Education
PhD, University of Florida, 2018
Lab information
Disinfectant policy and validation, regulatory policy on sterilization processes, contamination control strategies, aseptic process simulation
Research focus
Bacteriology, Biometals, Stress Tolerance, Pathogenesis, Physiology, Virulence, Pathophysiology
Publications
Colomer-Winter C, Flores-Mireles AL, Kundra S, Hultgren SJ, Lemos JA. "(p)ppGpp and CodY promote Enterococcus faecalis virulence in a murine model of catheter-associated urinary tract infection." mSphere 2019 4(4).pii:e00392-19.
Colomer-Winter C, Lemos JA, Flores-Mireles AL. “Biofilm assays on fibrinogen-coated silicone catheters and 96-well polystyrene plates.” Bio Protoc. 2019 Mar;9(6):e3196.
Colomer-Winter C, Gaca AO, Chuang-Smith ON, Lemos JA, Frank KL. “Cellular levels of (p)ppGpp differentially affect the pathogenesis of infective endocarditis in Enterococcus faecalis.” Microbiology 2018 Oct;164(10):1254-1265.
Colomer-Winter C, Flores-Mireles AL, Baker SP, Frank KL, Lynch AJL, Hultgren SJ, Kitten T, Lemos JA. “Manganese acquisition is essential for virulence of Enterococcus faecalis.” PLoS Pathog. 2018 Sep;14(9):e1007102.
Colomer-Winter C, Gaca AO, Lemos JA. “Association of metal homeostasis and (p)ppGpp regulation in the pathophysiology of Enterococcus faecalis.” Infect. Immun. 2017 Jul;85(7):e00260-17.
Gaca AO, Kudrin P, Colomer-Winter C, Beljantseva J, Liu K, Anderson B, Wang JD, Rejman D, Potrykus K, Cashel M, Hauryliuk V, Lemos JA. “From (p)ppGpp to (pp)pGpp: Characterization of regulatory effects of pGpp synthesized by the Small Alarmone Synthetase of Enterococcus faecalis.” J. Bacteriol. 2015
Gaca AO, Colomer-Winter C, Lemos JA. “Many means to a common end: the intricacies of (p)ppGpp metabolism and its control of bacterial homeostasis.” Mini-review. J. Bacteriol. 2015.
Frank KL, Colomer-Winter C, Grindle SM, Lemos JA, Schlievert PM, Dunny GM. “Transcriptome analysis of Enterococcus faecalis during mammalian infection shows cells undergo adaptation and exist in a Stringent Response state.” PLoS One. 2014 Dec 29;9(12):e115839.