Education
Ph.D., University of Hawaii, USA, 1981
Current position
University Distinguished Professor, Pathology, University of Kansas Medical Center, USA
Publications (since 2011)
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Soares, M. J., Iqbal, K. and Kozai, K. (2017). Hypoxia and placental development. Birth Defects Res 109(17): 1309-1329.
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Bu, P., Yagi, S., Shiota, K., Alam, S. M. K., Vivian, J. L., Wolfe, M. W., Rumi, M. A. K., Chakraborty, D., Kubota, K., Dhakal, P. and Soares, M. J. (2017). Origin of a rapidly evolving homeostatic control system programming testis function. J Endocrinol 234(2): 217-232.
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Rumi, M. A. K., Singh, P., Roby, K. F., Zhao, X., Iqbal, K., Ratri, A., Lei, T., Cui, W., Borosha, S., Dhakal, P., Kubota, K., Chakraborty, D., Vivian, J. L., Wolfe, M. W. and Soares, M. J. (2017). Defining the Role of Estrogen Receptor beta in the Regulation of Female Fertility. Endocrinology 158(7): 2330-2343.
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Chhibber, A., Woody, S. K., Karim Rumi, M. A., Soares, M. J. and Zhao, L. (2017). Estrogen receptor beta deficiency impairs BDNF-5-HT2A signaling in the hippocampus of female brain: A possible mechanism for menopausal depression. Psychoneuroendocrinology 82: 107-116.
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McGreal, S. R., Rumi, K., Soares, M. J., Woolbright, B. L., Jaeschke, H. and Apte, U. (2017). Disruption of Estrogen Receptor Alpha in Rats Results in Faster Initiation of Compensatory Regeneration Despite Higher Liver Injury After Carbon Tetrachloride Treatment. Int J Toxicol 36(3): 199-206.
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Dhakal, P. and Soares, M. J. (2017). Single-step PCR-based genetic sex determination of rat tissues and cells. Biotechniques 62(5): 232-233.
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Renaud, S. J., Scott, R. L., Chakraborty, D., Rumi, M. A. and Soares, M. J. (2017). Natural killer-cell deficiency alters placental development in rats. Biol Reprod 96(1): 145-158.
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Chakraborty, D., Cui, W., Rosario, G. X., Scott, R. L., Dhakal, P., Renaud, S. J., Tachibana, M., Rumi, M. A., Mason, C. W., Krieg, A. J. and Soares, M. J. (2016). HIF-KDM3A-MMP12 regulatory circuit ensures trophoblast plasticity and placental adaptations to hypoxia. Proc Natl Acad Sci U S A 113(46): E7212-E7221.
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Soares, M. J. and Vivian, J. L. (2016). Tipping the balance toward trophoblast development. Proc Natl Acad Sci U S A 113(19): 5144-5146.
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Bu, P., Alam, S. M., Dhakal, P., Vivian, J. L. and Soares, M. J. (2016). A Prolactin Family Paralog Regulates Placental Adaptations to a Physiological Stressor. Biol Reprod 94(5): 107.
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Imakawa, K., Dhakal, P., Kubota, K., Kusama, K., Chakraborty, D., Karim Rumi, M. A. and Soares, M. J. (2016). CITED2 modulation of trophoblast cell differentiation: insights from global transcriptome analysis. Reproduction 151(5): 509-516.
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Kubota, K., Cui, W., Dhakal, P., Wolfe, M. W., Rumi, M. A., Vivian, J. L., Roby, K. F. and Soares, M. J. (2016). Rethinking progesterone regulation of female reproductive cyclicity. Proc Natl Acad Sci U S A 113(15): 4212-4217.
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Ilekis, J. V., Tsilou, E., Fisher, S., Abrahams, V. M., Soares, M. J., Cross, J. C., Zamudio, S., Illsley, N. P., Myatt, L., Colvis, C., Costantine, M. M., Haas, D. M., Sadovsky, Y., Weiner, C., Rytting, E. and Bidwell, G. (2016). Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development. Am J Obstet Gynecol 215(1 Suppl): S1-S46.
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Dhakal, P., Rumi, M. A., Kubota, K., Chakraborty, D., Chien, J., Roby, K. F. and Soares, M. J. (2015). Neonatal Progesterone Programs Adult Uterine Responses to Progesterone and Susceptibility to Uterine Dysfunction. Endocrinology 156(10): 3791-3803.
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Renaud, S. J., Chakraborty, D., Mason, C. W., Rumi, M. A., Vivian, J. L. and Soares, M. J. (2015). OVO-like 1 regulates progenitor cell fate in human trophoblast development. Proc Natl Acad Sci U S A 112(45): E6175-6184.
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Kubota, K., Kent, L. N., Rumi, M. A., Roby, K. F. and Soares, M. J. (2015). Dynamic Regulation of AP-1 Transcriptional Complexes Directs Trophoblast Differentiation. Mol Cell Biol 35(18): 3163-3177.
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Alam, S. M., Konno, T. and Soares, M. J. (2015). Identification of target genes for a prolactin family paralog in mouse decidua. Reproduction 149(6): 625-632.
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PrabhuDas, M., Bonney, E., Caron, K., Dey, S., Erlebacher, A., Fazleabas, A., Fisher, S., Golos, T., Matzuk, M., McCune, J. M., Mor, G., Schulz, L., Soares, M., Spencer, T., Strominger, J., Way, S. S. and Yoshinaga, K. (2015). Immune mechanisms at the maternal-fetal interface: perspectives and challenges. Nat Immunol 16(4): 328-334.
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Soares, M. J., Chakraborty, D., Kubota, K., Renaud, S. J. and Rumi, M. A. (2014). Adaptive mechanisms controlling uterine spiral artery remodeling during the establishment of pregnancy. Int J Dev Biol 58(2-4): 247-259.
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Rumi, M. A., Dhakal, P., Kubota, K., Chakraborty, D., Lei, T., Larson, M. A., Wolfe, M. W., Roby, K. F., Vivian, J. L. and Soares, M. J. (2014). Generation of Esr1-knockout rats using zinc finger nuclease-mediated genome editing. Endocrinology 155(5): 1991-1999.
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Renaud, S. J., Kubota, K., Rumi, M. A. and Soares, M. J. (2014). The FOS transcription factor family differentially controls trophoblast migration and invasion. J Biol Chem 289(8): 5025-5039.
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Soares, M. J. (2014). Embryo implantation - coordination of maternal and embryonic adaptations. Int J Dev Biol 58(2-4): 71-74.
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Holloway, A. C., Salomon, A., Soares, M. J., Garnier, V., Raha, S., Sergent, F., Nicholson, C. J., Feige, J. J., Benharouga, M. and Alfaidy, N. (2014). Characterization of the adverse effects of nicotine on placental development: in vivo and in vitro studies. Am J Physiol Endocrinol Metab 306(4): E443-456.
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Kwok, S. C., Chakraborty, D., Soares, M. J. and Dai, G. (2013). Relative expression of proprotein convertases in rat ovaries during pregnancy. J Ovarian Res 6(1): 91.
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Imakawa, K., Nakagawa, S. and Kusama, K. (2016). Placental Development and Endogenous Retroviruses. Uirusu 66(1): 1-10.
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Hong, J., He, H., Bui, P., Ryba-White, B., Rumi, M. A., Soares, M. J., Dutta, D., Paul, S., Kawamata, M., Ochiya, T., Ying, Q. L., Rajanahalli, P. and Weiss, M. L. (2013). A focused microarray for screening rat embryonic stem cell lines. Stem Cells Dev 22(3): 431-443.
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Chakraborty, D., Rumi, M. A. and Soares, M. J. (2012). NK cells, hypoxia and trophoblast cell differentiation. Cell Cycle 11(13): 2427-2430.
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Shankar, K., Zhong, Y., Kang, P., Blackburn, M. L., Soares, M. J., Badger, T. M. and Gomez-Acevedo, H. (2012). RNA-seq analysis of the functional compartments within the rat placentation site. Endocrinology 153(4): 1999-2011.
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Soares, M. J., Chakraborty, D., Karim Rumi, M. A., Konno, T. and Renaud, S. J. (2012). Rat placentation: an experimental model for investigating the hemochorial maternal-fetal interface. Placenta 33(4): 233-243.
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Hayakawa, K., Nakanishi, M. O., Ohgane, J., Tanaka, S., Hirosawa, M., Soares, M. J., Yagi, S. and Shiota, K. (2012). Bridging sequence diversity and tissue-specific expression by DNA methylation in genes of the mouse prolactin superfamily. Mamm Genome 23(5-6): 336-345.
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Kent, L. N., Ohboshi, S. and Soares, M. J. (2012). Akt1 and insulin-like growth factor 2 (Igf2) regulate placentation and fetal/postnatal development. Int J Dev Biol 56(4): 255-261.
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Asanoma, K., Kubota, K., Chakraborty, D., Renaud, S. J., Wake, N., Fukushima, K., Soares, M. J. and Rumi, M. A. (2012). SATB homeobox proteins regulate trophoblast stem cell renewal and differentiation. J Biol Chem 287(3): 2257-2268.
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Soares, M. J., Chakraborty, D., Renaud, S. J., Kubota, K., Bu, P., Konno, T. and Rumi, M. A. (2012). Regulatory pathways controlling the endovascular invasive trophoblast cell lineage. J Reprod Dev 58(3): 283-287.
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Kent, L. N., Rumi, M. A., Kubota, K., Lee, D. S. and Soares, M. J. (2011). FOSL1 is integral to establishing the maternal-fetal interface. Mol Cell Biol 31(23): 4801-4813.
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Chakraborty, D., Rumi, M. A., Konno, T. and Soares, M. J. (2011). Natural killer cells direct hemochorial placentation by regulating hypoxia-inducible factor dependent trophoblast lineage decisions. Proc Natl Acad Sci U S A 108(39): 16295-16300.
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Konno, T., Rempel, L. A., Rumi, M. A., Graham, A. R., Asanoma, K., Renaud, S. J. and Soares, M. J. (2011). Chromosome-substituted rat strains provide insights into the genetics of placentation. Physiol Genomics 43(15): 930-941.
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Dai, G., Bustamante, J. J., Zou, Y., Myronovych, A., Bao, Q., Kumar, S. and Soares, M. J. (2011). Maternal hepatic growth response to pregnancy in the mouse. Exp Biol Med (Maywood) 236(11): 1322-1332.
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Al-Khan, A., Aye, I. L., Barsoum, I., Borbely, A., Cebral, E., Cerchi, G., Clifton, V. L., Collins, S., Cotechini, T., Davey, A., Flores-Martin, J., Fournier, T., Franchi, A. M., Fretes, R. E., Graham, C. H., Godbole, G., Hansson, S. R., Headley, P. L., Ibarra, C., Jawerbaum, A., Kemmerling, U., Kudo, Y., Lala, P. K., Lassance, L., Lewis, R. M., Menkhorst, E., Morris, C., Nobuzane, T., Ramos, G., Rote, N., Saffery, R., Salafia, C., Sarr, D., Schneider, H., Sibley, C., Singh, A. T., Sivasubramaniyam, T. S., Soares, M. J., Vaughan, O., Zamudio, S. and Lash, G. E. (2011). IFPA Meeting 2010 Workshops Report II: Placental pathology; trophoblast invasion; fetal sex; parasites and the placenta; decidua and embryonic or fetal loss; trophoblast differentiation and syncytialisation. Placenta 32 Suppl 2: S90-99.
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Asanoma, K., Rumi, M. A., Kent, L. N., Chakraborty, D., Renaud, S. J., Wake, N., Lee, D. S., Kubota, K. and Soares, M. J. (2011). FGF4-dependent stem cells derived from rat blastocysts differentiate along the trophoblast lineage. Dev Biol 351(1): 110-119.
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Renaud, S. J., Karim Rumi, M. A. and Soares, M. J. (2011). Review: Genetic manipulation of the rodent placenta. Placenta 32 Suppl 2: S130-135.
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Renaud, S. J. and Soares, M. J. (2011). Strategies for investigating hemochorial placentation. In: Gupta, R. C. (Ed). Handbook of Reproductive and Developmental Toxicology, Elsevier, pp: 1029-1038.
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Lafontaine, L., Chaudhry, P., Lafleur, M. J., Van Themsche, C., Soares, M. J. and Asselin, E. (2011). Transforming growth factor Beta regulates proliferation and invasion of rat placental cell lines. Biol Reprod 84(3): 553-559.