Alexander Miethke
2 protocols

Swetha Kapil Cincinnati Childrens Hospital Medical Ce Cincinnati
1 protocol

Srikar Pasula Cincinnati Childrens Hospital Medical Ce Cincinnati
1 protocol

Gregory Tiao
1 protocol
Alexandros Alexandratos National and Kapodistrian University of Athens
64 protocols

Avinash Pandey CIMMYT-BISA
3 protocols

Brahma Mulugu Brahma Mulugu
5 protocols

Gal Haimovich Weizmann Institute of Science Rehovot
122 protocols

Reviewer
Alexander Miethke
  • Research associate, Cincinnati Childrens Hospital Cincinnati
Research focus
  • Immunology
    Liver regeneration
    Purinergic signalling
    Pharmacology
    NALD
    IBD
    Biliary Atresia
    Cholestatic liver diseases (PSC/PBC)
    Autoimmune Hepatitis
    Hepatocellular Carcinoma
    Colangiocarcinoma
    Cancer Biology
    Cardiovascular Biology
  • 2 Author merit

Education

PhD, University of Bern, 2016

Lab information

Alexander Miethke
Gastroenterology, Hepatology and Nutrition
http://centerlink.cchmc.org/directory?q=kudira&start=0&site=cdf70737-6d80-4393-8d51-483c7a3f48f2

Publications

2 Protocols published
Isolation of Liver Mononuclear Cells from a Cholestatic Mice for Single Cell or Single Nuclei Sequencing
Authors:  Ramesh Kudira, Srikar Pasula, Shwetha Kapil and Alexander Miethke, date: 05/05/2022, view: 71, Q&A: 0

Cholestasis develops as a consequence of impaired bile formation, secretion, and flow from the liver to the duodenum, causing retention of bile in the body. Cholestasis is classified as intra or extrahepatic cholangitis, primary biliary cholangitis

...
Isolation and Culturing Primary Cholangiocytes from Mouse Liver

Cholangiocytes are epithelial cells lining the intrahepatic and extrahepatic bile ducts. Cholangiocytes perform key physiological functions in the liver. Bile synthesized by hepatocytes is secreted into bile canaliculi, further stored in the

...
12 Protocols reviewed
A Combinatorial in-silico, in-vitro and in-vivo Approach to Quantitatively Study Peptide Induced MHC Stability
Authors:  Roman Sarkar, Yashu Sharma, Ayush Jain, Azeez Tehseen, Sudhakar Singh and Sharvan Sehrawat, date: 12/20/2021, view: 1012, Q&A: 0

Here, we describe a combinatorial approach in reverse vaccinology to identify immunogenic class I major histocompatibility complex (MHC) displayed epitopes derived from a morbillivirus named pestes des petits ruminants (PPRV). The protocol describes

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Transient yet Robust Expression of Proteins in the Mouse Liver via Intravenous Injection of Lipid Nanoparticle-encapsulated Nucleoside-modified mRNA

With the recent availability of the SARS-CoV-2 mRNA-based vaccines, public attention has been drawn to this new technology and how it may be applied to other indications. Temporal activation of key hepatic regenerative pathways can induce liver

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