily Yeh Jan and Yuh Nung Jan
Date: Jun 28, 2022，Views：546

Original protocol used in research article：

Steroid hormone signaling activates thermal nociception during Drosophila peripheral nervous system development
eLife, Mar 30, 2022; DOI: 10.7554/eLife.76464

Flow cytometry

Authors: Uri T abori and Simone C Stone
Date: Jun 28, 2022，Views：531

Original protocol used in research article：

Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency
Nat Med, Jan 6, 2022; DOI: 10.1038/s41591-021-01581-6

Crystal violet biomass assays

Authors: Ana A Weil, Wai-Leung Ng and Denise Chac
Date: Jun 28, 2022，Views：606

Original protocol used in research article：

Impact of a human gut microbe on Vibrio cholerae host colonization through biofilm enhancement
eLife, Mar 28, 2022; DOI: 10.7554/eLife.73010

Western blot

Authors: Nasser M Rizk, Masoud Ghamari-Langroudi and Işın Çakır
Date: Jun 28, 2022，Views：626

Original protocol used in research article：

Sulforaphane reduces obesity by reversing leptin resistance
eLife, ; DOI: 10.7554/eLife.67368

cECG armchair

Author: Joana M. Warnecke
Date: Jun 28, 2022，Views：530

Original protocol used in research article：

Registered report protocol: Developing an artifact index for capacitive electrocardiography signals acquired with an armchair
PLoS ONE, Jul 28, 2021; DOI: 10.1371/journal.pone.0254780

Regression model of relative fitness (PyR0 model)

Authors: Fritz Obermeyer and Jacob E. Lemieux
Date: Jun 27, 2022，Views：621

Original protocol used in research article：

Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness
Science, May 24, 2022; DOI: 10.1126/science.abm1208

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