Education
Ph.D. in Pharmacology, Department of Pharmacology, Complutense University, Madrid, Spain, 2005
Current Position
Miguel Servet Researcher, Instituto de Investigación Hospital Universitario La PAZ, Madrid, Spain
Publications (since 2005)
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Fernandez-Velasco, M., Ruiz-Hurtado, G., Rueda, A., Neco, P., Mercado-Morales, M., Delgado, C., Napolitano, C., Priori, S. G., Richard, S., Gomez, A. M. and Benitah, J. P. (2011). RyRCa2+ leak limits cardiac Ca2+ window current overcoming the tonic effect of calmodulinin mice. PLoS One 6(6): e20863.
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Smani, T., Calderon-Sanchez, E., Gomez-Hurtado, N., Fernandez-Velasco, M., Cachofeiro, V., Lahera, V., Ordonez, A. and Delgado, C. (2010). Mechanisms underlying the activation of L-type calcium channels by urocortin in rat ventricular myocytes. Cardiovasc Res 87(3): 459-466.
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Prieto, P., Cuenca, J., Traves, P. G., Fernandez-Velasco, M., Martin-Sanz, P. and Bosca, L. (2010). Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways. Cell Death Differ 17(7): 1179-1188.
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Prieto, P., Cuenca, J., Traves, P. G., Fernandez-Velasco, M., Martin-Sanz, P. and Bosca, L. (2010). Lipoxin A4 impairment of apoptotic signaling in macrophages: implication of the PI3K/Akt and the ERK/Nrf-2 defense pathways. Cell Death Differ 17(7): 1179-1188.
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Fernandez-Velasco, M., Rueda, A., Rizzi, N., Benitah, J. P., Colombi, B., Napolitano, C., Priori, S. G., Richard, S. and Gomez, A. M. (2009). Increased Ca2+ sensitivity of the ryanodine receptor mutant RyR2R4496C underlies catecholaminergic polymorphic ventricular tachycardia. Circ Res 104(2): 201-209, 212p following 209.
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Loyer, X., Gomez, A. M., Milliez, P., Fernandez-Velasco, M., Vangheluwe, P., Vinet, L., Charue, D., Vaudin, E., Zhang, W., Sainte-Marie, Y., Robidel, E., Marty, I., Mayer, B., Jaisser, F., Mercadier, J. J., Richard, S., Shah, A. M., Benitah, J. P., Samuel, J. L. and Heymes, C. (2008). Cardiomyocyte overexpression of neuronal nitric oxide synthase delays transition toward heart failure in response to pressure overload by preserving calcium cycling. Circulation 117(25): 3187-3198.
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Gellen, B., Fernandez-Velasco, M., Briec, F., Vinet, L., LeQuang, K., Rouet-Benzineb, P., Benitah, J. P., Pezet, M., Palais, G., Pellegrin, N., Zhang, A., Perrier, R., Escoubet, B., Marniquet, X., Richard, S., Jaisser, F., Gomez, A. M., Charpentier, F. and Mercadier, J. J. (2008). Conditional FKBP12.6 overexpression in mouse cardiac myocytes prevents triggered ventricular tachycardia through specific alterations in excitation-contraction coupling. Circulation 117(14): 1778-1786.
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Ruiz-Hurtado, G., Fernandez-Velasco, M., Mourelle, M. and Delgado, C. (2007). LA419, a novel nitric oxide donor, prevents pathological cardiac remodeling in pressure-overloaded rats via endothelial nitric oxide synthase pathway regulation. Hypertension 50(6): 1049-1056.
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Pereira, L., Metrich, M., Fernandez-Velasco, M., Lucas, A., Leroy, J., Perrier, R., Morel, E., Fischmeister, R., Richard, S., Benitah, J. P., Lezoualc'h, F. and Gomez, A. M. (2007). The cAMP binding protein Epac modulates Ca2+ sparks by a Ca2+/calmodulin kinase signalling pathway in rat cardiac myocytes. J Physiol 583(Pt 2): 685-694.
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Fernandez-Velasco, M., Ruiz-Hurtado, G., Hurtado, O., Moro, M. A. and Delgado, C. (2007). TNF-alpha downregulates transient outward potassium current in rat ventricular myocytes through iNOS overexpression and oxidant species generation. Am J Physiol Heart Circ Physiol 293(1): H238-245.
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Fernandez-Velasco, M., Gomez, A. M. and Richard, S. (2006). Unzipping RyR2 in adult cardiomyocytes: getting closer to mechanisms of inherited ventricular arrhythmias? Cardiovasc Res 70(3): 407-409.
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Fernandez-Velasco, M., Ruiz-Hurtado, G. and Delgado, C. (2006). I K1 and I f in ventricular myocytes isolated from control and hypertrophied rat hearts. Pflugers Arch 452(2): 146-154.
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Zicha, S., Fernandez-Velasco, M., Lonardo, G., L'Heureux, N. and Nattel, S. (2005). Sinus node dysfunction and hyperpolarization-activated (HCN) channel subunit remodeling in a canine heart failure model. Cardiovasc Res 66(3): 472-481.