Current position
Associate Scientist I, Biochemistry Group in Biology Department, Gilead Bioscences, Foster City, CA (11/2008 to current)
Publications
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Feng, J. Y., Cheng, G., Perry, J., Barauskas, O., Xu, Y., Fenaux, M., Eng, S., Tirunagari, N., Peng, B., Yu, M., Tian, Y., Lee, Y. J., Stepan, G., Lagpacan, L. L., Jin, D., Hung, M., Ku, K. S., Han, B., Kitrinos, K., Perron, M., Birkus, G., Wong, K. A., Zhong, W., Kim, C. U., Carey, A., Cho, A. and Ray, A. S. (2014). Inhibition of hepatitis C virus replication by GS-6620, a potent C-nucleoside monophosphate prodrug. Antimicrob Agents Chemother 58(4): 1930-1942.
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Tsiang, M., Jones, G. S., Niedziela-Majka, A., Kan, E., Lansdon, E. B., Huang, W., Hung, M., Samuel, D., Novikov, N., Xu, Y., Mitchell, M., Guo, H., Babaoglu, K., Liu, X., Geleziunas, R. and Sakowicz, R. (2012). New class of HIV-1 integrase (IN) inhibitors with a dual mode of action. J Biol Chem 287(25): 21189-21203.
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Arnold, J. J., Sharma, S. D., Feng, J. Y., Ray, A. S., Smidansky, E. D., Kireeva, M. L., Cho, A., Perry, J., Vela, J. E., Park, Y., Xu, Y., Tian, Y., Babusis, D., Barauskus, O., Peterson, B. R., Gnatt, A., Kashlev, M., Zhong, W. and Cameron, C. E. (2012). Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides. PLoS Pathog 8(11): e1003030.
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Lock, M., McGorray, S., Auricchio, A., Ayuso, E., Beecham, E. J., Blouin-Tavel, V., Bosch, F., Bose, M., Byrne, B. J., Caton, T., Chiorini, J. A., Chtarto, A., Clark, K. R., Conlon, T., Darmon, C., Doria, M., Douar, A., Flotte, T. R., Francis, J. D., Francois, A., Giacca, M., Korn, M. T., Korytov, I., Leon, X., Leuchs, B., Lux, G., Melas, C., Mizukami, H., Moullier, P., Muller, M., Ozawa, K., Philipsberg, T., Poulard, K., Raupp, C., Riviere, C., Roosendaal, S. D., Samulski, R. J., Soltys, S. M., Surosky, R., Tenenbaum, L., Thomas, D. L., van Montfort, B., Veres, G., Wright, J. F., Xu, Y., Zelenaia, O., Zentilin, L. and Snyder, R. O. (2010). Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material. Hum Gene Ther 21(10): 1273-1285.
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Pulkkinen, L., Meneguzzi, G., McGrath, J. A., Xu, Y., Blanchet-Bardon, C., Ortonne, J. P., Christiano, A. M. and Uitto, J. (1997). Predominance of the recurrent mutation R635X in the LAMB3 gene in European patients with Herlitz junctional epidermolysis bullosa has implications for mutation detection strategy. J Invest Dermatol 109(2): 232-237.
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Pulkkinen, L., Kurtz, K., Xu, Y., Bruckner-Tuderman, L. and Uitto, J. (1997). Genomic organization of the integrin beta 4 gene (ITGB4): a homozygous splice-site mutation in a patient with junctional epidermolysis bullosa associated with pyloric atresia. Lab Invest 76(6): 823-833.
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Pulkkinen, L., Kimonis, V. E., Xu, Y., Spanou, E. N., McLean, W. H. and Uitto, J. (1997). Homozygous alpha6 integrin mutation in junctional epidermolysis bullosa with congenital duodenal atresia. Hum Mol Genet 6(5): 669-674.
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Christiano, A. M., Hoffman, G. G., Zhang, X., Xu, Y., Tamai, Y., Greenspan, D. S. and Uitto, J. (1997). Strategy for identification of sequence variants in COL7A1 and a novel 2-bp deletion mutation in recessive dystrophic epidermolysis bullosa. Hum Mutat 10(5): 408-414.