Jalaj Gupta
  • Faculty, Stem Cell Research Center (SCRC), Sanjay Gandhi Post Graduate Institute of Medical Sciences (SGPGIMS), Lucknow
Research fields
  • Cancer biology
Personal information



Research focus

Animal models, Cancer biology, Colorectal cancer, intestinal stem cells, cell plasticity


1. Gandhi, S., Gupta, J., and Tripathi, P. P. (2019). The Curious Case of Human Hippocampal Neurogenesis. ACS Chem Neurosci 10, 1131-1132.
2. Tripathi P.P., Arami H., Banga I., Gupta J., and Gandhi S. (2018). Cell Penetrating Peptides in Preclinical and Clinical Cancer Diagnosis and Therapy. Oncotarget 9(98):37252-37267.
3. Canli, Ö., Nicolas A.M.*, Gupta, J. *, Finkelmeier, F.*, Goncharova, O., Pesic, M., Neumann, T., Horst, D., Löwer, M., Sahin, U., and Greten, F.R. (2017). Myeloid cell-derived reactive oxygen species induce epithelial mutagenesis. Cancer Cell. 32, 869-883.
* These authors contributed equally
(Cover article for December, 2017 issue of Cancer Cell, preview of this article was published in Cancer Cell. 2017 32(6):727-729)
4. van Wijk, S. J. L., Fricke, F., Herhaus, L., Gupta, J., Hotte, K., Pampaloni, F., Grumati, P., Kaulich, M., Sou, Y. S., Komatsu, M., et al. (2017). Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-kappaB and restricts bacterial proliferation. Nat Microbiol 2, 17066.
5. Diamanti, M. A.*, Gupta, J.*, Bennecke, M., De Oliveira, T., Ramakrishnan, M., Braczynski, A. K., Richter, B., Beli, P., Hu, Y., Saleh, M., et al. (2017). IKKalpha controls ATG16L1 degradation to prevent ER stress during inflammation. J Exp Med 214, 423-437.
*equal contribution
6. Igea, A., Gupta, J., and Nebreda, A. R. (2015). Targeting of non-oncogene addiction. Aging (Albany NY) 7(8):525-6.
7. Gupta, J., and Nebreda, A.R. (2015). Roles of p38 MAPK in mouse models of inflammatory diseases and cancer. FEBS J 282(10):1841-1857.
8. Gupta, J*., Igea, A*, Papaioannou, M., Lopez-Casas, P.P., Llonch, E., Hidalgo, M., Gorgoulis, V.G., and Nebreda, A.R. (2015). Pharmacological inhibition of p38 MAPK reduces tumor growth in patient-derived xenografts from colon tumors. Oncotarget 6(11):8539-8551.
*equal contribution
9. Gupta, J., del Barco Barrantes, I., Igea, A., Sakellariou, S., Gorgoulis, V. G., and Nebreda, A. R. (2014). Dual function of p38 MAPK in colon cancer: suppression of colitis-associated tumor initiation but requirement for cancer cell survival. Cancer Cell 25, 484-500.
10. Llopis, A., Salvador, N., Ercilla, A., Guaita-Esteruelas, S., Barrantes Idel, B., Gupta, J., Gaestel, M., Davis, R. J., Nebreda, A. R., and Agell, N. (2012). The stress-activated protein kinases p38alpha/beta and JNK1/2 cooperate with Chk1 to inhibit mitotic entry upon DNA replication arrest. Cell Cycle 11, 3627-3637.
11. Nagarajan, M., Kumar, N., Nishanth, G., Haribaskar, R., Paranthaman, K., Gupta, J., Mishra, M., Vaidhegi, R., Kumar, S., and Ranjan, A. K. (2009). Microsatellite markers of water buffalo, Bubalus bubalis--development, characterisation and linkage disequilibrium studies. BMC Genetics 10, 68.
12. Ramirez, J. L., Salazar, M. F., Gupta, J., Sanchez, J. M., Taron, M., Sanchez-Ronco, M., Alberola, V., and De las Penas, R. (2006). Methylation patterns and chemosensitivity in NSCLC. Advances in Experimental Medicine and Biology 587, 195-209.
13. Kumar, S., Gupta, J., Kumar, N., Dikshit, K., Navani, N., Jain, P., and Nagarajan, M. (2006). Genetic variation and relationships among eight Indian riverine buffalo breeds. Molecular Ecology 15, 593-600.
14. Thangaraj, K., Sridhar, V., Kivisild, T., Reddy, A. G., Chaubey, G., Singh, V. K., Kaur, S., Agarawal, P., Rai, A., Gupta, J., et al. (2005). Different population histories of the Mundari- and Mon-Khmer-speaking Austro-Asiatic tribes inferred from the mtDNA 9-bp deletion/insertion polymorphism in Indian populations. Human Genetics 116, 507-517.
We use cookies on this site to enhance your user experience. By using our website, you are agreeing to allow the storage of cookies on your computer.