Hélène Tourrière
  • Institute of Human Genetics, CNRS UMR 9002 and University of Montpellier, Equipe labéllisée LIGUE 2017, France
Research fields
  • Cancer biology
Personal information


Ph.D in Biochemestry and Moelcular Biology , Montpellier, France, 2002

Current position

Staff scientist , Institute of Humans Genetics, CNRS-UMR 9002, France


  1. Bianco, J. N., Poli, J., Saksouk, J., Bacal, J., Silva, M. J., Yoshida, K., Lin, Y. L., Tourriere, H., Lengronne, A. and Pasero, P. (2012). Analysis of DNA replication profiles in budding yeast and mammalian cells using DNA combing. Methods 57(2): 149-157.
  2. Lana, E., Megarbane, A., Tourriere, H., Sarda, P., Lefranc, G., Claustres, M. and De Sario, A. (2012). DNA replication is altered in Immunodeficiency Centromeric instability Facial anomalies (ICF) cells carrying DNMT3B mutations. Eur J Hum Genet 20(10): 1044-1050.
  3. Giannattasio, M., Follonier, C., Tourriere, H., Puddu, F., Lazzaro, F., Pasero, P., Lopes, M., Plevani, P. and Muzi-Falconi, M. (2010). Exo1 competes with repair synthesis, converts NER intermediates to long ssDNA gaps, and promotes checkpoint activation. Mol Cell 40(1): 50-62.
  4. Tuduri, S., Crabbe, L., Tourriere, H., Coquelle, A. and Pasero, P. (2010). Does interference between replication and transcription contribute to genomic instability in cancer cells? Cell Cycle 9(10): 1886-1892.
  5. Tuduri, S., Tourriere, H. and Pasero, P. (2010). Defining replication origin efficiency using DNA fiber assays. Chromosome Res 18(1): 91-102.
  6. Tuduri, S., Crabbe, L., Conti, C., Tourriere, H., Holtgreve-Grez, H., Jauch, A., Pantesco, V., De Vos, J., Thomas, A., Theillet, C., Pommier, Y., Tazi, J., Coquelle, A. and Pasero, P. (2009). Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription. Nat Cell Biol 11(11): 1315-1324.
  7. Tourriere, H. and Pasero, P. (2007). Maintenance of fork integrity at damaged DNA and natural pause sites. DNA Repair (Amst) 6(7): 900-913.
  8. Tourriere, H., Versini, G., Cordon-Preciado, V., Alabert, C. and Pasero, P. (2005). Mrc1 and Tof1 promote replication fork progression and recovery independently of Rad53. Mol Cell 19(5): 699-706.
  9. Zekri, L., Chebli, K., Tourriere, H., Nielsen, F. C., Hansen, T. V., Rami, A. and Tazi, J. (2005). Control of fetal growth and neonatal survival by the RasGAP-associated endoribonuclease G3BP. Mol Cell Biol 25(19): 8703-8716.
  10. Cande, C., Vahsen, N., Metivier, D., Tourriere, H., Chebli, K., Garrido, C., Tazi, J. and Kroemer, G. (2004). Regulation of cytoplasmic stress granules by apoptosis-inducing factor. J Cell Sci 117(Pt 19): 4461-4468.
  11. Tourriere, H., Chebli, K., Zekri, L., Courselaud, B., Blanchard, J. M., Bertrand, E. and Tazi, J. (2003). The RasGAP-associated endoribonuclease G3BP assembles stress granules. J Cell Biol 160(6): 823-831.
  12. Tourriere, H., Chebli, K. and Tazi, J. (2002). mRNA degradation machines in eukaryotic cells. Biochimie 84(8): 821-837.
  13. Tourriere, H., Gallouzi, I. E., Chebli, K., Capony, J. P., Mouaikel, J., van der Geer, P. and Tazi, J. (2001). RasGAP-associated endoribonuclease G3Bp: selective RNA degradation and phosphorylation-dependent localization. Mol Cell Biol 21(22): 7747-7760.
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