Amit Kumar Dey
  • Biochemist, National Institute on Aging-NIH
Research fields
  • Biochemistry, Molecular Biology, Clinical Proteomics, Mass spectrometry, bottom up proteomics
Personal information


PhD, Indian Institute of Chemical Biology, 2014

Lab information

Translational Geroproteomics Unit

Research focus

Mass spectrometry based clinical proteomics


• Dey AK, Bhattacharya S, Singh AK, Kshetrapal P, Wadhwa N, Bhatnagar S, Maitra A, F Rashid, Malakar D, Pillai MG, Salunke DM, Maiti TK, and Garbh-Ini. Carbonyl modification of plasma protein in response to cortisol level in normal pregnancy: understanding the maternal stress response. (In preparation, (#protein profiling - enrichment (Biotin-Streptavidin) of carbonylated proteins, and identification by IDA/ DDA).
• Patra R, Dey AK, and Mukherjee S. An oncogenomic trajectory study on the identification of ulcerative colitis-critical genes and their relative influence over the tumorigenesis of human colorectal carcinoma (In review).
• Saha, S., …..., Dey AK, et al. (2022) Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death. Cell Death Dis. 13, 563. https://doi.org/10.1038/s41419-022-05003-4.
• Navalkar A, ……, Dey AK, et al. (2022) Oncogenic gain of function due to p53 amyloids occurs through aberrant alteration of cell cycle and proliferation. Journal of Cell Science. 135 (15), https://doi.org/10.1242/jcs.259500.
• Kumari R, Kumar R, Dey AK, Saha S, Maiti TK (2022) S-Nitrosylation of OTUB1 Alters Its Stability and Ubc13 Binding. ACS Chem Neurosci.18;13(10):1517-1525. doi: 10.1021/acschemneuro.1c00855. Epub 2022 May 2. PMID: 35500217.
• Kumar B*, Dey AK*, Saha S, Singh AK, Thiruvengadam R, Desiraju BK, Kshetrapal P, Wadhwa N, Rashid F, Malakar D, Bhatnagar S, Salunke DM, Maiti TK, and Garbh-Ini. (2021) Dynamic alteration in vaginal secretory proteome across the early and mid-trimesters of pregnancy. Journal of Proteome Research, 20(2), 1190-1205, https://doi.org/10.1021/acs.jproteome.0c00433 *Equally contributed.
• Basak T, Dey AK, Banerjee R, Paul S, Maiti TK, and Ain R (2020). Sequestration of eIF4A by Angiomotin: a novel mechanism to restrict global protein synthesis in trophoblast cells. Stem Cells, 39(2):210-226.Doi: 10.1002/stem.3305.
• Dey AK*, Kumar B*, Singh AK, Ranjan P, Thiruvengadam R, Desiraju BK, Kshetrapal P, Wadhwa N, Bhatnagar S, Rashid F, Malakar D, Salunke DM, Maiti TK, and Garbh-Ini. (2020). Salivary proteome signatures in the early and middle stages of human pregnancy with term birth outcome. Scientific Reports 10, 8022. https://doi.org/10.1038/s41598-020-64483-6 *Equally contributed.
• Hanpude P, Bhattacharya S, Dey AK, Maiti TK (2015). Deubiquitinating enzymes in cellular signaling and disease regulation. IUBMB Life. 67(7): 544-55. DOI: 10.1002/iub.1402.
• Dey AK, Bhagat A, Chowdhury R (2013). Host Cell Contact Induces Expression of Virulence Factors and VieA, a cyclic di-GMP Phosphodiesterase in Vibrio cholerae. Journal of Bacteriology, 195 (9): 2004-10, DOI: 10.1128/JB.02127-12
• Dey AK, Bhagat A, Chowdhury R (2014). Assay for adherence of Vibrio cholerae to eukaryotic cell lines. Bio- protocol: 4(8): e1105.DOI: 10.21769/BioProtoc.1105. (This protocol was recommended by the editorial committee of Bio-protocol to be a 'featured protocol' under the field of "Microbiology")
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