Education

PhD, University of Kaiserslautern, 2016

Lab information

Timothy Stasevich and Brian Munsky Labs

Research focus

My research focuses on studying transcription dynamics at a single-copy gene and single-molecule resolution level. To this aim, I employ two main techniques: (1) FabLEM: Fab (fragmented antibodies)-based imaging of Live, Endogenous Modifications to identify posttranslational modifications such as phosphorylations, acetylations, methylations, e.g., Ser5ph of RNAP2. (2) smiFISH (single-molecule inexpensive fluorescence in situ hybridization) to light up endogenous genes transcriptionally active and inactive. Currently, I am studying the gene expression of pro- and counter-inflammatory genes upon stimulation with cytokines and glucocorticoids.

Publications