Simona Giunta
  • Research associate, The Rockefeller University, USA
Research focus
  • Cancer biology
  • Centromere; Genome Stability; Repetitive DNA
  • 1 Author merit


Ph.D., The University of Cambridge, 2011

Lab information

Hironori Funabiki Laboratory


- HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome.
Jenness C, Giunta S, Müller MM, Kimura H, Muir TW, Funabiki H
Proc Natl Acad Sci U S A. Accepted.

- ZSCAN10 expression corrects the genomic instability of iPSCs from aged donors.
Skamagki M, Correia C, Yeung P, Baslan T, Beck S, Zhang C, Ross CA, Dang L, Liu Z, Giunta S, Chang TP, Wang J, Ananthanarayanan A, Bohndorf M, Bosbach B, Adjaye J, Funabiki H, Kim J, Lowe S, Collins JJ, Lu CW, Li H, Zhao R, Kim K.
Nat Cell Biol. 2017 Sep;19(9):1037-1048. doi: 10.1038/ncb3598. Epub 2017 Aug 28.
PMID: 28846095

- Integrity of the human centromere DNA repeats is protected by CENP-A, CENP-C, and CENP-T.
Giunta S, Funabiki H.
Proc Natl Acad Sci U S A. 2017 Feb 21;114(8):1928-1933. doi: 10.1073/pnas.1615133114. Epub 2017 Feb 6.
PMID: 28167779

- γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies.
Valdiglesias V, Giunta S, Fenech M, Neri M, Bonassi S.
Mutat Res. 2013 Jul-Sep;753(1):24-40. doi: 10.1016/j.mrrev.2013.02.001. Epub 2013 Feb 13. Review.
PMID: 23416207

- Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events.
Giunta S, Jackson SP.
Cell Cycle. 2011 Apr 15;10(8):1215-21. Epub 2011 Apr 15.
PMID: 21412056

- DNA damage signaling in response to double-strand breaks during mitosis.
Giunta S, Belotserkovskaya R, Jackson SP.
J Cell Biol. 2010 Jul 26;190(2):197-207. doi: 10.1083/jcb.200911156.
PMID: 20660628

- A gust of WNT: analysis of the canonical WNT pathway.
Giunta S.
Acta Biomed. 2009;80(3):187-99. Review.
PMID: 20578410
1 Protocol published
Centromere Chromosome Orientation Fluorescent in situ Hybridization (Cen-CO-FISH) Detects Sister Chromatid Exchange at the Centromere in Human Cells
Author:  Simona Giunta, date: 04/05/2018, view: 7530, Q&A: 0
Human centromeres are composed of large tandem arrays of repetitive alpha satellite DNA, which are often sites of aberrant rearrangement in cancers (Mitelman et al., 1997; Padilla-Nash et al., 2001). To date, annotation of the ...
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