Education

PhD, University of Iowa, 2014

Lab information

Tatiana Mishanina lab is interested in the underlying molecular mechanisms of gene expression in human mitochondria and bacteria. We use a combination of biochemical and structural biology approaches to study how RNA polymerase, the central enzyme in gene expression, contributes to gene regulation via transcriptional pausing; how it couples RNA synthesis to DNA replication, RNA processing and modification in mitochondria, and how we can control these processes to rationally manipulate gene expression for antimicrobials and treatments of disease.
http://mishaninalab.ucsd.edu/

Research focus

transcription, biochemistry, structural biology, RNA, bacterial transcription, mitochondrial transcription

Publications