Tinghai Xu
  • Faculty, Saint Louis Universtiy
Research fields
  • Biochemistry, Cell Biology, Molecular Biology, Cryo-EM, Structural Biology
Personal information

Education

PHD, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China, 2017

Lab information

Edward A. Doisy Department of Biochemistry and Molecular Biology at Saint Louis University School of Medicine, St. Louis, MO

Research focus

My laboratory is dedicated to investigating the intricate interplay among DNA methylation, histone modification, and chromatin remodeling, and their profound implications for human diseases. Through a multidisciplinary approach that incorporates structural and cell biological techniques, we aim to decode the complex crosstalk between these epigenetic mechanisms and their pivotal role in disease pathogenesis. My group is committed to leveraging our deep understanding of the mechanisms and regulations of DNA methylation on chromatin to develop innovative therapeutic interventions for the treatment of cancers. In addition, my laboratory is actively interested in exploring chromatin- related protein complexes.

Publications

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