In the Green Lab, we are broadly interested in the fundamental molecular mechanisms governing the epigenetic regulation of the genome and its integration with cellular signaling pathways. In particular, we aim to understand how post-translational modifications of proteins regulate critical biological functions, including the establishment of proper states of gene expression and the ability of cells to respond to stress. To address our research questions, we use a diversity of approaches in molecular biology, genetics, biochemistry, genomics and proteomics in the model eukaryote Saccharomyces cerevisiae.