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Caccin, P., Scorzeto, M., Damiano, N., Marin, O., Megighian, A. and Montecucco, C. (2015). The synaptotagmin juxtamembrane domain is involved in neuroexocytosis. FEBS Open Bio 5: 388-396.
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Bercsenyi, K., Schmieg, N., Bryson, J. B., Wallace, M., Caccin, P., Golding, M., Zanotti, G., Greensmith, L., Nischt, R. and Schiavo, G. (2014). Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus. Science 346(6213): 1118-1123.
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Vono, M., Taccone, M., Caccin, P., Gallotta, M., Donvito, G., Falzoni, S., Palmieri, E., Pallaoro, M., Rappuoli, R., Di Virgilio, F., De Gregorio, E., Montecucco, C. and Seubert, A. (2013). The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination. Proc Natl Acad Sci U S A 110(52): 21095-21100.
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Fernandez, J., Caccin, P., Koster, G., Lomonte, B., Gutierrez, J. M., Montecucco, C. and Postle, A. D. (2013). Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A(2) myotoxins--distinct mechanisms of action. FEBS J 280(16): 3878-3886.
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Caccin, P., Pellegatti, P., Fernandez, J., Vono, M., Cintra-Francischinelli, M., Lomonte, B., Gutierrez, J. M., Di Virgilio, F. and Montecucco, C. (2013). Why myotoxin-containing snake venoms possess powerful nucleotidases? Biochem Biophys Res Commun 430(4): 1289-1293.
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Eleopra, R., Montecucco, C., Devigili, G., Lettieri, C., Rinaldo, S., Verriello, L., Pirazzini, M., Caccin, P. and Rossetto, O. (2013). Botulinum neurotoxin serotype D is poorly effective in humans: an in vivo electrophysiological study. Clin Neurophysiol 124(5): 999-1004.
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Zornetta, I., Caccin, P., Fernandez, J., Lomonte, B., Gutierrez, J. M. and Montecucco, C. (2012). Envenomations by Bothrops and Crotalus snakes induce the release of mitochondrial alarmins. PLoS Negl Trop Dis 6(2): e1526.
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Silva-Cardoso, L., Caccin, P., Magnabosco, A., Patron, M., Targino, M., Fuly, A., Oliveira, G. A., Pereira, M. H., do Carmo, M., Souza, A. S., Silva-Neto, M. A., Montecucco, C. and Atella, G. C. (2010). Paralytic activity of lysophosphatidylcholine from saliva of the waterbug Belostoma anurum. J Exp Biol 213(Pt 19): 3305-3310.
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Cintra-Francischinelli, M., Caccin, P., Chiavegato, A., Pizzo, P., Carmignoto, G., Angulo, Y., Lomonte, B., Gutierrez, J. M. and Montecucco, C. (2010). Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain. Proc Natl Acad Sci U S A 107(32): 14140-14145.
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Caccin, P., Magnabosco, A., Tedesco, E., Silva-Cardoso, L., Atella, G. C. and Montecucco, C. (2010). Lysophospholipids are evolutionary ancient venom components. Toxicon 56(8): 1525-1527.
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Tedesco, E., Rigoni, M., Caccin, P., Grishin, E., Rossetto, O. and Montecucco, C. (2009). Calcium overload in nerve terminals of cultured neurons intoxicated by alpha-latrotoxin and snake PLA2 neurotoxins. Toxicon 54(2): 138-144.
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Caccin, P., Rossetto, O. and Montecucco, C. (2009). Neurotoxicity of inverted-cone shaped lipids. Neurotoxicology 30(2): 174-181.
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Montecucco, C., Rossetto, O., Caccin, P., Rigoni, M., Carli, L., Morbiato, L., Muraro, L. and Paoli, M. (2009). Different mechanisms of inhibition of nerve terminals by botulinum and snake presynaptic neurotoxins. Toxicon 54(5): 561-564.
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Rigoni, M., Paoli, M., Milanesi, E., Caccin, P., Rasola, A., Bernardi, P. and Montecucco, C. (2008). Snake phospholipase A2 neurotoxins enter neurons, bind specifically to mitochondria, and open their transition pores. J Biol Chem 283(49): 34013-34020.
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Rigoni, M., Pizzo, P., Schiavo, G., Weston, A. E., Zatti, G., Caccin, P., Rossetto, O., Pozzan, T. and Montecucco, C. (2007). Calcium influx and mitochondrial alterations at synapses exposed to snake neurotoxins or their phospholipid hydrolysis products. J Biol Chem 282(15): 11238-11245.
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Megighian, A., Rigoni, M., Caccin, P., Zordan, M. A. and Montecucco, C. (2007). A lysolecithin/fatty acid mixture promotes and then blocks neurotransmitter release at the Drosophila melanogaster larval neuromuscular junction. Neurosci Lett 416(1): 6-11.
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Verderio, C., Grumelli, C., Raiteri, L., Coco, S., Paluzzi, S., Caccin, P., Rossetto, O., Bonanno, G., Montecucco, C. and Matteoli, M. (2007). Traffic of botulinum toxins A and E in excitatory and inhibitory neurons. Traffic 8(2): 142-153.
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Caccin, P., Rigoni, M., Bisceglie, A., Rossetto, O. and Montecucco, C. (2006). Reversible skeletal neuromuscular paralysis induced by different lysophospholipids. FEBS Lett 580(27): 6317-6321.
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Rigoni, M., Caccin, P., Gschmeissner, S., Koster, G., Postle, A. D., Rossetto, O., Schiavo, G. and Montecucco, C. (2005). Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures. Science 310(5754): 1678-1680.
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Caccin, P., Rossetto, O., Rigoni, M., Johnson, E., Schiavo, G. and Montecucco, C. (2003). VAMP/synaptobrevin cleavage by tetanus and botulinum neurotoxins is strongly enhanced by acidic liposomes. FEBS Lett 542(1-3): 132-136.
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Rossetto, O., Caccin, P., Rigoni, M., Tonello, F., Bortoletto, N., Stevens, R. C. and Montecucco, C. (2001). Active-site mutagenesis of tetanus neurotoxin implicates TYR-375 and GLU-271 in metalloproteolytic activity. Toxicon 39(8): 1151-1159.