Francisco Navarro
  • Professor and Chair in Genetic, Experimental Biology, University of Jaen
Research fields
  • Molecular biology
Personal information


Ph.D in Biology, University of Seville, Spain, 1996


Since 2005
• Begley, Victoria; Corzo, Daniel; Jordán-Pla, Antonio,; Cuevas-Bermúdez, Abel; de Miguel, Maria; Pérez-Aguado, David; Machuca-Ostos, Mercedes; Navarro, Francisco; Chávez, María; Pérez-Ortín, José; Chavez, Sebastian (2019). The mRNA degradation factor Xrn1 regulates transcription elongation in parallel to Ccr4. Nucleic Acids Research. doi:10.1093/nar/gkz660.

• Cuevas-Bermúdez A, Garrido-Godino AI and Navarro F (2019). A novel yeast chromatin-enriched fractions purification approach, yChEFs, for the chromatin-associated protein analysis used for chromatin-associated and RNA-dependent chromatin-associated proteome studies from Saccharomyces cerevisiae. Gene Reports 16.

• Verónica Martínez-Fernández and Francisco Navarro (2018). Rpb5, a subunit shared by the eukaryotic RNA polymerases cooperates with the prefoldin-like Bud27/URI. AIMS Genetics, 5(1): 63-74. doi: 10.3934/genet.2018.1.63.

• Verónica Martínez-Fernández, Ana Isabel Garrido-Godino1, María Carmen Mirón-García, Victoria Begley, Antonio Fernández-Pévida, Jesús de la Cruz, Sebastián Chávez, and Francisco Navarro (2018). Rpb5 modulates the RNA polymerase II transition from initiation to elongation by influencing Spt5 association and backtracking. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1861(1):1-13. doi: 10.1016/j.bbagrm.2017.11.002.

• Garrido-Godino AI, Garcia-Lopez MC, Garcia-Martinez J, Pelechano V, Medina DA, Perez-Ortin JE, Navarro F (2016). Rpb1 foot mutations demonstrate a major role of Rpb4 in mRNA stability during stress situations in yeast. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms 1859: 731-743. doi: 10.1016/j.bbagrm.2016.03.008).
• Francisco Hernandez-Torres, Diego Franco, Amelia E. Aranega, and Francisco Navarro (2015). Expression patterns and immunohistochemical localization of PITX2B in the developing mouse heart. Int. J. Dev. Biol., Int. J. Dev. Biol. 59: 247 - 254 doi: 10.1387/ijdb.140224fh
• Mirón-García MC, Garrido-Godino AI, Martínez-Fernández V, Fernández-Pevida A, Cuevas-Bermúdez a, Chávez S, de la Cruz J and Navarro F (2014). The yeast URI-ortologue Bud27 associates with the RSC nucleosome remodeller and modulates transcription. NAR 42(15): 9666-9676.

• Paula Allepuz-Fuster, Verónica Martínez-Fernández, Ana I. Garrido-Godino, Sergio Alonso-Aguado, Steven D. Hanes, Francisco Navarro and Olga Calvo (2014). Rpb4/7 facilitates RNA polymerase II CTD dephosphorylation. NAR 42(22):13674-88.

• M. C. García-López, I. Vidoy, J. Jiménez-Ruiz, A. Muñoz-Mérida, A. Fernández-Ocaña, R. de la Rosa, J. B. Barroso, F. Navarro, O. Trelles, C. R. Beuzón, A. Barceló, V. Valpuesta, F. Luque (2014). Genetic changes involved in the juvenile-to-adult transition in the shoot apex of Olea europaea L. occurs years before the first flowering. Tree Genetics and Genomes, Volume 10, Issue 3, Page 585-603.

• Garrido-Godino AI, Garcia-Lopez MC, Navarro F. (2013). Correct assembly of the RNA polymerase II depends on the foot domain and is required for multiple steps of transcription in Saccharomyces cerevisiae. Mol Cell Biol. 33:3611-3626.

• Mirón-García MC, Garrido-Godino AI, García-Molinero V, Hernández-Torres F, Rodrıíguez-Navarro S, and Navarro F (2013). The Prefoldin Bud27 Mediates the Assembly of the Eukaryotic RNA Polymerases in an Rpb5-Dependent Manner. PLoS Genet 9 (2):e1003297.doi:10.1371/journal.pgen.1003297

• García-López MC, Pelechano V, Mirón-García MC, Garrido-Godino AI, García A, Calvo O, Werner M, Pérez-Ortín JE and Navarro F (2011). The conserved foot domain of RNA Pol II associates with proteins involved in transcriptional initiation and/or early elongation. Genetics, 84(4), 1235-48.

• García-López MC and Navarro F. (2011) RNA polymerase II conserved protein domains as platforms for protein-protein interactions. Transcription, 2:4, 193-197

• Lozano-Velasco E, Chinchilla A, Martínez-Fernández S, Hernández-Torres F, Navarro F, Lyons GE, Franco D, Aránega AE. (2011) Pitx2c modulates cardiac-specific transcription factors networks in differentiating cardiomyocytes from murine embryonic stem cells. Cells Tissues Organs 194(5):349-62.

• Fernández-Ocaña, A., García-López, MC., Jiménez-Ruiz, J., Saniger, L., Macías, D., Navarro, F., Oya, R., de la Rosa, R., Corpas, FJ., Barroso, JB., Luque, F. (2010) Identification of a gene involved in the juvenile-to-adult transition (JAT) in cultivated olive trees. Tree Genetics and Genomics 6, 891-903.

• García-López MC, Mirón-García MC, Garrido-Godino AI, Mingorance C and Navarro F. (2010) Overexpression of Sng1 causes 6-azauracil resistance in Saccharomyces cerevisiae. Current Genetics, 56 (3): 251-263

• Hernández-Torres F, Pedrajas Cabrera José Rafael, Aránega Amelia Eva And Navarro F (2008) Expression in bacteria of small and specific protein domains of two transcription factor isoforms, purification and monospecific polyclonal antibodies generation, by a two-step affinity chromatography procedure. Protein Expression and Purification, 60 , 151-156.

• Hernández-Torres F, Martínez-Fernandez S, Zuluaga S, Nebreda A, Porras A, Aránega AE, and Francisco Navarro (2008) A role for p38 mitogen-activated protein kinase in embryonic cardiac differentiation. Febs Letters 582, 1025-2031


• Cécile ZAROS, Jean-François BRIAND, Yves BOULARD, Sylvie LABARRE-MARIOTTE, M. Carmen GARCIA-LOPEZ, Pierre THURIAUX & Francisco NAVARRO (2007). Functional organisation of the Rpb5 subunit shared by the three yeast RNA polymerases. Nucleic Acid Research 35, 634-647

• Sergio Martínez-Fernandez, Francisco Hernández-Torres, Diego Franco, Gary E. Lyons, Francisco Navarro and Amelia E. Aránega (2006). Pitx2c overexpression promotes cell proliferation and arrests differentiation in myoblasts. Developmental Dynamics 235, 2930-9

• Julie SOUTOURINA, Véronique BORDAS-LE FLOCH, Gabrielle GENDREL, Amando FLORES, Cécile DUCROT, Hélène DUMAY-ODELOT, Pascal SOULARUE, Francisco NAVARRO, Bradley R. CAIRNS, Olivier LEFEBVRE and Michel WERNER (2006). Rsc4 connects the chromatin remodeler RSC to RNA polymerases.. Mol Cell Biol 26, pp.4920-4933

• Jorge N. Domínguez, Francisco Navarro, Diego Franco, Robert P. Thompson, Amelia E. Aránega (2005). Temporal and spatial expression pattern of a1 sodium channel subunit during heart development. Cardiovascular Research 65, pp. 842-850.
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.