Education
PhD, University of Bern, 2016
Lab information
Alexander MiethkeGastroenterology, Hepatology and Nutritionhttp://centerlink.cchmc.org/directory?q=kudira&start=0&site=cdf70737-6d80-4393-8d51-483c7a3f48f2
Publications
Cholestasis develops as a consequence of impaired bile formation, secretion, and flow from the liver to the duodenum, causing retention of bile in the body. Cholestasis is classified as intra or extrahepatic cholangitis, primary biliary cholangitis
Cholangiocytes are epithelial cells lining the intrahepatic and extrahepatic bile ducts. Cholangiocytes perform key physiological functions in the liver. Bile synthesized by hepatocytes is secreted into bile canaliculi, further stored in the
Here, we describe a combinatorial approach in reverse vaccinology to identify immunogenic class I major histocompatibility complex (MHC) displayed epitopes derived from a morbillivirus named pestes des petits ruminants (PPRV). The protocol describes
With the recent availability of the SARS-CoV-2 mRNA-based vaccines, public attention has been drawn to this new technology and how it may be applied to other indications. Temporal activation of key hepatic regenerative pathways can induce liver