Role of macrophage signaling in chronic kidney diseases. Mitochondrial dysfunction in acute and chronic kidney diseases. Preeclampsia pathogenesis and treatment.
1. Zsengellér, Z.K., Wert, S.E., Hull, W.M., Hu, X., Yei, S., Trapnell, B.C. and Whitsett, J.A.: Persistence of replication deficient adenoviral mediated gene transfer in lungs of immune -deficient (nu/nu) mice. Hum. Gene Therapy 6: 457-467, 1995.
2. Zsengellér, Z.K., Boivin, G., Sawchuk, S.S., Trapnell, B.C., Whitsett, J.A. and Hirsch, R.: Anti-T cell receptor antibody prolongs transgene expression and reduces lung inflammation after adenovirus-mediated gene transfer. Hum. Gene Therapy 8: 935-941, 1997.
3. Zsengellér, Z.K., Wert, S.E., Bachurski C.J., Kervin K.L., Trapnell, B. C. and Whitsett, J.A.: Recombinant adenoviral vector disrupts surfactant homeostasis in mouse lung. Hum. Gene Therapy 8:1331-1344, 1997.
4. Huffman Reed, J.A., Rice, W.R., Zsengellér, Z.K., Wert, S.E., Drenoff G., and Whitsett, J.A.: GM-CSF expression enhances lung growth and causes alveolar Type II epithelial cell hyperplasia in transgenic mice. American Journal of Physiology: Lung Cellular and Molecular Physiology 273: L715-725, 1997.
5. Zingarelli B., Cuccocrea, S., Zsengellér, Z., Salzman, A.L., Szabo, Cs.: Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP- ribose) synthetase. Cardiovascular Research 36:205-215, 1997.
6. Zsengellér, Z.K.; Reed, J.A., Bachurski, C.J., LeVine, A.m., Forry-Schaudies, S., Hirsch, R. and Whitsett, J.A.: Adenovirus-mediated granulocyte-macrophage colony-stimulating factor improves lung pathology of pulmonary alveolar proteinosis in granulocyte-macrophage colony-stimulating factor-deficient mice. Hum. Gene Ther. 9:2101-2109,1998.
7. Zsengellér, Z.K., Halbert C., Miller, A. D., Wert, S.E., Whitsett, J. A., and Bachurski, C. J.: Keratinocyte growth factor stimulates transduction of the respiratory epithelium by retroviral vectors. Hum. Gene Ther. 10:341-353, 1999.
8. Zsengellér, Z.K., Otake, K., Hossain, S. A., Berclaz, P. Y. and Trapnell, B.C.: Internalization of adenovirus by alveolar macrophages initiates early proinflammatory signaling during acute respiratory tract infection. J. Virol 74: 9655-9667, 2000
9. Zsengellér, Z.K., Ross, G., Trapnell, B. C. Szabó, C. and Whitsett, J. A.: Adenovirus infection increases iNOS and peroxynitrite production in the lung. Am J Physiol Lung Cell Mol Physiol. Mar;280(3):L503-11. 2001
10. Shibata, Y., Zsengellér, Z.K., Otake, K., Palaniyar, N., and Trapnell, B.C.: Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema. Blood. 98(9):2845-52, 2001.
11. Berclaz PY, Zsengeller Z, Shibata Y, Otake K, Strasbaugh S, Whitsett JA, Trapnell BC. Endocytic internalization of adenovirus, nonspecific phagocytosis, and cytoskeletal organization are coordinately regulated in alveolar macrophages by GM-CSF and PU.1. J Immunol. 2002 Dec 1;169(11):6332-42.
12. Okinaga S, Slattery D, Humbles A, Zsengeller Z, Morteau O, Kinrade MB, Brodbeck RM, Krause JE, Choe HR, Gerard NP, Gerard C. C5L2, a nonsignaling C5A binding protein. Biochemistry. 2003 Aug 12;42(31):9406-15.
13. Du X, Matsumura T, Edelstein D, Rossetti L, Zsengeller Z, Szabo C, Brownlee M. Free in PMC Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest. 2003 Oct;112(7):1049-57.
14. Murakami K, Enkhbaatar P, Shimoda K, Cox RA, Burke AS, Hawkins HK, Traber LD, Schmalstieg FC, Salzman AL, Mabley JG, Komjati K, Pacher P, Zsengeller Z, Szabo C, Traber DL. Inhibition of poly (ADP-ribose) polymerase attenuates acute lung injury in an ovine model of sepsis. Shock. 2004 Feb;21(2):126-33.
15. Xiao CY, Chen M, Zsengeller Z, Szabo C. Poly(ADP-ribose) polymerase contributes to the development of myocardial infarction in diabetic rats and regulates the nuclear translocation of apoptosis-inducing factor. J Pharmacol Exp Ther. 2004 Aug;310(2):498-504.
16. Szabo G, Soos P, Bahrle S, Zsengeller Z, Flechtenmacher C, Hagl S, Szabo C.Role of poly(ADP-ribose) polymerase activation in the pathogenesis of cardiopulmonary dysfunction in a canine model of cardiopulmonary bypass. Eur J Cardiothorac Surg. 2004 May;25(5):825-32.
17. Szabo G, Soos P, Mandera S, Heger U, Flechtenmacher C, Bahrle S, Seres L, Cziraki A, Gries A, Zsengeller Z, Vahl CF, Hagl S, Szabo C. INO-1001 a novel poly(ADP-ribose) polymerase (PARP) inhibitor improves cardiac and pulmonary function after crystalloid cardioplegia and extracorporal circulation. Shock. 2004 May;21(5):426-32.
18. Obrosova IG, Minchenko AG, Frank RN, Seigel GM, Zsengeller Z, Pacher P, Stevens MJ, Szabo C. Poly(ADP-ribose) polymerase inhibitors counteract diabetes- and hypoxia-induced retinal vascular endothelial growth factor overexpression. Int J Mol Med. 2004 Jul;14(1):55-64.
19. Chen M, Zsengeller Z, Xiao CY, Szabo C. Mitochondrial-to-nuclear translocation of apoptosis-inducing factor in cardiac myocytes during oxidant stress: potential role of poly(ADP-ribose) polymerase-1.Cardiovasc Res. 2004 Sep 1;63(4):682-8
20. Szabo C, Pacher P, Zsengeller Z, Vaslin A, Komjati K, Benko R, Chen M, Mabley JG, Kollai M. Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation. Mol Med. 2004 Jan-Jun;10(1-6):28-35.
21. Xiao CY, Chen M, Zsengeller Z, Li H, Kiss L, Kollai M, Szabo C. Poly(ADP-Ribose) polymerase promotes cardiac remodeling, contractile failure, and translocation of apoptosis-inducing factor in a murine experimental model of aortic banding and heart failure. J Pharmacol Exp Ther. 2005 Mar;312(3):891-8.
22. Szabo G, Seres L, Soos P, Flechtenmacher C, Zsengeller Z, Sack FU, Szabo C, Hagl S. Poly-ADP-ribose polymerase inhibition reduces mesenteric injury after cardiopulmonary bypass. Thorac Cardiovasc Surg. 2004 Dec;52(6):338-43.
23. Szabo G, Soos P, Mandera S, Heger U, Flechtenmacher C, Seres L, Zsengeller Z, Sack FU, Szabo C, Hagl S. Mesenteric injury after cardiopulmonary bypass: role of poly(adenosine 5'-diphosphate-ribose) polymerase. Crit Care Med. 2004 Dec;32(12):2392-7.
24. Obrosova IG, Mabley JG, Zsengeller Z, Charniauskaya T, Abatan OI, Groves JT, Szabo C. Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst. FASEB J. 2005 Mar;19(3):401-3.
25. Obrosova IG, Pacher P, Szabo C, Zsengeller Z, Hirooka H, Stevens MJ, Yorek MA. Aldose reductase inhibition counteracts oxidative-nitrosative stress and poly(ADP-ribose) polymerase activation in tissue sites for diabetes complications.Diabetes. 2005 Jan;54(1):234-42.
26. Szabo G, Soos P, Heger U, Flechtenmacher C, Bahrle S, Zsengeller Z, Szabo C, Hagl S. Poly(ADP-ribose) polymerase inhibition attenuates biventricular reperfusion injury after orthotopic heart transplantation. Eur J Cardiothorac Surg. 2005 Feb;27(2):226-34.
27. Besson VC, Zsengeller Z, Plotkine M, Szabo C, Marchand-Verrecchia C. Beneficial effects of PJ34 and INO-1001, two novel water-soluble poly(ADP-ribose) polymerase inhibitors, on the consequences of traumatic brain injury in rat. Brain Res. 2005 Apr 18;1041(2):149-56.
28. Mabley JG, Horvath EM, Murthy KG, Zsengeller Z, Vaslin A, Benko R, Kollai M, Szabo C. Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation. J Pharmacol Exp Ther. 2005 Nov;315(2):812-20.
29. Kendirci M, Zsengeller Z, Bivalacqua TJ, Gur S, Usta MF, Chen M, Szabo C, Hellstrom WJ. Poly(Adenosine diphosphate-ribose) polymerase inhibition preserves erectile function in rats after cavernous nerve injury. J Urol. 2005 Nov;174(5):2054-9.
30. Soriano FG, Nogueira AC, Caldini EG, Lins MH, Teixeira AC, Cappi SB, Lotufo PA, Bernik MM, Zsengeller Z, Chen M, Szabo C. Potential role of poly(adenosine 5'-diphosphate-ribose) polymerase activation in the pathogenesis of myocardial contractile dysfunction associated with human septic shock. Crit Care Med. 2006 Apr;34(4):1073-9.
31. Ramlawi B, Feng J, Mieno S, Szabo C, Zsengeller Z, Clements R, Sodha N, Boodhwani M, Bianchi C, Sellke FW. Indices of apoptosis activation after blood cardioplegia and cardiopulmonary bypass. Circulation. 2006 Jul 4;114(1 Suppl):I257-63.
32. Toth-Zsamboki E, Horvath E, Vargova K, Pankotai E, Murthy K, Zsengeller Z, Barany T, Pek T, Fekete K, Kiss RG, Preda I, Lacza Z, Gero D, Szabo C. Activation of poly(ADP-ribose) polymerase by myocardial ischemia and coronary reperfusion in human circulating leukocytes. Mol Med. 2006 Sep-Oct;12(9-10):221-8.
33. Mukhopadhyay P, Bátkai S, Rajesh M, Czifra N, Harvey-White J, Haskó G, Zsengeller Z, Gerard NP, Liaudet L, Kunos G, Pacher P. Pharmacological inhibition of CB1 cannabinoid receptor protects against doxorubicin-induced cardiotoxicity. J Am Coll Cardiol. 2007 Aug 7;50(6):528-36. Epub 2007 Jul 23.
34. Dib M, Zsengeller Z, Mitsialis A, Lu B, Craig S, Gerard C, Gerard NP A paradoxical protective role for the proinflammatory peptide substance P receptor (NK1R) in acute hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L687-97.
35. Silasi M, Rana S, Powe C, Cohen B, Lim KH, Zsengellér ZK, Karumanchi SA, Stillman IE. Placental expression of angiogenic factors in Trisomy 13.Am J Obstet Gynecol. 2011 Jun;204(6):546.e1-4.
36. Horvath EM, Zsengellér ZK, Szabo C. Quantification of PARP activity in human tissues: ex vivo assays in blood cells and immunohistochemistry in human biopsies. Methods Mol Biol. 2011;780:267-75.
37. Tran M, Tam D, Bardia A, Bhasin M, Rowe GC, Kher A, Zsengeller ZK, Akhavan-Sharif MR, Khankin EV, Saintgeniez M, David S, Burstein D, Karumanchi SA, Stillman IE, Arany Z, Parikh SM.PGC-1α promotes recovery after acute kidney injury during systemic inflammation in mice. J Clin Invest. 2011 Oct;121(10):4003-14.
38. Mukhopadhyay P, Horváth B, Zsengellér Z, Zielonka J, Tanchian G, Holovac E, Kechrid M, Patel V, Stillman IE, Parikh SM, Joseph J, Kalyanaraman B, Pacher P. Mitochondrial-targeted antioxidants represent a promising approach for prevention of cisplatin-induced nephropathy. Free Radic Biol Med. 2012 Jan 15;52(2):497-506.
39. Bixel K, Silasi M, Zelop CM, Lim KH, Zsengeller Z, Stillman IE, Rana S. Placental origins of angiogenic dysfunction in mirror syndrome. Hypertens Pregnancy. 2012;31(2):211-7.
40. Rajakumar A, Cerdeira AS, Rana S, Zsengeller Z, Edmunds L, Jeyabalan A, Hubel CA, Stillman IE, Parikh SM, Karumanchi SA. Transcriptionally active syncytial aggregates in the maternal circulation may contribute to circulating soluble fms-like tyrosine kinase 1 in preeclampsia. Hypertension. 2012 Feb;59(2):256-64.
41. Zsengellér ZK, Ellezian L, Brown D, Horváth B, Mukhopadhyay P, Kalyanaraman B, Parikh SM, Karumanchi SA, Stillman IE, Pacher P. Cisplatin nephrotoxicity involves mitochondrial injury with impaired tubular mitochondrial enzyme activity. J Histochem Cytochem. 2012 Jul;60(7):521-9.
42. Mukhopadhyay P, Horváth B, Zsengellėr Z, Bátkai S, Cao Z, Kechrid M, Holovac E, Erdėlyi K, Tanchian G, Liaudet L, Stillman IE, Joseph J, Kalyanaraman B, Pacher P. Mitochondrial reactive oxygen species generation triggers inflammatory response and tissue injury associated with hepatic ischemia-reperfusion: therapeutic potential of mitochondrially targeted antioxidants. Free Radic Biol Med. 2012 Sep 1;53(5):1123-38.
43. Reimold FR, Braun N, Zsengellér ZK, Stillman IE, Karumanchi SA, Toka HR, Latus J, Fritz P, Biegger D, Segerer S, Alscher MD, Bhasin MK, Alper SL. Transcriptional patterns in peritoneal tissue of encapsulating peritoneal sclerosis, a complication of chronic peritoneal dialysis. PLoS One. 2013;8(2):e56389.
44. Rowe GC, Patten IS, Zsengeller ZK, El-Khoury R, Okutsu M, Bampoh S, Koulisis N, Farrell C, Hirshman MF, Yan Z, Goodyear LJ, Rustin P, Arany Z. Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle. Cell Rep. 2013 May 30;3(5):1449-56.
45. Holwerda KM, Burke SD, Faas MM, Zsengeller Z, Stillman IE, Kang PM, van Goor H, McCurley A, Jaffe IZ, Karumanchi SA, Lely AT. Hydrogen sulfide attenuates sFlt1-induced hypertension and renal damage by upregulating vascular endothelial growth factor. J Am Soc Nephrol. 2014 Apr;25(4):717-25.
46. Zsengellér ZK, Aljinovic N, Teot LA, Korson M, Rodig N, Sloan JL, Venditti CP, Berry GT, Rosen S. Methylmalonic acidemia: A megamitochondrial disorder affecting the kidney. Pediatr Nephrol. 2014 Nov;29(11):2139-46.
47. Baltajian K, Hecht JL, Wenger JB, Salahuddin S, Verlohren S, Perschel FH, Zsengeller ZK, Thadhani R, Karumanchi SA, Rana S. Placental lesions of vascular insufficiency are associated with anti-angiogenic state in women with preeclampsia. Hypertens Pregnancy. 2014 Nov;33(4):427-39.
48. Erpenbeck L, Demers M, Zsengellér ZK, Gallant M, Cifuni SM, Stillman IE, Karumanchi SA, Wagner DD. ADAMTS13 Endopeptidase Protects against Vascular Endothelial Growth Factor Inhibitor-Induced Thrombotic Microangiopathy. J Am Soc Nephrol. 2015 Jun 2. pii: ASN.2014121165.
49. Reimold FR, Balasubramanian S, Doroquez DB, Shmukler BE, Zsengeller ZK, Saslowsky D, Thiagarajah JR, Stillman IE, Lencer WI, Wu BL, Villalpando-Carrion S, Alper SL. Congenital chloride-losing diarrhea in a Mexican child with the novel homozygous SLC26A3 mutation G393W. Front Physiol. 2015 Jun 23;6:179
50. Wang A, Zsengellér ZK, Hecht JL, Buccafusca R, Burke SD, Rajakumar A, Weingart E, Yu PB, Salahuddin S, Karumanchi SA. Excess placental secreted frizzled-related protein 1 in maternal smokers impairs fetal growth. J Clin Invest. 2015 Nov 2;125(11):4021-5.
51. Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM.PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature. 2016 Mar 24;531(7595):528-32. PMID: 26982719
52. Hecht JL, Zsengeller ZK, Spiel M, Karumanchi SA, Rosen S Revisiting decidual vasculopathy. Placenta. 2016 Jun;42:37-43. PMID: 27238712
53. Burke SD, Zsengellér ZK, Khankin EV, Lo AS, Rajakumar A, DuPont JJ, McCurley A, Moss ME, Zhang D, Clark CD, Wang A, Seely EW, Kang PM, Stillman IE, Jaffe IZ, Karumanchi SA. Soluble fms-like tyrosine kinase 1 promotes angiotensin II sensitivity in preeclampsia. J Clin Invest. 2016 Jul 1;126(7):2561-74.PMID: 27270170
54. Zsengellér ZK, Rosen S. The Use of Cytochrome C Oxidase Enzyme Activity and Immunohistochemistry in Defining Mitochondrial Injury in Kidney Disease. J Histochem Cytochem. 2016 Sep;64(9):546-55 PMID: 27578326
55. Zsengellér ZK, Rajakumar A, Hunter JT, Salahuddin S, Rana S, Stillman IE, Ananth Karumanchi S. Trophoblast mitochondrial function is impaired in preeclampsia and correlates negatively with the expression of soluble fms-like tyrosine kinase 1. Pregnancy Hypertens. 2016 Oct;6(4):313-319.
56. DuBrock HM, Rodriguez-Lopez JM, LeVarge BL, Curry MP, VanderLaan PA, Zsengeller ZK, Pernicone E, Preston IR, Yu PB, Nikolic I, Xu D, Thadhani RI, Channick RN, Ananth Karumanchi S. Macrophage migration inhibitory factor as a novel biomarker of portopulmonary hypertension. Pulm Circ. 2016 Dec;6(4):498-507. PMID: 28090291
57. Erpenbeck L, Chowdhury CS, Zsengellér ZK, Gallant M, Burke SD, Cifuni S, Hahn S, Wagner DD, Karumanchi SA. PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model. Biol Reprod. 2016 Dec;95(6):132. doi: 10.1095/biolreprod.116.140293. Epub 2016 Nov 9. PMID: 28007693
58. Horvath EM, Zsengellér ZK, Szabo C. Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies. Methods Mol Biol. 2017;1608:19-26. PMID: 28695500
59. Vichot AA, Zsengellér ZK, Shmukler BE, Adams ND, Dahl NK, Alper SL. Loss of kAE1 expression in collecting ducts of end-stage kidneys from a family with SLC4A1 G609R-associated distal renal tubular acidosis. Clin Kidney J. 2017 Feb;10(1):135-140 PMID: 28638614
60. Spiel M, Salahuddin S, Pernicone E, Zsengeller Z, Wang A, Modest AM, Karumanchi SA, Hecht JL. Placental soluble fms-like tyrosine kinase expression in small for gestational age infants and risk for adverse outcomes. Placenta. 2017 Apr;52:10-16. PMID: 28454690
61. Paauw ND, Joles JA, Spradley FT, Bakrania B, Zsengeller ZK, Franx A, Verhaar MC, Granger JP, Lely AT.Exposure to placental ischemia impairs postpartum maternal renal and cardiac function in rats. Am J Physiol Regul Integr Comp Physiol. 2017 May 1;312(5):R664-R670. PMID: 28202440
62. Nezu M, Souma T, Yu L, Sekine H, Takahashi N, Wei AZ, Ito S, Fukamizu A, Zsengeller ZK, Nakamura T, Hozawa A, Karumanchi SA, Suzuki N, Yamamoto M. Nrf2 inactivation enhances placental angiogenesis in a preeclampsia mouse model and improves maternal and fetal outcomes. Sci Signal. 2017 May 16;10(479). PMID: 28512147
63. Hecht JL, Ordi J, Carrilho C, Ismail MR, Zsengeller ZK, Karumanchi SA, Rosen S. The pathology of eclampsia: An autopsy series. Hypertens Pregnancy. 2017 Jul 5:1-10. PMID: 28678644
64. Shainker SA, Dannheim K, Gerson KD, Neo D, Zsengeller ZK, Pernicone E, Karumanchi SA, Hacker MR, Hecht JL. Down-regulation of soluble fms-like tyrosine kinase 1 expression in invasive placentation. Arch Gynecol Obstet. 2017 Aug;296(2):257-262. PMID: 28631072
65. Horvath EM, Zsengellér ZK, Szabo C. Quantification of PARP Activity in Human Tissues: Ex Vivo Assays in Blood Cells and Immunohistochemistry in Human Biopsies.Methods Mol Biol. 2017;1608:19-26. PMID: 28695500
66. Drury ER, Zsengeller ZK, Stillman IE, Khankin EV, Pavlakis M, Parikh SM. Renal PGC1α May Be Associated with Recovery after Delayed Graft Function. Nephron. 2017 Dec 21. doi: 10.1159/000485663 PMID: 29268263
67. Varga ZV, Erdelyi K, Paloczi J, Cinar R, Zsengeller ZK, Jourdan T, Matyas C, Nemeth BT, Guillot A, Xiang X, Mehal A, Haskó G, Stillman IE, Rosen S, Gao B, Kunos G, Pacher P. Disruption of Renal Arginine Metabolism Promotes Kidney Injury in Hepatorenal Syndrome in Mice. Hepatology. 2018 Oct;68(4):1519-1533. PMID: 29631342
68. Sircar M, Rosales IA, Selig MK, Xu D, Zsengeller ZK, Stillman IE, Libermann TA, Karumanchi SA, Thadhani RI. Complement 7 Is Up-Regulated in Human Early Diabetic Kidney Disease. Am J Pathol. 2018 Oct;188(10):2147-2154. PMID: 30253844
69. Covarrubias AE, Lecarpentier E, Lo A, Salahuddin S, Gray KJ, Karumanchi SA, Zsengellér ZK.AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis. Am J Pathol. 2019 Jan;189(1):104-114. PMID: 30315766
70. Turanov AA, Lo A, Hassler MR, Makris A, Ashar-Patel A, Alterman JF, Coles AH, Haraszti RA, Roux L, Godinho BMDC, Echeverria D, Pears S, Iliopoulos J, Shanmugalingam R, Ogle R, Zsengeller ZK, Hennessy A, Karumanchi SA, Moore MJ, Khvorova A. RNAi modulation of placental sFLT1 for the treatment of preeclampsia. Nat Biotechnol. 2018 Nov 19. doi: 10.1038/nbt.4297. [Epub ahead of print] PMID: 30451990
71. Lynch MR, Tran MT, Ralto KM, Zsengeller ZK, Raman V, Bhasin SS, Sun N, Chen X, Brown D, Rovira II, Taguchi K, Brooks CR, Stillman IE, Bhasin MK, Finkel T, Parikh SM. TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance. JCI Insight. 2019 Mar 14;5. PMID: 30870143
72. Yonekura Collier AR, Zsengeller Z, Pernicone E, Salahuddin S, Khankin EV, Karumanchi SA. Placental sFLT1 is associated with complement activation and syncytiotrophoblast damage in preeclampsia. Hypertens Pregnancy. 2019 Jul
73. Zsengellér ZK, Lo A, Tavasoli M, Pernicone E, Karumanchi SA, Rosen S Soluble fms-Like Tyrosine Kinase 1 Localization in Renal Biopsies of CKD.cKidney Int Rep. 2019 Aug 14;4(12):1735-1741. PMID: 31844810
74. Zsengellér ZK, Gerard NP. The oxidation state of cysteine thiols on the ectodomain of TLR2 and TLR4 influences intracellular signaling. Immunobiology. 2019 Dec 5:151895. PMID: 31843260