Issued Patents and Published Patent Applications
Koerber, J. T., Lee, W. P., Yi, T., Zhang, J., Austin, C. D., Chiu, C. P. C., Chavarria-Smith, J. E., & Sudhamsu, J. (2025). Anti-KLK7 antibodies, anti-KLK5 antibodies, multispecific anti-KLK5/KLK7 antibodies, and methods of use. U.S. Patent Nos. 12,312,414 and 12,312,415. Issued May 27, 2025. Also published as U.S. Patent App. No. 20260035481. Published Feb 5, 2026.
Austin, C. D., Lawrence, D. A., & Ashkenazi, A. (2012). Methods and materials for observing apoptosis. U.S. Patent No. 8,198,033. Issued June 12, 2012.

Peer Reviewed Publications
Chan, C., Chang, P., Chalasani, S., Tao, J., Raghu, H., and Austin, C.D. Resolving the Renal Microenvironment: A 5-Plex Immunofluorescence Workflow to Quantify B-lineage Cells in FFPE Lupus Nephritis Biopsies. Frontiers in Immunology (in press) 2026.
Tleugabulova, M.C., Carlos, S.M., Wong, A., Arlantico, A., Liu, M., Webster, J., Austin, C.D., Korin, B., Avraham, S., Lund, J., Jeet, S., Reiss, A., Modrusan, Z., Has Brightbill, H., Durinck, S., Diamond, M.S., Shaw, A.S., & Nitschké. Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade. Nature Communications) 6;15(1):9575, 2024.
Marchi, E., Hinks, T.S.C., Richardson, M, Khalfaoui, L., Symon, F.A., Rajasekar, P., Clifford, R., Hargadon, B., Austin, C.D., MacIsaac, J.L., Kobor, M.S., Siddiqui, S., Mar, J.S., Arron, J. R, Choy, D.F., Bradding, P. The effects of inhaled corticosteroids on healthy airways. Allergy, 00:1–13, https://onlinelibrary.wiley.com/doi/10.1111/all.16146, 2024
Looney, C.M., Schroeder, A., Tavares, E., Garg, J., Schindler, T., Vincenti, F., Redfield, R., Jordan, S., Busque, S., Woodlke, E., Khan, J., Eastham, J., Micallef, S., Austin, C.D., and Morimoto, A. Obinutuzumab Effectively Depletes Key B-cell Subsets in Blood and Tissue in End-stage Renal Disease Patients Transplantation Direct 9(2):e1436 2023.
Chavarria-Smith, J., Chiu, C.P.C., Jackman, J., Yin, P., Zhang, J., Hackney, J., Sun, Y., Tao, J., Dunlap, D., Ghodge, S., Lin, W.Y., Li, H., Hernandez-Barry, H., Loyet, K., Chen, E., Liu, J., Tyagi, T., Tam, C., Wu, J., Yaspan, B. L., Cai, H., Balazs, M., Arron, J.L., Li, J., Lazarus, R.A., Austin, C.D., Lee, W.P., Sudhamsu, J., Koerber, J.T., Yi, T. Combined inhibition of KLK5 and KLK7 with monoclonal antibodies ameliorate disease in experimental models of Netherton Syndrome and atopic dermatitis. Science Translational Medicine. 14(675):eabp91, 1-16; 2022.
Huang, K., Pantua, H., Diao, J., Skippington, E., Volny, M., Sandoval, W., Tikku, V., Peng, Y., Sagolla, M., Noland, C.L., Yan, D., Kang, J., Katakam, A.K., Payandeh, J., Reichelt, M., Tan, M.W., Austin, C.D., Hanan, E., Xu, M., and Kapadia, S.B. Deletion of a novel lipoprotein confers resistance to inhibitors of type II signal peptidase in Acinetobacter baumannii. Proc Natl Acad Sci U S A. 119(38): e2123117119, 2022.
Khalfaoui, L., Symon, F.A., Couillard, S., Hargadon, B., Chaudhuri, R., Bicknell, S., Mansur, A.H., Shrimanker, R., Hinks, T.S.C., Pavord, I.D., Fowler, S.J., Brown, V., McGarvey, L.P., Heaney, L.G., Austin, C.D., Howarth, P.H., Arron, J.R., Choy, D.F., Bradding, P., Airway remodeling rather than cellular infiltration characterizes both type2 cytokine biomarker-high and -low severe asthma. Asthma, 00:1-13 (https://doi.org/10.1111/all.15376), 2022.
Guidi, R., Xu, D., Choy, D., Ramalingam, T., Lee, W., Modrusan, Z., Liang, Y., Marsters, S., Ashkenazi, A., Huynh, A., Mills, J., Flanagan, S., Hambro, S., Nunez, V., Austin, C.D., Cao, Y., Clarke, C., Panettieri, Jr., R., Koziol-White, C., Jester, W., Wang, F., Wilson, M.S. Steroid-induced Fibroblast Growth Factors (FGFs) orchestrate an Epithelial-Mesenchymal Inflammatory axis in Severe Asthma. Science Translational Medicine. 14(641):eabl8146, 1-17; 2022.
Verma, V., Wang, L., Labadie, S., Liang, J., Sellers, B., Wang, J., Dong, L., Wang, Q., Zhang, S., Xu, Z., Zhang, Y., Niu, Y., Wang, X., Wai, J., Koehler, M., Hu, H., Alexander, M.K., Nishiyama, M., Miu, A., Xu, Y., Pang, J., Katakam, A.K., Reichelt, M., Austin, C.D., Ho, H., Payandeh, J., Koth, C. Discovery of Inhibitors of the LPS transporter MsbA: From a Screening Hit to Potent Wild-Type Gram-negative Activity. Journal of Medicinal Chemistry, 65(5):4085–4120, 2022.
Headland, S.E., Dengler, Xu, H.S.D., Teng, G., Everett, C., Ratsimandresy, R.A., Yan, D., Ganeshan, K., Nazarova, E., Gierke, S., Wedeles, C.J., Guidi, R., DePianto, D.J., Morshead, K.B., Huynh, A., Mills, J., Flanagan, S., Hambro, S., Nunez, V., Klementowicz, J.E., Shi, Y., Wang, J., Bevers 3rd, J., Ramirez-Carrozzi, V., Pappu, R., Abbas, A., Vander-Heiden, J., Choy, D.F., Yadav, R., Modrusan, Z., Panettieri Jr., R.A., Koziol-White, C., Jester Jr., W.F., Jenkins, B.J., Cao, Y., Clarke, C., Austin, C.D., Lafkas, D., Xu, M., Wolters, P.J., Arron, J.R., West, N.R., and Wilson, M.S. Oncostatin M translates bacterial triggers into airway inflammatory and mucus-secreting responses in severe asthma. Science Translational Medicine 14(627):eabf8188, 1-15, 2022.
Diao, J., Komura, R., Sano, T., Pantua, H., Storek, K.M., Inaba, H., Ogawa, H., Noland, C.L., Peng, Y., Gloor, S.L., Yan, D., Kang, J., Katakam, A.K., Volny. M., Liu, P., Nickerson, N.N., Sandoval, W., Austin, C.D., Murray, J., Rutherford, S.T., Reichelt, M., Xu, Y., Xu, M., Yanagida, H., Nishikawa, J., Reid, P.C., Cunningham, C.N., and Kapadia, S.B. Inhibition of Escherichia coli lipoprotein diacylglyceryl transferase is insensitive to resistance caused by deletion of Braun’s lipoprotein. J. Bacteriology 203(13):e00149-21, 1-20, 2021.
Entwistle, L.J., Aegerter, H., Czieso, S., Amaniti, E., Guidui, R., Sesay, A., Nikolov, N., Chakravarty, P., Huynh, A., Mills, J., Flanagan, S., Hambro, S., Nunez, V., Cao, Y., Clarke, C., Martzell, A., Leong, L., Mills, J., Austin, C.D., and Wilson, M.S. Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising Type-2 memory responses in the intestine following helminth infection. Mucosal Immunol 14(4):912-922, 2021.
Balestrini, A., Joseph, V., Dourado, M., Reese, R.M., Shields, S.D., Rougé, L., Bravo, D.D., Chernov-Rogan, T., Austin, C.D., Chen, H., Wang, L., Villemure, E., Shore, D.G.M., Verma, V.A., Hu, B., Chen, Y., Leong, L., Bjornson, C., Hotzel, K., Gogineni, A., Lee, W.P., Suto, E., Wu, X., Liu, J., Zhang, J., Gandham, V., Wang, J., Payandeh, J., Ciferri, C., Estevez, A., Arthur, C.P., Kortmann, J., Wong, R.L., Heredia, J.E., Doerr, Jung, M., Vander Heiden, J.A., Roose-Girma, M., Tam, L., Barck, K.H., Carano, R.A.D., Ding, H.T., Brillantes, B., Tam, C., Yang, X., Gao, S.S., Ly, J.Q., Liu, L., Chen, L., Liederer, B.M., Lin, J.H., Magnuson, S., Chen, J., Hackos, D.H., Elstrott, J., Rohou, A., Safina, B.S., Volgraf, M., Bauer, R.N., and Riol-Blanco, L. A TRPA1 Inhibitor Suppresses Neurogenic Inflammation and Smooth Muscle Contraction for the Treatment of Asthma. JEM, 218(4):e20201637, 2021.
Katewa, A, Suto, E., Hui J., Heredia, J., Liang, J., Hackney, J., Anderson, K., Alcantar, T., Bacarro, N., Dunlap, D., Eastham-Anderson, J., Martinez, A.P., Rairdan, X.Y., Modrusan, Z., Lee, W.P., Austin, C.D., Lafkas, D., and Ghilardi, N. The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models. PLOS ONE, 16(1):e0244439. 2021.
Austin, C.D., Edick, M.G., Ferrando, R.E., Solon, M., Baca, M., Mesh, K., Bradding, P., Gauvreau, G.M., Sumino, K., FitzGerald, J.M., Israel, E., Bjermer, L., Bourdin, A., Arron, J.R., Choy, D.F., Olsson, J.K., Abreu, F., Howard, M., Wong, K., Cai, F., Peng, K., Putnam, W.S., Holweg, C.T.J., Matthews, J.G., Kraft, and M., Woodruff, P.G. A randomized, placebo-controlled trial evaluating effects of lebrikizumab on airway eosinophilic inflammation and remodeling in uncontrolled asthma (CLAVIER). Clin Exp Allergy, 50(12):1342-1351, 2020.
Pantua, H., Skippington, E., Braun, M., Noland, C., Diao, J., Peng, C.Y., Gloor, S., Yan, D., Kang, J., Katakam, A.K., Reeder, J., Castanedo, G., Garland, K., Komuves, L., Sagolla, M., Austin, C.D., Murray, J., Xu, Y., Modrusan, Z., Xu, M., Hanan, E., Kapadia, S.B. Unstable mechanisms of resistance to inhibitors of Escherichia coli lipoprotein signal peptidase. MBio, 11(5):e02018-20, 2020.
Corzo, C.A., Varfolomeev, E., Francesca Setiadi, A., Francis, R., Klabunde, S., Senger, K., Sujatha-Bhaskar, S., Drobnick, J., Suto, E., Huang, Z., Eastham-Anderson, J., Katewa, A., Pang, J., Domeyer, M., Dela Cruz, C., Paler-Martinez, A., Lau, V.W.C., Hadadianpour, A., Ramirez-Carrozi, V., Sun, Y., Bao, K., Xu, D., Hunley, E., Brightbil, H.D., Warming, S., Roose-Girma, M., Wong, A., Tam, L., Emson, C., Bryan, M.C., Do, S., Crawford, J.J., Young, W.B., McKenzie, B.S., Asghari, V., Vucic, D., Hackney, J.A., Austin, C.D., Lee, W.P., Lekkerkerker, A., Kiefer, J.R., Townsend, M.J., and Zarrin, A.A. IRAK4 kinase activity positively regulates both endosomal TLR and immune complex signaling in immune cells. Sci Signal. 13(634):eaaz1053, 2020
Maun, H.R., Jackman, J., Choy, D.F., Loyet, K.M., Staton, T.L., Jia, G., Dressen, A., Hackney, J.A, Bremer, M., Walters, B.T., Vij, R., Chen, X., Trivedi, N.N, Morando, A., Lipari, M.T., Franke, Y., Wu, X., Zhang, J., Liu, J., Wu, P., Chang, D., Guerra, L.O., Christensen, E., Wong, M., Corpuz, R., Hang, J.Q., Lutman, J., Sukumaran, S., Wu, Y., Ubhayakar, S., Liang, X., Schwartz, L.B., Babina, M., Woodruff, P.G., Fahy, J.V., Ahuja, R., Caughey, G.H., Kusi, A., Dennis, M.S., Eigenbrot, C., Kirchhofer, D., Austin, C.D., Wu, L.C., Koerber, J.T., Lee, W.P., Yaspan, B.L., Alatsis, K.R., Arron, J.R., Lazarus, R.A., Yi, T. An allosteric anti-tryptase antibody for the treatment of mast cell-mediated severe asthma. Cell 179(2), 417-431.e19, 2019.
Lin, W., Xu, D., DeVoss, J., Austin, C.D., Caplazi, P., Senger, K., Sun, Y., Jeet, S., Young, J., Delarosa, D., Suto, E., Huang, Z., Zhang, J., Yan, D., Corzo, C., Barck, K., Rajan, S., Looney, C., Gandham, V., Lesch, J., Liang, W., Nakamura, G., Mai, E., Ngu, H., Ratti, N., Chen Y., Misner, D., Lin, T., Danilenko, D., Katavolos, P., Doudemont, E., Uppal, H., Eastham-Anderson, J., Mak, J., de Almeida, P.E., Bao, K., Hadadianpour, A., Keir, M., Carano, R., Diehl, L., Xu, M., Wu, Y., Weimer, R.M., DeVoss, J., Lee, W.P., Balazs, M., Walsh, K., Alatsis, K.R., Martin, F., and Zarrin, A.A. Function of CSF1 and IL34 in macrophage homeostasis, inflammation and cancer. Front. Immunol., 04 September (https://doi.org/10.3389/fimmu.2019.02019), 2019.
Siddiqui, S., Shikotra, A., Richardson, M., Doran, E., Choy, D., Bell, A., Austin, C.D., Eastham-Anderson, J., Hargadon, B., Arron, J.R., Wardlaw, A., Brightling, C.E., Heaney, L.G., Gorban, A., and Bradding, P. Airway Pathological Heterogeneity in Asthma: Visualization of Disease Microclusters using Topological Data Analysis. J Allergy Clin Immunol, 142(5), 1457–1468, 2018.
Ho, H., Miu, A., Alexander, M.K., Garcia, N.K., Oh, A., Zilberleyb, I., Reichelt, M., Austin, C.D., Tam, C., Shriver, S., Hu, H., Labadie, S.S., Liang, J., Wang, L., Wang, J., Lu, Y., Purkey, H.E., Quinn, J., Franke, Y., Clark, K., Beresini, M.H., Tan, M.-W., Sellers, B.D., Maurer, T., Koehler, M., Wecksler, A.T., Kiefer, J.R., Verma, V., Xu, Y., Nishiyama, M., Payandeh, J., and Koth, C.M. Structural basis for dual-mode inhibition of the ABC transporter MsbA. Nature 557, 196–201, 2018.
Brightbill, H.D., Suto, E., Blaquiere, N., Ramamoorthi, N., Sujatha-Bhaskar, S., Gogol, E.B., Castanedo, G.M., Jackson, B.T., Kwon, Y.C., Haller, S., Lesch, J., Bents, K., Everett, C., Kohli, P.B., Linge, S., Christian, L., Barrett, K., Jaochico, A., Berezhkovskiy, L.M., Fan, P.W., Modrusan, Z., Veliz, K., Townsend, M.J., DeVoss, J., Johnson, A.R., Godeman, R., Lee, W.P., Austin, C.D., McKenzie, B.S., Hackney, J.A., Crawford, J.J., Staben, S.T., Ismaili, M.H.A., Wu, L.C., and Ghilardi, N. NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus. Nat. Commun, 9(1):179, 2018.
Lopez, M.S., Kang, J., Yan, D., McCreary, M., Modrusan, Z., Austin, C.D., Xu, M., and Brown, E.J. Host-derived fatty acids activate Type VII secretion in Staphylococcus aureus. Proc Natl Acad Sci U S A., 114(42):11223-11228, 2017.
Sitrin, J., Suto, E., Wuster, A., Eastham-Anderson, J., Kim, J., Austin, C.D., Lee, W.P., and Behrens, T.W. The Ox40/Ox40 Ligand Pathway Promotes Pathogenic Th Cell Responses, Plasmablast Accumulation, and Lupus Nephritis in NZB/W F1 Mice. J. Immunol, 199(4):1238-1249, 2017.
Diao, J., Bouwman, C. Yan, D., Kang, J., Katakam, A.K., Liu, P., Pantua, H., Abbas, A. Nickerson, N. Austin, C.D., Reichelt, M., Sandoval, W., Xu, M., Whitfield, C., and Kapadia, S. Peptidoglycan association of murein lipoprotein is required for KpsD-dependent group 2 capsular polysaccharide expression and serum resistance in a uropathogenic Escherichia coli isolate. MBio, 8(3):e00603-17), 2017
Katewa, A., Wang, Y., Hackney, J. A., Huang, T., Suto, E., Ramamoorthi, N., Austin, C. D., Bremer, M., Chen, J. Z., Crawford, J. J., Currie, K. S., Blomgren, P., DeVoss, J., DiPaolo, J. A., Hau, J., Johnson, A., Lesch, J., DeForge, L. E., Lin, Z., Liimatta, M., Lubach, J. W., McVay, S., Modrusan, Z., Nguyen, A., Poon, C., Wang, J., Liu, L., Lee, W. P., Wong, H., Young, W. B., Townsend, M. J., and Reif, K. Btk-specific inhibition blocks pathogenic plasma cell signatures and myeloid cell-associated damage in IFNα-driven lupus nephritis. JCI Insight, 2(7), e90111, 2017.
Ramirez-Carrozzi, V., Sambandam, A., Zhou, M., Yan, D., Kang, J., Wu, X., Suto, E., Baca, M., Austin, C., Xu, M., Lee, W., and Pappu, R. Combined blockade of the IL13 and IL33 pathways leads to a greater inhibition of Type-2 inflammation over inhibition of either pathway alone. J Allergy Clin Immunol., 139(2):705-708e6, 2017.
Kofoed, E.M., Yun, D., Katakam, A.K., Reichelt, M., Lin, B.,Kim, J., Park, S., Date, S., Xu, M., Austin, C.D., Mauer, T., and Tan, M-W. De novo guanine biosynthesis, but not the riboswitch-regulated purine salvage pathway, is required for Staphylococcus aureus infection in vivo. J. Bacteriology, 198(14):2001-2015, 2016.
Rajapaksa, K.S., Huang, T., Sharma, N., Lui, S., Solon, M., Reyes, A., Paul, S., Yee, A., Tao, J., Chalasani, S., Bien-Ly, N., Barck, K., Carano, R.D., Wng, J., Rangell, L., Bremer, M., Danilenko, D.M., Katavolos, P., Hotzel, K., Reif, K., and Austin, C.D. Preclinical safety profile of a depleting antibody against CRTh2 for asthma: Well tolerated despite unexpected CRTh2 expression on vascular pericytes in the central nervous system and gastric mucosa. Toxicol Sci., 152(1):72-84, 2016.
Huang, T., Hazen, M., Shang, Y., Zhou, M., Wu, X., Yan, D., Lin, Z., Solon, M., Lius, E., Hgu, H., Shi, Y., Katewa, A., Choy, D.F., Ramamoorthi, N., Castellanos, E.R., Balazs, M., Xu, M., Lee, W.P., Matsumoto, M.L., Payandeh, J., Arron, J.R., Hongo, J., Wang, J., Hötzel, I., Austin, C.D., and Reif, K. Depletion of major pathogenic cells in asthma by targeting the CRTh2. JCI Insight 1(7):e86689, 2016.
Katakam, A.K., Brightbill, H.D., Franci, C., Kung, C., Asghari, V., Wu, L., Mellman, I, Delamarre, L., and Austin, C.D. Dendritic cells require NIK for CD40-dependent antigen cross-priming of CD8+ T cells. Proc Natl Acad Sci U S A., 112(47):14664-14669, 2015.
Sun, Y., Peng, I., Webster, J.D., Suto, E., Lesch, J., Wu, X., Senger, K., Francis, G., Barrett, K., Collier, J.L., Burch, J.D., Zhou, M., Chen, Y., Chan, C., Eastham-Anderson, J., Ngu, H., Li, O., Staton, T., Havnar, C., Jaochico, A., Jackman, J., Jeet, S., Riol-Blanco, L., Wu, L., Choy, D.F., Arron, J.R., McKenzie, B., Ghilardi, N., Hicham, M., Ismali, A., Pei, Z., DeVoss, J., Austin, C.D., Lee, W.P., and Zarrin, A.A. Inhibition of the kinase ITK in a mouse model of asthma reduces cell death and fails to inhibit the inflammatory response. Science Signaling 8(405):ra122, 2015.
Lafkas, D., Shelton, A., Chiu, C., de Leon, G.P., Chen, Y., Stawicki, S., Siltanen, C., Reichelt, M., Zhou, M., Wu, X., Eastham-Anderson, J., Moore, H., Roose-Girma, M., Chinn, Y., Hang, J.Q., Warming, S., Egen, J., Lee, W.P., Austin, C., Wu, Y., Payandeh, J., Lowe, J.B., and Siebel, C.W. Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung. Nature, 528(7580):127-131, 2015.
Brightbill H.D., Jackman J., Suto E., Kennedy H., Jones C., Chalasani S., Lin Z., Tam L., Roose-Girma M., Balazs M., Austin C.D., Lee W.P., and Wu, L.C. Condition deletion of NF-κB-inducing kinase (NIK) in adult mice disrupts mature B cell survival and activation. J. Immunol 195(3):953-964, 2015.
Misaghi, S., Senger, K., Sai, T., Qu, Y., Sun, Y., Hamidzadeh, K., Nguyen, A., Jin, Z., Zhou, M., Yan, D., Lin, W., Lin, Z., Lorenzo, M., Sebrell, A., Ding, J., Xu, M., Caplazi, P., Austin, C.D., Balazs, M., Roose-Girma, M., DeForge, L., Warming, S., Lee, W.P., Dixit, V.M., and Zarrin, A.A. A polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination. Proc Natl Acad Sci U S A. 110(39):15770-15775, 2013.
Auerbach, M., Yan, D., Fouts, A, Xu, M., Esteves, A., Austin, C.D., Bazan, F., and Feierbach, B. Characterization of the guinea pig CMV gH/gL/GP129/GP131/GP133 complex in infection and spread. Virology, 441:75-84, 2013.
Lo, B., Strasser, G., Sagolia, M., Austin, C.D., Juntilla, M., and Mellman, I. Chemical genetics ex vivo reveals that Lkb1/Par4 regulates mammalian organogenesis along AMPK-dependent and -independent pathways. J. Cell Biol 199:1117-1130, 2012.
Watkins B.Y., Joshi, S.A., Ball D.A., Leggett, H., Park, S., Kim, J., Austin, C.D., Paler-Martinez, A., Xu, M., Downing, K.H., and Brown, E.J. Mycobacterium marinum SecA2 promotes stable granulomas and induces TNF-α in vivo. Infect. Immun, 80(10):3512-3520, 2012.
Talay, O., Yan, D., Brightbill1, H.D., Straney, E.E.M., Ladi, E., Egen, J.G., Austin, C.D., Xu, M., and Wu, L.C. Direct detection of IgE-switched B cells in an IgE-GFP reporter mouse reveals a germinal center pathway for the generation of IgE memory B cells and plasma cells. Nat Immunol, 13(4):396-404, 2012.
Chou, M.Y., Austin, C.D., and Kim, J.M. Collective Action of Hematopoeitic Cell Subsets Mediate Anti-IL10R1 and CpG Tumor Immunity. Cancer Immunol Immunother, 61(7):1055-1064, 2012.
Shikotra, A., Choy, D.F., Ohri, C.M., Doran, E., Butler, C., Hargadon, B., Shelley, M., Abbas, A.R., Austin, C.D., Jackman, J., Wu,L.C., Heaney, L.C., Arron, J.R., and Bradding, P. Increased expression of immunoreactive thymic stromal lymphopoetin in severe asthma. J Allergy Clin Immunol, 129(1):104-11,e1-9, 2011.
Seshasayee, D., Lee, W.P., Zhou, M., Shu, J., Suto, E., Zhang, J., Diehl, L., Meng, Y.G., Tan, M., Austin, C.D., Bullens, S.L., Seeber, S., Fuentes, M.E., Labrijn, A.F., Graus, Y.M.F., Miller, L.A., Schelegle, E.S., Hyde, D.M., Wu, L.G., Hymowitz, S.G., and Martin, F. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven apoptotic inflammation. J. Clin. Invest. 117(12):3868-78, 2007.
Austin, C.D., Lawrence, D.A., Peden, A.A., Varfolomeev, E.E., Totpal, K., De Maziere, A.M., Klumperman, J., Arnott, D., Pham, V., Scheller, R.H., and Ashkenazi, A. Death-receptor activation halts clathrin-dependent endocytosis. Proc Natl Acad Sci U S A. 103(27):10283-88, 2006.
Austin, C.D., Wen, P, Gazzard, L., Nelson, C., Scheller, R.H., and Scales, S. Intracellular reduction of a disulfide-based armed antibody is limited by an oxidative potential within endosomes and lysosomes. Proc Natl Acad Sci U S A. 102(50):17987-92, 2005.
Austin, C.D., De Maziere A.M., Pisacane P.I., van Dijk S.M., Eigenbrot C., Sliwkowski M.X., Klumperman .J, and Scheller R.H. Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin. 2004. Mol Biol. Cell 15:5268-82, 2004.
Peden, A.A., Oorschot, V., Hesser, B.A., Austin, C.D., Scheller, R.H., and Klumperman, J. Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins. J. Cell Biol. 164:1065-76, 2004.
Austin, C.D., Tiessen, J.R., Gopalan, A., Williams, J.M. Jr., Bangs, C.D., Cherry, A.M., Lehnert, B.A., and Rouse, R.V. Spindle cell lipoma of the foot and the application of CD34 immunohistochemistry to atypical lipomatous tumors in unusual locations. Appl Immunohistochem Molecul Morphol. 8:222-227, 2000.
Chen, Y-G., Siddhanta, A., Austin, C.D., Hammond, S.M., Sung, T.-C., Frohman, M.A., Morris, A.J., and Shields, D. Phospholipase D stimulates release of nascent secretory vesicles from the trans-Golgi network. J. Cell Biol. 138:495-504, 1997.
Austin, C.D. and Shields, D. The budding of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors. J. Cell Biol. 135:1471-1483, 1996.
Austin, C.D. and Shields, D. Prosomatostatin processing in permeabilized cells. Calcium is required for prohormone cleavage but not formation of nascent secretory vesicles. J. Biol. Chem. 271:1194-1199, 1996.
Austin, C.D. 1993. The connexins: a family of gap junction proteins. Einstein Quart. J. Biol. Med. 10:133-142.
Fox, J.E.B., Lipfert, L., Clark, E.A., Reynolds, C.C., Austin, C.D., and Brugge, J.S. On the role of the platelet membrane skeleton in mediating signal transduction. Association of GP Ilb-Illa, pp60c-src, pp62c-yes, and the p21ras GTPase-activating protein with the membrane skeleton. J. Biol. Chem. 268:25973-25984, 1993.
Fox, J.E.B., Austin, C.D., Reynolds, C.C., and Steffen, P.K. Evidence that agonist-induced activation of calpain causes the shedding of procoagulant-containing microvesicles from the membrane of aggregating platelets. J. Biol. Chem. 266:13289-13295, 1991.
Fox, J.E.B. , Austin, C.D., Boyles, J.K., and Steffen, P.K. Role of the membrane skeleton in preventing the shedding of procoagulant-rich microvesicles from the platelet plasma membrane. J. Cell Biol. 111:483-493, 1990.
Fox, J.E.B., Reynolds, C.C., and Austin, C.D. The role of calpain in stimulus-response coupling: evidence that calpain mediates agonist-induced expression of procoagulant activity in platelets. Blood 76:2510-2519, 1990.
Williams, W.F., Austin, C.D., Vasselli, B.G., Farnsworth, P.N., and Schleich, T. Phosphorus and proton magnetic resonance studies on the relationship between transparency and glucose metabolism in the rabbit lens. Exp. Eye Res. 47:97-112, 1988

Non-Peer Reviewed Publications
Lawrence, D.A., Marsters, S. A., Austin, C.D. TRAIL induces caspase-dependent cleavage of specific components of the clathrin-mediated endocytosis machinery. bioRxiv 2024.10.24.619217; doi: https://doi.org/10.1101/2024.10.24.619217
Kortmann, J., Huang, K., Tsai, MC., Barck, K., Jacobson, A., Austin, C.D., Dunlap, D., Chalouni, C., Jeet, S., Balestrini, A., Storm, E., Wilson, M.S., Deng, L., Dourado, M., Hackos, D., Riol-Blanco, L., Kaminker, J.S., Turley, S.J. Lung-innervating neurons expressing Tmc3 can induce broncho-constriction and dilation with direct consequences for the respiratory cycle. bioRxiv 2023.08.24.554567; doi: https://doi.org/10.1101/2023.08.24.554567
Austin, C.D. 1996. Prohormone processing and secretory vesicle formation in vitro: roles for calcium and phosphotyrosine metabolism. Ph.D. Thesis Dissertation, Sue Golding Graduate Division of Medical Sciences, Albert Einstein College of Medicine, Bronx, NY.