Education
Ph.D. in Endocrinology, Institut Pasteur de Paris, France, 1993
Current position
Professor in Molecular Genetics, UFR Sciences & Techniques, University François Rabelais of Tours, France
Group leader (Transposases and Genetic Instability), UFR Pharmacie, University François Rabelais of Tours, France
Publications (since 2000)
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Bouchet, N., Jaillet, J., Gabant, G., Brillet, B., Briseno-Roa, L., Cadene, M. and Auge-Gouillou, C. (2014). cAMP protein kinase phosphorylates the Mos1 transposase and regulates its activity: evidences from mass spectrometry and biochemical analyses. Nucleic Acids Res 42(2): 1117-1128.
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Pflieger, A., Jaillet, J., Petit, A., Auge-Gouillou, C. and Renault, S. (2014). Target capture during Mos1 transposition. J Biol Chem 289(1): 100-111.
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Pflieger, A., Waffo Teguo, P., Papastamoulis, Y., Chaignepain, S., Subra, F., Munir, S., Delelis, O., Lesbats, P., Calmels, C., Andreola, M. L., Merillon, J. M., Auge-Gouillou, C. and Parissi, V. (2013). Natural stilbenoids isolated from grapevine exhibiting inhibitory effects against HIV-1 integrase and eukaryote MOS1 transposase in vitro activities. PLoS One 8(11): e81184.
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Augé-Gouillou, C. (2013). Transposons. In: Maloy and Hughes (eds). Encyclopedia of Genetics, 2nd edition. Elsevier.
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Jaillet, J., Genty, M., Cambefort, J., Rouault, J. D. and Auge-Gouillou, C. (2012). Regulation of mariner transposition: the peculiar case of Mos1. PLoS One 7(8): e43365.
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Carpentier, G., Jaillet, J., Pflieger, A., Adet, J., Renault, S. and Auge-Gouillou, C. (2011). Transposase-transposase interactions in MOS1 complexes: a biochemical approach. J Mol Biol 405(4): 892-908.
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Renault, S., Demattei, M. V., Lahouassa, H., Bigot, Y. and Auge-Gouillou, C. (2010). In vitro recombination and inverted terminal repeat binding activities of the Mcmar1 transposase. Biochemistry 49(17): 3534-3544.
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Demattei, M. V., Thomas, X., Carnus, E., Auge-Gouillou, C. and Renault, S. (2010). Site-directed integration of transgenes: transposons revisited using DNA-binding-domain technologies. Genetica 138(5): 531-540.
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Bouchet, N., Bischerour, J., Germon, S., Guillard, J., Dubernet, M., Viaud-Massuard, M. C., Delelis, O., Ryabinin, V., Bigot, Y. and Auge-Gouillou, C. (2009). First Mariner Mos1 transposase inhibitors. Mini Rev Med Chem 9(4): 431-439.
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Casteret, S., Chbab, N., Cambefort, J., Auge-Gouillou, C., Bigot, Y. and Rouleux-Bonnin, F. (2009). Physical properties of DNA components affecting the transposition efficiency of the mariner Mos1 element. Mol Genet Genomics 282(5): 531-546.
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S Germon, G Carpentier, N Bouchet and C Augé-Gouilllou. (2009) Engineering the activity of Mos1 transposase. Genetica. 137: 265-276.
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Bigot, Y., Samain, S., Auge-Gouillou, C. and Federici, B. A. (2008). Molecular evidence for the evolution of ichnoviruses from ascoviruses by symbiogenesis. BMC Evol Biol 8: 253.
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Sinzelle, L., Jegot, G., Brillet, B., Rouleux-Bonnin, F., Bigot, Y. and Auge-Gouillou, C. (2008). Factors acting on Mos1 transposition efficiency. BMC Mol Biol 9: 106.
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Brillet, B., Bigot, Y. and Auge-Gouillou, C. (2007). Assembly of the Tc1 and mariner transposition initiation complexes depends on the origins of their transposase DNA binding domains. Genetica 130(2): 105-120.
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Auge-Gouillou, C., Brillet, B., Hamelin, M. H. and Bigot, Y. (2005). Assembly of the mariner Mos1 synaptic complex. Mol Cell Biol 25(7): 2861-2870.
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Auge-Gouillou, C., Brillet, B., Germon, S., Hamelin, M. H. and Bigot, Y. (2005). Mariner Mos1 transposase dimerizes prior to ITR binding. J Mol Biol 351(1): 117-130.
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Bigot, Y., Brillet, B. and Auge-Gouillou, C. (2005). Conservation of Palindromic and Mirror Motifs within Inverted Terminal Repeats of mariner-like Elements. J Mol Biol 351(1): 108-116.
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Leroy, H., Castagnone-Sereno, P., Renault, S., Auge-Gouillou, C., Bigot, Y. and Abad, P. (2003). Characterization of Mcmar1, a mariner-like element with large inverted terminal repeats (ITRs) from the phytoparasitic nematode Meloidogyne chitwoodi. Gene 304: 35-41.
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Auge-Gouillou, C., Hamelin, M. H., Demattei, M. V., Periquet, G. and Bigot, Y. (2001). The ITR binding domain of the Mariner Mos-1 transposase. Mol Genet Genomics 265(1): 58-65.
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Auge-Gouillou, C., Hamelin, M. H., Demattei, M. V., Periquet, M. and Bigot, Y. (2001). The wild-type conformation of the Mos-1 inverted terminal repeats is suboptimal for transposition in bacteria. Mol Genet Genomics 265(1): 51-57.
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Leroy, H., Leroy, F., Auge-Gouillou, C., Castagnone-Sereno, P., Vanlerberghe-Masutti, F., Bigot, Y. and Abad, P. (2000). Identification of mariner-like elements from the root-knot nematode Meloidogyne spp. Mol Biochem Parasitol 107(2): 181-190.
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Augé-Gouillou, C., Notareschi-Leroy, H., Abad, P., Periquet, G. and Bigot, Y. (2000). Phylogenetic analysis of the functional domains of mariner-like element (MLE) transposases. Molecular and General Genetics MGG 264(4): 506-513.
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Demattei, M. V., Auge-Gouillou, C., Pollet, N., Hamelin, M. H., Meunier-Rotival, M. and Bigot, Y. (2000). Features of the mammal mar1 transposons in the human, sheep, cow, and mouse genomes and implications for their evolution. Mamm Genome 11(12): 1111-1116.