Volker Patzel Microbiology & Immunology, National University of Singapore, Singapore
2 protocols

Xiaoou Jiang
  • Microbiology & Immunology, National University of Singapore, Singapore
Research focus
  • Molecular biology
  • 2 Author merit


Ph.D, National University of Singapore, Singapore, 2015

Current position

Research Fellow, Microbiology and Immunology, National University of Singapore, Singapore


  1. Jiang, X., Yu, H., Teo, C. R., Tan, G. S., Goh, S. C., Patel, P., Chua, Y. K., Hameed, N. B., Bertoletti, A. and Patzel, V. (2016). Advanced Design of Dumbbell-shaped Genetic Minimal Vectors Improves Non-coding and Coding RNA Expression. Mol Ther 24(9): 1581-1591.
  2. Yu, H., Jiang, X., Tan, K. T., Hang, L. and Patzel, V. (2015). Efficient production of superior dumbbell-shaped DNA minimal vectors for small hairpin RNA expression. Nucleic Acids Res 43(18): e120.
  3. Tan, K. S., Choi, H., Jiang, X., Yin, L., Seet, J. E., Patzel, V., Engelward, B. P. and Chow, V. T. (2014). Micro-RNAs in regenerating lungs: an integrative systems biology analysis of murine influenza pneumonia. BMC Genomics 15: 587.
  4. Jung, U., Jiang, X., Kaufmann, S. H. and Patzel, V. (2013). A universal TaqMan-based RT-PCR protocol for cost-efficient detection of small noncoding RNA. RNA 19(12): 1864-1873.
  5. Liu, A. M., Wong, K. F., Jiang, X., Qiao, Y. and Luk, J. M. (2012). Regulators of mammalian Hippo pathway in cancer. Biochim Biophys Acta 1826(2): 357-364.
  6. Cao, D. X., Li, Z. J., Jiang, X. O., Lum, Y. L., Khin, E., Lee, N. P., Wu, G. H. and Luk, J. M. (2012). Osteopontin as potential biomarker and therapeutic target in gastric and liver cancers. World J Gastroenterol 18(30): 3923-3930.
2 Protocols published
Advanced Design of Minimalistic Dumbbell-shaped Gene Expression Vectors
Authors:  Xiaoou Jiang and Volker Patzel, date: 08/05/2017, view: 8781, Q&A: 0
Minimal DNA vectors exclusively comprising therapeutically relevant sequences hold great promise for the development of novel therapeutic regimen. Dumbbell-shaped vectors represent non-viral non-integrating DNA minimal vectors which have entered an ...
Formation of Minimised Hairpin Template-transcribing Dumbbell Vectors for Small RNA Expression
Authors:  Xiaoou Jiang and Volker Patzel, date: 06/05/2017, view: 8643, Q&A: 0
A major barrier for using non-viral vectors for gene therapy is the short duration of transgene expression in postmitotic tissues. Previous studies showed transgene expression from conventional plasmid fell to sub-therapeutic level shortly after ...
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