David J Loane
  • Department of Anesthesiology, Center for Shock, Trauma, and Anesthesiology Research (STAR), University of Maryland School of Medicine, United States, United States,
Research fields
  • Neuroscience
Personal information


Ph.D., University of Bristol, United Kingdom, 2004

Current position

Associate Professor, Department of Anesthesiology, University of Maryland School of Medicine, USA


  1. Google Scholar: https://scholar.google.com/citations?user=dznbdfYAAAAJ&hl=en&oi=sra
  2. Villapol, S., Loane, D. J. and Burns, M. P. (2017). Sexual dimorphism in the inflammatory response to traumatic brain injury. Glia 65(9): 1423-1438.
  3. Barrett, J. P., Henry, R. J., Villapol, S., Stoica, B. A., Kumar, A., Burns, M. P., Faden, A. I. and Loane, D. J. (2017). NOX2 deficiency alters macrophage phenotype through an IL-10/STAT3 dependent mechanism: implications for traumatic brain injury. J Neuroinflammation 14(1): 65.
  4. Kumar, A., Alvarez-Croda, D. M., Stoica, B. A., Faden, A. I. and Loane, D. J. (2016). Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury. J Neurotrauma 33(19): 1732-1750.
  5. Kumar, A., Barrett, J. P., Alvarez-Croda, D. M., Stoica, B. A., Faden, A. I. and Loane, D. J. (2016). NOX2 drives M1-like microglial/macrophage activation and neurodegeneration following experimental traumatic brain injury. Brain Behav Immun 58: 291-309.
  6. Loane, D. J., Kumar, A., Stoica, B. A., Cabatbat, R. and Faden, A. I. (2014). Progressive neurodegeneration after experimental brain trauma: association with chronic microglial activation. J Neuropathol Exp Neurol 73(1): 14-29.
  7. Kumar, A., Stoica, B. A., Sabirzhanov, B., Burns, M. P., Faden, A. I. and Loane, D. J. (2013). Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states. Neurobiol Aging 34(5): 1397-1411.
  8. Kumar, A. and Loane, D. J. (2012). Neuroinflammation after traumatic brain injury: opportunities for therapeutic intervention. Brain Behav Immun 26(8): 1191-1201.
  9. Loane, D. J., Pocivavsek, A., Moussa, C. E., Thompson, R., Matsuoka, Y., Faden, A. I., Rebeck, G. W. and Burns, M. P. (2009). Amyloid precursor protein secretases as therapeutic targets for traumatic brain injury. Nat Med 15(4): 377-379.
  10. Loane, D. J., Deighan, B. F., Clarke, R. M., Griffin, R. J., Lynch, A. M. and Lynch, M. A. (2009). Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain. Neurobiol Aging 30(6): 920-931.
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.