Zheng Hou
  • Associate professor, Department of Pharmacology, Fourth Military Medical University, Xi'an, 2014-
Research fields
  • -
Personal information


PhD, Fourth Military Medical University, Xi'an, China, 2009


• Wang, M., Fang, C., Ma, B., Luo, X. and Hou, Z. (2020). Regulation of cytokinesis: FtsZ and its accessory proteins. Curr Genet 66(1): 43-49.
• Ma, B., Fang, C., Lu, L., Wang, M., Xue, X., Zhou, Y., Li, M., Hu, Y., Luo, X. and Hou, Z. (2019). The antimicrobial peptide thanatin disrupts the bacterial outer membrane and inactivates the NDM-1 metallo-beta-lactamase. Nat Commun 10(1): 3517
• Zhou, Y., Niu, C., Ma, B., Xue, X., Li, Z., Chen, Z., Li, F., Zhou, S., Luo, X. and Hou, Z. (2018). Inhibiting PSMalpha-induced neutrophil necroptosis protects mice with MRSA pneumonia by blocking the agr system. Cell Death Dis 9(3): 362.
• Li, Z., Zheng, Q., Xue, X., Shi, X., Zhou, Y., Da, F., Qu, D., Hou, Z. and Luo, X. (2016). Pyroptosis of Salmonella Typhimurium-infected macrophages was suppressed and elimination of intracellular bacteria from macrophages was promoted by blocking QseC. Sci Rep 6: 37447.
• Ma, B., Niu, C., Zhou, Y., Xue, X., Meng, J., Luo, X. and Hou, Z. (2016). The Disulfide Bond of the Peptide Thanatin Is Dispensible for Its Antimicrobial Activity In Vivo and In Vitro. Antimicrob Agents Chemother 60(7): 4283-4289.
• Zhou, Y., Zhao, R., Ma, B., Gao, H., Xue, X., Qu, D., Li, M., Meng, J., Luo, X. and Hou, Z. (2016). Oligomerization of RNAIII-Inhibiting Peptide Inhibits Adherence and Biofilm Formation of Methicillin-Resistant Staphylococcus aureus In Vitro and In Vivo. Microb Drug Resist 22(3): 193-201.
• Hou, Z., Zhou, Y., Li, J., Zhang, X., Shi, X., Xue, X., Li, Z., Ma, B., Wang, Y., Li, M. and Luo, X. (2015). Selective in vivo and in vitro activities of 3,3'-4-nitrobenzylidene-bis-4-hydroxycoumarin against methicillin-resistant Staphylococcus aureus by inhibition of DNA polymerase III. Sci Rep 5: 13637.
• Yin, S., Rao, G., Wang, J., Luo, L., He, G., Wang, C., Ma, C., Luo, X., Hou, Z. and Xu, G. (2015). Roemerine Improves the Survival Rate of Septicemic BALB/c Mice by Increasing the Cell Membrane Permeability of Staphylococcus aureus. PLoS One 10(11): e0143863.
• Ma, B., Zhou, Y., Li, M., Yu, Q., Xue, X., Li, Z., Da, F., Hou, Z. and Luo, X. (2015). RIP-V improves murine survival in a sepsis model by down-regulating RNAIII expression and alpha-hemolysin release of methicillin-resistant Staphylococcus aureus. Pharmazie 70(2): 81-87.
• Li, M., Li, J., Zhou, Y., Xue, X.-Y., Shi, X., Tu, Z.-y., Hou, Z. and Luo, X.-X. (2013). Synthesis, photoluminescent behaviors, and antibacterial activities of 3-acetylcoumarins. Res Chem Intermed 41(5):3289-3296.
• Li, J., Hou, Z., Chen, G. H., Li, F., Zhou, Y., Xue, X. Y., Li, Z. P., Jia, M., Zhang, Z. D., Li, M. K. and Luo, X. X. (2014). Synthesis, antibacterial activities, and theoretical studies of dicoumarols. Org Biomol Chem 12(29): 5528-5535.
• Lu, L., Hou, Z., Li, L., Yang, Y., Wang, X., Zhang, B., Ren, M., Zhao, D., Miao, Z., Yu, L. and Yao, Y. (2014). Methylation pattern of H19 exon 1 is closely related to preeclampsia and trophoblast abnormalities. Int J Mol Med 34(3): 765-771.
• Li, J., Hou, Z., Li, F., Zhang, Z., Zhou, Y., Luo, X.-X. and Li, M. (2014). Synthesis, photoluminescent, antibacterial activities and theoretical studies of 4-hydroxycoumarin derivatives. J Mol Stuct 1075: 509-514.
• Hou, Z., Da, F., Liu, B., Xue, X.-Y., Xu, X., Zhou, Y., Li, M., Li, Z., Ma, X., Meng, J., Jia, M., Wang, Y. and Luo, X.-X. (2013). R-thanatin inhibits the growth and biofilm formation of methicillin-resistant Staphylococcus epidermidis in vivo and in vitro. Antimicrob Agents Chemothe 57.
• Zhou, Y., Hou, Z., Fang, C., Xue, X., Da, F., Wang, Y., Bai, H. and Luo, X. (2013). Comparison of microplate and macrodilution methods in time-kill study of new antimicrobial drugs. Folia Microbiol (Praha) 58(1): 9-16.
• Li, M. K., Li, J., Liu, B. H., Zhou, Y., Li, X., Xue, X. Y., Hou, Z. and Luo, X. X. (2013). Synthesis, crystal structures, and anti-drug-resistant Staphylococcus aureus activities of novel 4-hydroxycoumarin derivatives. Eur J Pharmacol 721(1-3): 151-157.
• Hou, Z., Lu, J., Fang, C., Zhou, Y., Bai, H., Zhang, X., Xue, X., Chen, Y. and Luo, X. (2011). Underlying mechanism of in vivo and in vitro activity of C-terminal-amidated thanatin against clinical isolates of extended-spectrum beta-lactamase-producing Escherichia coli. J Infect Dis 203(2): 273-282.
• Hou, Z., Zhou, Y., Wang, H., Bai, H., Meng, J., Xue, X.-Y. and Luo, X.-X. (2011). Co-blockade of mecR1/blaR1 signal pathway to restore antibiotic susceptibility in clinical isolates of methicillin-resistant Staphylococcus aureus. Archives of medical science : AMS 7: 414-422.
• Hou, Z., Meng, J. Niu, C., Wang, H., Liu, J., Hu, B., Jia, M. and Luo, X. (2007). Restoration of antibiotic susceptibility in methicillin-resistant Staphylococcus aureus by targeting mecR1 with a phosphorothioate deoxyribozyme. Clin Exp Pharmacol Physiol 34: 1160-1164.
• Hou, Z., Meng, J. Zhao, J., Hu, B., Liu, J., Yan, X., Jia, M., and Luo, X. (2007).. Inhibition of β-lactamase-mediated oxacillin resistance in Staphylococcus aureus by a deoxyribozyme. Acta Pharmacol Sin 2007; 28: 1775-1782.
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