Education
Ph.D, ETH Zürich, Switzerland, 2000
Current position
Principal Investigator, Institute of Human Genetics, Montpellier, CNRS, France
Publications
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Ciabrelli, F., Comoglio, F., Fellous, S., Bonev, B., Ninova, M., Szabo, Q., Xuereb, A., Klopp, C., Aravin, A., Paro, R., Bantignies, F. and Cavalli, G. (2017). Stable Polycomb-dependent transgenerational inheritance of chromatin states in Drosophila. Nat Genet.
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Loubiere, V., Delest, A., Thomas, A., Bonev, B., Schuettengruber, B., Sati, S., Martinez, A. M. and Cavalli, G. (2016). Coordinate redeployment of PRC1 proteins suppresses tumor formation during Drosophila development. Nat Genet 48(11): 1436-1442.
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Bonev, B. and Cavalli, G. (2016). Organization and function of the 3D genome. Nat Rev Genet 17(11): 661-678.
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Sexton, T. and Cavalli, G. (2015). The role of chromosome domains in shaping the functional genome. Cell 160(6): 1049-1059.
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Gonzalez, I., Mateos-Langerak, J., Thomas, A., Cheutin, T. and Cavalli, G. (2014). Identification of regulators of the three-dimensional polycomb organization by a microscopy-based genome-wide RNAi screen. Mol Cell 54(3): 485-499.
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Iovino, N., Ciabrelli, F. and Cavalli, G. (2013). PRC2 controls Drosophila oocyte cell fate by repressing cell cycle genes. Dev Cell 26(4): 431-439.
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Cavalli, G. (2012). Molecular biology. EZH2 goes solo. Science 338(6113): 1430-1431.
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Sexton, T., Yaffe, E., Kenigsberg, E., Bantignies, F., Leblanc, B., Hoichman, M., Parrinello, H., Tanay, A. and Cavalli, G. (2012). Three-dimensional folding and functional organization principles of the Drosophila genome. Cell 148(3): 458-472.
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Bantignies, F., Roure, V., Comet, I., Leblanc, B., Schuettengruber, B., Bonnet, J., Tixier, V., Mas, A. and Cavalli, G. (2011). Polycomb-dependent regulatory contacts between distant Hox loci in Drosophila. Cell 144(2): 214-226.
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Schuettengruber, B., Martinez, A. M., Iovino, N. and Cavalli, G. (2011). Trithorax group proteins: switching genes on and keeping them active. Nat Rev Mol Cell Biol 12(12): 799-814.
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Martinez, A. M., Schuettengruber, B., Sakr, S., Janic, A., Gonzalez, C. and Cavalli, G. (2009). Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling. Nat Genet 41(10): 1076-1082.
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Schuettengruber, B., Ganapathi, M., Leblanc, B., Portoso, M., Jaschek, R., Tolhuis, B., van Lohuizen, M., Tanay, A. and Cavalli, G. (2009). Functional anatomy of polycomb and trithorax chromatin landscapes in Drosophila embryos. PLoS Biol 7(1): e13.
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Schuettengruber, B., Chourrout, D., Vervoort, M., Leblanc, B. and Cavalli, G. (2007). Genome regulation by polycomb and trithorax proteins. Cell 128(4): 735-745.
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Comet, I., Savitskaya, E., Schuettengruber, B., Negre, N., Lavrov, S., Parshikov, A., Juge, F., Gracheva, E., Georgiev, P. and Cavalli, G. (2006). PRE-mediated bypass of two Su(Hw) insulators targets PcG proteins to a downstream promoter. Dev Cell 11(1): 117-124.
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Negre, N., Hennetin, J., Sun, L. V., Lavrov, S., Bellis, M., White, K. P. and Cavalli, G. (2006). Chromosomal distribution of PcG proteins during Drosophila development. PLoS Biol 4(6): e170.
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Grimaud, C., Bantignies, F., Pal-Bhadra, M., Ghana, P., Bhadra, U. and Cavalli, G. (2006). RNAi components are required for nuclear clustering of Polycomb group response elements. Cell 124(5): 957-971.
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Martinez, A. M., Colomb, S., Dejardin, J., Bantignies, F. and Cavalli, G. (2006). Polycomb group-dependent Cyclin A repression in Drosophila. Genes Dev 20(4): 501-513.
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Dejardin, J., Rappailles, A., Cuvier, O., Grimaud, C., Decoville, M., Locker, D. and Cavalli, G. (2005). Recruitment of Drosophila Polycomb group proteins to chromatin by DSP1. Nature 434(7032): 533-538.
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Bantignies, F., Grimaud, C., Lavrov, S., Gabut, M. and Cavalli, G. (2003). Inheritance of Polycomb-dependent chromosomal interactions in Drosophila. Genes Dev 17(19): 2406-2420.
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Cavalli, G. and Paro, R. (1999). Epigenetic inheritance of active chromatin after removal of the main transactivator. Science 286(5441): 955-958.
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Cavalli, G. and Paro, R. (1998). The Drosophila Fab-7 chromosomal element conveys epigenetic inheritance during mitosis and meiosis. Cell 93(4): 505-518.