联合评审(
Andrea Puhar The Laboratory for Molecular Infection Medicine Sweden (MIMS); Umeå Centre for Microbial Research (UCMR); Department of Molecular Biology, Umea University, Sweden
44 protocols

Antoine de Morree Stanford university
33 protocols

Emmanuelle Berret Ecole Polytechnique Fédérale de Lausanne
9 protocols

Hong-guang Xia Zhejiang University
7 protocols

评审
Xuecai Ge
  • University of California, Merced
研究方向
  • 神经科学
  • 已发表 protocol 2

Education

Ph.D. in Neurobiology, Harvard University, 2009

Current position

She is a postdoc fellow in the Department of Developmental Biology at Stanford. Her research focuses on Hedgehog signaling in embryonic development and the associated diseases.

Publications

  1. Ge, X., Milenkovic, L., Suyama, K., Hartl, T., Purzner, T., Winans, A., Meyer, T. and Scott, M. P. (2015). Phosphodiesterase 4D acts downstream of Neuropilin to control Hedgehog signal transduction and the growth of medulloblastoma. Elife 4: e07068.   
  2. Frank, C. L., Ge, X., Xie, Z., Zhou, Y. and Tsai, L.-H. (2010). Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis. J Biol Chem 285(43): 33324-33337.
  3. de Anda, F. C., Meletis, K., Ge, X., Rei, D. and Tsai, L.-H. (2010). Centrosome motility is essential for initial axon formation in the neocortex. J Neurosci 30(31): 10391-10406.
  4. Singh, K. K., Ge, X., Mao, Y., Drane, L., Meletis, K., Samuels, B. A. and Tsai, L.-H. (2010). Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron 67(1): 33-48.
  5. Marin, O., Valiente, M., Ge, X. and Tsai, L. H. (2010). Guiding neuronal cell migrations. Cold Spring Harb Perspect Biol 2(2): a001834.
  6. Ge, X., Frank, C. L., Calderon de Anda, F. and Tsai, L.-H. (2010). Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis. Neuron 65(2): 191-203.
  7. Mao, Y., Ge, X., Frank, C. L., Madison, J. M., Koehler, A. N., Doud, M. K., Tassa, C., Berry, E. M., Soda, T., Singh, K. K., Biechele, T., Petryshen, T. L., Moon, R. T., Haggarty, S. J. and Tsai, L. H. (2009). Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell 136(6): 1017-1031.
  8. Rawson, J. M., Dimitroff, B., Johnson, K. G., Rawson, J. M., Ge, X., Van Vactor, D. and Selleck, S. B. (2005). The heparan sulfate proteoglycans dally-like and syndecan have distinct functions in axon guidance and visual-system assembly in drosophila. Curr Biol 15(9): 833-838.
  9. Ge, X., Hannan, F., Xie, Z., Feng, C., Tully, T., Zhou, H., Xie, Z. and Zhong, Y. (2004). Notch signaling in Drosophila long-term memory formation. Proc Natl Acad Sci U S A 101(27): 10172-10176.
已发表 protocol 2篇
In utero Electroporation of Mouse Embryo Brains
小鼠宫内胚胎脑皮层的DNA电转移

作者:Xuecai Ge日期:07/20/2012,浏览量:19514,Q&A: 1
This is a non-invasive technique to introduce transgenes into developing brains. In this technique, DNA is injected into the lateral ventricle of the embryonic brains, and is incorporated into the cells through electroporation. Embryos then continue ...
Immunofluorescence Staining on Mouse Embryonic Brain Sections
小鼠胚胎脑切片的免疫荧光染色

作者:Xuecai Ge日期:06/05/2012,浏览量:17744,Q&A: 0
This protocol comprises the entire process of immunofluorescence staining on mouse embryonic brains, starting from tissue preparation to mounting of the tissue sections.
参审 protocol 6篇
Preparation of Cerebellum Granule Neurons from Mouse or Rat Pups and Evaluation of Clostridial Neurotoxin Activity and Their Inhibitors by Western Blot and Immunohistochemistry
用老鼠或鼠仔制备小脑颗粒神经元并通过免疫印迹和免疫组织化学法评估梭菌神经毒素活性及其抑制剂
作者:Domenico Azarnia Tehran and Marco Pirazzini日期:07/05/2018,浏览量:3146,Q&A: 0
Cerebellar Granule Neurons (CGN) from post-natal rodents have been widely used as a model to study neuronal development, physiology and pathology. CGN cultured in vitro maintain the same features displayed in vivo by mature ...
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Analysis of Myosin II Minifilament Orientation at Epithelial Zonula Adherens
上皮粘着小带的微球蛋白II微丝排列分析
作者:Magdalene Michael, Xuan Liang and Guillermo A. Gomez日期:12/05/2016,浏览量:4619,Q&A: 0
Non-muscle myosin II (NMII) form bipolar filaments, which bind F-actin to exert cellular contractility during physiological processes (Vicente-Manzanares et al., 2009). Using a combinatorial approach to fluorescently label both N- and ...
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主审 protocol 39篇
Preparation and Immunofluorescence Staining of the Trachea in Drosophila Larvae and Pupae
果蝇幼虫和蛹中气管的制备和免疫荧光染色
作者:Feng Chen日期:05/05/2016,浏览量:11661,Q&A: 0
The Drosophila melanogaster trachea is a branched network of rigid chitin-lined tubes that ramify throughout the body and functions as the fly’s respiratory organ. Small openings at the ends of the tracheal tubes allow gas ...
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Isolation and Primary Cell Culture of Mouse Dorsal Root Ganglion Neurons
小鼠背根神经节神经元的分离和原代细胞培养
作者:Theresa Heinrich, Christian A. Hübner and Ingo Kurth日期:04/05/2016,浏览量:16287,Q&A: 0
We here provide a detailed protocol for the isolation and culture of primary mouse sensory neurons. The cell bodies of sensory afferent pseudounipolar neurons are located in dorsal root ganglia (DRGs) along the vertebral column. Dissected mouse DRGs ...
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