Robert Grant Gladstone Institutes, University of California (UCSF), USA
1 protocol

Mekhala Maiti Gladstone Institutes, University of California (UCSF), USA
1 protocol

Marianne Gesner Gladstone Institutes, University of California (UCSF), USA
1 protocol

Warner Greene GIVI, Gladstone Institute, USA
1 protocol
Alka Mehra Institute of Genomics and Integrative Biology
45 protocols

Balasubramanian Venkatakrishnan Syngene International Limited
3 protocols

Daniela Boehm Gladstone Institute of Virology and Immunology
3 protocols

Ivan Zanoni Harvard Medical School
78 protocols

Marielle Cavrois
  • Faculty, Gladstone Institutes and University of California, San Francisco
Research focus
  • Cell biology
  • HIV, entry, fusion, envelop, replication, dendritic cells
  • 2 Author merit


PhD, University of Lille, France

Lab information

Marielle Cavrois


Selected 5 publications

Cavrois M, de Noronha C, Greene WC (2002) A sensitive and specific enzyme-based assay detecting HIV-1 virion fusion in primary T lymphocytes. Nature Biotechnology, 11:1151–1154.
Cavrois M, Neidleman J, Kreisberg JF, Fenard D, Callebaut C, Greene WC (2006) HIV fusion to dendritic cells declines as cells mature. Journal of Virology, 80:1992–1999.
Cavrois M, Neidleman J, Greene WC (2007). In vitro derived dendritic cells trans-infect CD4 T cells primarily with surface-bound HIV-1 Virions. PLoS Pathogens, 3:e4.
Marielle Cavrois, Jason Neidleman, Mario L. Santiago, Cynthia A. Derdeyn, Eric Hunter, and Warner C. Greene. Enhanced Fusion and Virion Incorporation for HIV-1 Subtype C Envelope Glycoproteins with Compact V1/V2 Domains. Journal of Virology, 88:2083–2094, 2014. PMCID: PMC3911571
Cavrois M, Banerjee T, Mukherjee G, Raman N, Hussien R, Rodriguez BA, Vasquez J, Spitzer MH, Lazarus NH, Jones JJ, Ochsenbauer C, McCune JM, Butcher EC, Arvin AM, Sen N, Greene WC, Roan NR. (2017) Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells. Cell Reports. 20(4):984–998.
2 Protocols published
Fluorescence-linked Antigen Quantification (FLAQ) Assay for Fast Quantification of HIV-1 p24Gag
Authors:  Marianne Gesner, Mekhala Maiti, Robert Grant and Marielle Cavrois, date: 12/20/2014, view: 10180, Q&A: 1
The fluorescence-linked antigen quantification (FLAQ) assay allows a fast quantification of HIV-1 p24Gag antigen. Viral supernatant are lysed and incubated with polystyrene microspheres coated with polyclonal antibodies against HIV-1 p24 ...
HIV-1 Fusion Assay
Authors:  Marielle Cavrois, Jason Neidleman and Warner C. Greene, date: 08/20/2014, view: 14462, Q&A: 0
The HIV-1 fusion assay measures all steps in the HIV-1 life cycle up to and including viral fusion. It relies on the incorporation of a β-lactamase–Vpr (BlaM-Vpr) protein chimera into the virion and the subsequent transfer of this chimera into the ...
5 Protocols reviewed
A Bioreactor Method to Generate High-titer, Genetically Stable, Clinical-isolate Human Cytomegalovirus
Human cytomegalovirus (HCMV) infection is a major cause of morbidity and mortality in transplant patients and a leading cause of congenital birth defects (Saint Louis, 2016). Vaccination and therapeutic studies often require scalable cell culture ...
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Transient Transfection-based Fusion Assay for Viral Proteins
Authors:  Melina Vallbracht, Christina Schröter, Barbara G. Klupp and Thomas C. Mettenleiter, date: 03/05/2017, view: 10099, Q&A: 1
Membrane fusion is vital for entry of enveloped viruses into host cells as well as for direct viral cell-to-cell spread. To understand the fusion mechanism in more detail, we use an infection free system whereby fusion can be induced by a minimal ...
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2 Protocols edited
Analysis of Early Phase HIV-1 Replication and Integration Events by Using Real-time PCR
Authors:  Graf Laura, Steven P. Moran, Sally Ro, Carlos M.C. de Noronha and Binshan Shi, date: 02/20/2019, view: 4293, Q&A: 0
Upon entry into a host cell, the HIV-1 virus undergoes a series of critical early replication events including reverse transcription, nuclear import, and integration of its cDNA into the host genome. Molecular assays used to detect and analyze ...
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HIVGKO: A Tool to Assess HIV-1 Latency Reversal Agents in Human Primary CD4+ T Cells
Authors:  Emilie Battivelli and Eric Verdin, date: 10/20/2018, view: 5743, Q&A: 0
While able to suppress HIV replication in HIV infected individuals, combination antiretroviral therapy (ART) fails to eliminate viral latent reservoir, which consists in integrated transcriptional silenced HIV provirus. So far, identification of ...
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