Education
Ph.D. in Pharmacology, Shanghai Jiao Tong University, Shanghai, China, 2013
Current position
Post-Doctoral Research Fellow, Department of Anesthesiology & Perioperative Care, University of California, Irvine (2014-present)
Publications
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Gong, N., Huang, Q., Chen, Y., Xu, M., Ma, S. and Wang, Y. X. (2014). Pain Assessment Using the Rat and Mouse Formalin Tests. Bio-protocol 4(21): e1288.
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Fan, H., Gong, N., Li, T. F., Ma, A. N., Wu, X. Y., Wang, M. W. and Wang, Y. X. (2014). Nonpeptidic GLP-1 receptor agonist WB4-24 blocks inflammatory nociception by stimulating beta-endorphin release from spinal microglia. Br J Pharmacol. (Epub ahead of print)
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Zhu, B., Gong, N., Fan, H., Peng, C. S., Ding, X. J., Jiang, Y. and Wang, Y. X. (2014). Lamiophlomis rotata, an Orally Available Tibetan Herbal Painkiller, Specifically Reduces Pain Hypersensitivity States through the Activation of Spinal Glucagon-like Peptide-1 Receptors. Anesthesiology 121(4): 835-851.
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Gong, N., Fan, H., Ma, A. N., Xiao, Q. and Wang, Y. X. (2014). Geniposide and its iridoid analogs exhibit antinociception by acting at the spinal GLP-1 receptors. Neuropharmacology 84: 31-45.
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Gong, N., Xiao, Q., Zhu, B., Zhang, C. Y., Wang, Y. C., Fan, H., Ma, A. N. and Wang, Y. X. (2014). Activation of spinal glucagon-like peptide-1 receptors specifically suppresses pain hypersensitivity. J Neurosci 34(15): 5322-5334.
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Gong, N., Li, X. Y., Xiao, Q. and Wang, Y. X. (2014). Identification of a novel spinal dorsal horn astroglial D-amino acid oxidase-hydrogen peroxide pathway involved in morphine antinociceptive tolerance. Anesthesiology 120(4): 962-975.
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Wang, Y. C., Lu, J. M., Jin, H. Z., Ma, A. N., Zhang, J. Y., Gong, N., Xiao, Q., Zhu, B., Lv, Y. F., Yu, N., Zhang, W. D. and Wang, Y. X. (2014). Beneficial effects of natural Jeju groundwaters on lipid metabolism in high-fat diet-induced hyperlipidemic rats. Nutr Res Pract 8(2): 165-171.
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Zhang, J. Y., Gong, N., Huang, J. L., Guo, L. C. and Wang, Y. X. (2013). Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., exhibits potent and specific antinociception in chronic pain by acting at spinal alpha3 glycine receptors. Pain 154(11): 2452-2462.
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Wei, H., Gong, N., Huang, J. L., Fan, H., Ma, A. N., Li, X. Y., Wang, Y. X. and Pertovaara, A. (2013). Spinal D-amino acid oxidase contributes to mechanical pain hypersensitivity induced by sleep deprivation in the rat. Pharmacol Biochem Behav 111: 30-36.
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Ma, A. N., Gong, N., Lu, J. M., Huang, J. L., Hao, B., Guo, Y., Zhong, J., Xu, Y., Chang, J. and Wang, Y. X. (2013). Local protective effects of oral 45S5 bioactive glass on gastric ulcers in experimental animals. J Mater Sci Mater Med 24(3): 803-809.
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Gong, N., Wang, Y. C., Wang, H. L., Ma, A. N., Hashimoto, K. and Wang, Y. X. (2012). Interactions of the potent D-amino acid oxidase inhibitor CBIO with morphine in pain and tolerance to analgesia. Neuropharmacology 63(3): 460-468.
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Wang, Y. X., Gong, N., Xin, Y. F., Hao, B., Zhou, X. J. and Pang, C. C. (2012). Biological implications of oxidation and unidirectional chiral inversion of D-amino acids. Curr Drug Metab 13(3): 321-331.
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Lu, J. M., Gong, N., Wang, Y. C. and Wang, Y. X. (2012). D-Amino acid oxidase-mediated increase in spinal hydrogen peroxide is mainly responsible for formalin-induced tonic pain. Br J Pharmacol 165(6): 1941-1955.
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Wei, H., Huang, J.-L., Hao, B., Wang, Y.-C., Nian, G., Ma, A.-N., Li, X.-Y., Wang, Y.-X. and Pertovaara, A. (2011). Intrathecal administration of antioxidants attenuates mechanical pain hypersensitivity induced by REM sleep deprivation in the rat. Scandinavian Journal of Pain 2(2): 64-69.
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Gong, N., Ma, A. N., Zhang, L. J., Luo, X. S., Zhang, Y. H., Xu, M. and Wang, Y. X. (2011). Site-specific PEGylation of exenatide analogues markedly improved their glucoregulatory activity. Br J Pharmacol 163(2): 399-412.
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Gong, N., Gao, Z. Y., Wang, Y. C., Li, X. Y., Huang, J. L., Hashimoto, K. and Wang, Y. X. (2011). A series of D-amino acid oxidase inhibitors specifically prevents and reverses formalin-induced tonic pain in rats. J Pharmacol Exp Ther 336(1): 282-293.
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Xin, Y. F., Li, X., Hao, B., Gong, N., Sun, W. Q., Konno, R. and Wang, Y. X. (2010). Indispensable but insufficient role of renal D-amino acid oxidase in chiral inversion of NG-nitro-D-arginine. Chem Biodivers 7(6): 1413-1423.
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Zhang, W. B., Gong, N. and Wang, Y. X. (2010). Renal SGLT2 inhibitors: a new type of oral anti-hyperglycemia drugs. Sheng Li Ke Xue Jin Zhan 41(6): 453-456.