Wei Hsu Forsyth Institute/Harvard University Cambridge

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Hsiao-Man Yu Forsyth Institute Cambridge
1 protocol

Takamitsu Maruyama Forsyth Institute Cambridge
1 protocol

Wei Hsu

Faculty, Forsyth Institute/Harvard University Cambridge

Research focus

We are interested in the mechanisms that support embryonic morphogenesis, tissue homeostasis, disease pathogenesis, and organ repair and regeneration. Focusing initially on Wnt as one of the most prevalent signaling pathways in developmental biology, we are establishing how Wnt signaling and its crosstalk with other pathways control pluripotency and differentiation in stem cells and homeostasis in mature cells. More recently, we have also focused on epigenetic, post-translational, ciliogenesis, mitochondrial regulation, and nuclear lamina causally linked to human diseases. Our goal is to use this basic knowledge to develop innovative strategies for disease prevention and therapy.

1 Author merit
Reviewer merit
Editor merit

Education

Ph. D., Icahn School of Medicine at Mount Sinai, 1994

Lab information

Wei Hsu Lab: Morphogenetic Signaling Network in Development and Disease
https://connects.catalyst.harvard.edu/Profiles/display/Person/199173

Publications

https://www.ncbi.nlm.nih.gov/myncbi/wei.hsu.1/bibliography/public/

1 Protocol published

Skeletal Stem Cell Isolation from Cranial Suture Mesenchyme and Maintenance of Stemness in Culture

Authors: Takamitsu Maruyama, Hsiao-Man Ivy Yu and Wei Hsu, date: 03/05/2022, view: 582, Q&A: 0

Skeletal stem cells residing in the suture mesenchyme are responsible for calvarial development, homeostatic maintenance, and injury-induced repair. These naïve cells exhibit long-term self-renewal, clonal expansion, and multipotency. They

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