Alessandro Didonna East Carolina University
77 protocols

Chen Huei Leo Singapore University of Technology & Design
1 protocol

Jia Li SRI International
51 protocols

Laura Campisi Icahn School of Medicine at Mount Sinai
8 protocols

Sonal Arvind Patel
  • Research scientist, Fusion Pharmaceuticals
Research focus
  • Molecular biology
  • Obesity; aging; circadian clock; adipose tissue; metabolism; type 2 diabetes; Immuno-oncology


Ph.D., Cleveland State University, 2016

Lab information

Dr. John Valliant


 Khapre RV, Patel SA, Kondratova AA, Chaudhary A, Velingkaar N, Antoch MP, Kondratov RV, Metabolic clock generates nutrient anticipation rhythms in mTOR signaling. Aging 2014 Aug; 6(8):675-89.
 Khapre RV, Kondratova AA, Patel S, Yuliya Dubrovsky, Wrobel M, Antoch MP, and Kondratov RV, BMAL1-dependent regulation of the mTOR signaling pathway delays aging. Aging 2014 Jan; 6(1):48-5.
 Patel SA, Velingkaar N, Kondratov RV, Transcriptional control of antioxidant defense by the circadian clock, Antioxidants & Redox Signaling 2014 Jun 20; 20(18):2997-3006.
 Patel SA, Chaudhari A, Gupta R, Velingkaar N, Kondratov RV, Calorie restriction-mediated lifespan extension by the clock protein BMAL1, FASEB J. 2016 Apr;30(4):1634-42. doi: 10.1096/fj.15-282475. Epub 2015 Dec 23.
 Patel SA., Velingkaar N., Makwana K., Chaudhari A., Kondratov RV., Calorie restriction regulates circadian clock genes expression through BMAL1 and CRY1 dependent mechanisms, Sci Rep. 2016 May 12;6:25970. doi: 10.1038/srep25970.
 Majumdar T., Dhar J., Patel S., Kondratov R., Barik S., Circadian transcription factor BMAL1 provides innate immunity against select RNA viruses, Innate Immun. 2017 Feb;23(2):147-154. doi: 10.1177/1753425916681075. Epub 2016 Dec 5.
 Chaudhari A., Gupta R., Patel SA., Velingkaar N., Kondratov RV., Cryptochromes regulate IGF-1 production and signaling through control JAK2 dependent STAT5B phosphorylation, Mol Biol Cell. 2017 Mar 15;28(6):834-842. doi: 10.1091/mbc. E16-08-0624. Epub 2017 Jan 18.
 Makwana K., Patel SA., Velingkaar N., Ebron JS., Shukla GC., and Kondratov RV., Aging and calorie restriction regulate the expression of miR-125a-5p and its target genes Stat3, Casp2 and Stard13, Aging (Albany NY). 2017 Jul 31;9(7):1825-1843. doi: 10.18632/aging.101270.
 Astafevy A., Patel SA., and Kondratov RV., Calorie restriction effects on circadian rhythms in gene expression are sex dependent, Sci Rep. 2017 Aug 29;7(1):9716. doi: 10.1038/s41598-017-09289-9.
 Sonal A. Patel, and Roman V. Kondratov, “Clock at the Core of Cancer Development”, Biology 2021, 10(2), 150;
 Wen Dai, Mayank Choubey, Sonal Patel and Lale Ozcan, “Adipocyte CaMKII deficiency improves obesity-associated glucose intolerance” (submitted in Molecular Metabolism)
8 Protocols reviewed
Flow Cytometric Characterization of Macrophages Infected in vitro with Salmonella enterica Serovar Typhimurium Expressing Red Fluorescent Protein

Macrophages are important for host defense against intracellular pathogens like Salmonella and can be differentiated into two major subtypes. M1 macrophages, which are pro-inflammatory and induce antimicrobial immune effector mechanisms, including

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In vivo Imaging of Calcium Activities from Pancreatic β-cells in Zebrafish Embryos Using Spinning-disc Confocal and Two-photon Light-sheet Microscopy
Authors:  Jia Zhao, Shenghui Liang, Yiwen Zhao, Weijian Zong, Elisa Tran, Liangyi Chen and Yanmei Liu, date: 12/05/2021, view: 1743, Q&A: 0

Visualizing the function of pancreatic β-cells in vivo has been a long-sought goal for β-cell researchers. Unlike imaging of β-cells in mammalian species with conventional positron emission tomography and single-photon emission

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