Darren R. Carpizo University of Rochester School Medicine and Dentistry

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Stewart Loh Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse
1 protocol

Xin Yu Rutgers Cancer Institute of New Jersey New Brunswick
1 protocol

Jeung- Ha Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse
1 protocol

Darren R. Carpizo

University of Rochester School of Medicine and Dentistry Rochester

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1 Protocol published

Urea Denaturation, Zinc Binding, and DNA Binding Assays of Mutant p53 DNA-binding Domains and Full-length Proteins

Authors: Jeung-Hoi Ha, Xin Yu, Darren R. Carpizo and Stewart N. Loh, date: 10/20/2021, view: 934, Q&A: 0

In the cell, the thermodynamic stability of a protein – and hence its biological activity – can change dramatically as a result of perturbations in its amino acid sequence and the concentration of stabilizing ligands. This interplay is

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