XF
Editor
Xi Feng
  • Senior Scientist, Altos Labs
Research focus
  • Neuroscience
Personal information

Education

PhD, Chinese Academy of Sciences, 2011

Research focus

Reverse the aging of brain via neuron-immune crosstalk

Publications

1. Feng, X., Liu, S., Chen, D., Rosi, S. and Gupta, N. (2018) Rescue of cognitive function following fractionated brain irradiation in a novel preclinical glioma model. eLife
2. *Krukowski, K., *Feng, X., Paladini, MS., Chou, A., Sacramento, K., Gure, K., Riparip, LK., Jones, T., Campbell-Beachler, M., Nelson, G. and Rosi, S. (2018) Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits. Sci. Rep. * co-first authors
3. Feng, X., Krukowski, K., Jopson, T. and Rosi S. (2017) Delayed-matching-to-place task in a dry maze to measure spatial working memory in mice. Bio Protoc.
4. Feng, X. and Rosi, S. (2017) Targeting colony stimulating factor 1 receptor to prevent cognitive deficits induced by fractionated whole-brain irradiation. Neural Regen Res.
5. Feng, X., Jopson, T., Paladini, M.S., Liu, S., West, B., Gupta, N. and Rosi, S. (2016) CSF-1R blockade prevents fractionated cranial irradiation induced memory loss. Journal of Neuroinflammation.
6. Feng, X., Szulzewsky, F., Yerevanian A., Chen Z., Heinzmann D., Rasmussen, D.R, Alvarez-Garcia, V., Kim, Y., Wang, B., Tamagno, I., Zhou, H., Li, X., Kettenmann, H., Ransohoff, R.M. and Hambardzumyan, D. (2015) Loss of CX3CR1 increases accumulation of inflammatory monocytes and promote gliomagenesis. Oncotarget.
7. Feng, X., Liu, X., Zhang, W., and Xiao, W. (2011) P53 Directly Suppresses BNIP3 Expression to Protect Against Hypoxia-induced Cell Death. EMBO Journal.
8. Krukowski, K., Chou, A., Feng, X., Tiret, B., Paladini, M.S., Riparip, L.K., Chaumeil, M.M., Lemere, C and Rosi, S. (2018) Traumatic Brain Injury in Aged Mice Induces Chronic Microglia Activation, Synapse Loss, and Complement-Dependent Memory Deficits. Int. J. Mol. Sci.
9. Guglielmetti, C., Chou, A., Krukowski, K., Najac, C., Feng, X.,Riparip, L.R., Rosi, S., Chaumeil M.M., (2017) In vivo metabolic imaging of Traumatic Brain Injury. Scientific Reports.
10. Chen, Z., Feng, X., Herting, C.J., Alvares Garcia, V., Nie, K., Pong, W.W., Rasmussen, R., Dwivedi, B., Seby, S., Wolf, S.A., Gutmann, D., and Hambardzumyan, D. (2017) Identity and gene profile of tumor-associated macrophages in glioblastoma. Cancer Research
11. Szulzewsky, F., Pelz, A., Feng, X., Synowitz, M., Markovic, D., Langmann, T., Holtman, I.R., Wang, X., Eggen, B.J.L., Boddeke, H., Hambardzumyan, D., Wolf, S.A. and Ketternmann, H. (2015) Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and higly express GPNMB and SPP1. PLoS One.
12. Pitter, K.L.,Tamagno, I., Feng, X., Ghosal, K., Amankulor, N., Holland, E.C., and Hambardzumyan, D. (2014) The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions. Glia.
13. Hu, B., Zhang, W., Feng, X., Ji, W., Xie, X., and Xiao, W. (2014) Zebrafish eaf1 Suppresses Foxo3b Expression to Modulate Transcriptional Activity of Gata1 and Spi1 in Primitive Hematopoiesis. Developmental Biology.
14. Pong, W., Walker, J., Wylie, T., Magrini, V., Luo, J., Emnett, R., Choi, J., Cooper, M., Griffith, M.,Griffith, O., Rubin, J., Fuller, G., Piwnica-Worms, D., Feng, X., Hanbardzumyan, D., DiPersio, J., Mardis, J.,and Gutmann, D. (2013) F11R is a Novel Monocyte Prognostic Biomarker for Malignant Glioma. PLOS ONE.
15. Li, M., He, Y., Feng, X., and Huang, J. (2012) Genome-wide stidies of the transcriptional regulation by p53. Biochimica et Biophysica Acta.
16. Wan, X.,Hu, B., Liu, J.,Feng, X., and Xiao, W., (2011) The Essential Role of Mll in Zebrafish Hematopoiesis. Journal of Biological Chemistry.
17. Zhou, J., Feng, X., Ban, B., Liu, J., Wang, Z., and Xiao, W. (2009) The Elongation Factor Ell (Eleven-nineteen Lysine-Rich Leukemia) Acts as a Transcription Factor for Direct Thrombospondin-1 Regulation. Journal of Biological Chemistry.
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