Education
PhD, Indian Institute of Science, Bengaluru, India, 2024
Lab information
Dr. Sivaprakasam Ramamoorthy
https://cbr-iisc.ac.in/sivaprakasam-ramamoorthy/
Publications
https://scholar.google.com/citations?user=OENYgH0AAAAJ&hl=en1) Agarwal A, and Muniyappa K. (2024) Mycobacterium smegmatis Holliday junction resolvases RuvC and RuvX play complementary roles in processing DNA replication/recombination intermediates. J Biol Chem. DOI: 10.10.1016/j.jbc.
2024.107732.
2) Bhattacharya S, Agarwal A, Muniyappa K. (2024) Deciphering the substrate specificity reveals that CRISPR-Cas12a is a bifunctional enzyme with both endo- and exonuclease activities. J Mol Biol. 436,168550.
3) Thakur, M., Agarwal, A., and Muniyappa, K. (2021). The intrinsic ATPase activity of Mycobacterium tuberculosis UvrC is crucial for its damage-specific DNA incision function. FEBS J. 288, 1179–1200.
4) Thakur, M., Mohan, D., Singh, A. K., Agarwal, A., Gopal, B., and Muniyappa, K. (2021) Novel insights into ATP-stimulated cleavage of Branched DNA and RNA Substrates through Structure-Guided Studies of the Holliday Junction Resolvase RuvX. J. Mol. Biol. 433, 167014.