联合作者(
Christian Frezza Medical Research Council Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, UK
1 protocol

Ana S. H. Costa Medical Research Council Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, UK
1 protocol

George E. Allen Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, UK
1 protocol

Charles R. Bradshaw Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, UK
1 protocol

Magdalena Justyna Koziol
  • Gurdon Institute
研究方向
  • 分子生物学
  • 已发表 protocol 1

Education

Ph.D. from 4-year PhD programme in Developmental Biology, University of Cambridge, UK

Current position

Researcher in Gurdon Institute, University of Cambridge, UK 

Publications

  1. Koziol, M. J., Bradshaw, C. R., Allen, G. E., Costa, A. S., Frezza, C. and Gurdon, J. B. (2016). Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications. Nat Struct Mol Biol 23(1): 24-30.

  2. Koziol, M. J. and Gurdon, J. B. (2012). TCTP in development and cancer. Biochem Res Int 2012: 105203.

  3. Cabili, M. N., Trapnell, C., Goff, L., Koziol, M., Tazon-Vega, B., Regev, A. and Rinn, J. L. (2011). Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses. Genes Dev 25(18): 1915-1927.

  4. Huarte, M., Guttman, M., Feldser, D., Garber, M., Koziol, M. J., Kenzelmann-Broz, D., Khalil, A. M., Zuk, O., Amit, I., Rabani, M., Attardi, L. D., Regev, A., Lander, E. S., Jacks, T. and Rinn, J. L. (2010). A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response. Cell 142(3): 409-419.

  5. Guttman, M., Garber, M., Levin, J. Z., Donaghey, J., Robinson, J., Adiconis, X., Fan, L., Koziol, M. J., Gnirke, A., Nusbaum, C., Rinn, J. L., Lander, E. S. and Regev, A. (2010). Ab initio reconstruction of cell type-specific transcriptomes in mouse reveals the conserved multi-exonic structure of lincRNAs. Nat Biotechnol 28(5): 503-510.

  6. Koziol, M. J. and Rinn, J. L. (2010). RNA traffic control of chromatin complexes. Curr Opin Genet Dev 20(2): 142-148.

  7. Koziol, M. J., Garrett, N. and Gurdon, J. B. (2007). Tpt1 activates transcription of oct4 and nanog in transplanted somatic nuclei. Curr Biol 17(9): 801-807.

已发表 protocol 1篇
Identification of Methylated Deoxyadenosines in Genomic DNA by dA6m DNA Immunoprecipitation
通过 dA6m DNA 免疫沉淀法识别基因组DNA中的甲基化脱氧腺苷位点

作者:Magdalena J. Koziol, Charles R. Bradshaw, George E. Allen, Ana S. H. Costa and Christian Frezza日期:11/05/2016,浏览量:7453,Q&A: 0
dA6m DNA immunoprecipitation followed by deep sequencing (DIP-Seq) is a key tool in identifying and studying the genome-wide distribution of N6-methyldeoxyadenosine (dA6m). The precise function of this novel DNA ...