Emmanuel Orta-Zavalza
  • Faculty, Universidad Autónoma de Ciudad Juárez
Research fields
  • Cell Biology, Immunology, Microbiology, Molecular Biology, Mycology
Personal information


PhD, IPICYT, 2014

Lab information

Our laboratory is interested in unraveling the complex relationship between fungal pathogens and myeloid cells, especially the different types of polarization states of human macrophages. We seek to contribute to education in clinical mycology to help the lagging health system of developing countries for the opportunal diagnosis of fungal infections.

Research focus

Candida, microbiome, immunology, inflammation, mycosis


1. Gutierrez-Escobedo, G., et al., Role of glutathione in the oxidative stress response in the fungal pathogen Candida glabrata. Curr Genet, 2013. 59(3): p. 91-106.
2. Martinez-Jimenez, V., et al., Sir3 Polymorphisms in Candida glabrata clinical isolates. Mycopathologia, 2013. 175(3-4): p. 207-19.
3. Orta-Zavalza, E., et al., Local silencing controls the oxidative stress response and the multidrug resistance in Candida glabrata. Mol Microbiol, 2013. 88(6): p. 1135-48.
4. Peñas, A.D.L., et al., Adherence, virulence and cell wall proteins of Candida glabrata, in The Fungal Cell Wall. 2013, Nova Science Publishers, Inc. p. 143-157.
5. Briones-Martin-Del-Campo, M., et al., The oxidative stress response of the opportunistic fungal pathogen Candida glabrata. Rev Iberoam Micol, 2014. 31(1): p. 67-71.
6. Briones-Martin-del-Campo, M., et al., The superoxide dismutases of Candida glabrata protect against oxidative damage and are required for lysine biosynthesis, DNA integrity and chronological life survival. Microbiology, 2015. 161(Pt 2): p. 300-10.
7. Izquierdo, E., et al., Reshaping of Human Macrophage Polarization through Modulation of Glucose Catabolic Pathways. J Immunol, 2015. 195(5): p. 2442-51.
8. Juarez-Cepeda, J., et al., The EPA2 adhesin encoding gene is responsive to oxidative stress in the opportunistic fungal pathogen Candida glabrata. Curr Genet, 2015. 61(4): p. 529-44.
9. Yanez-Carrillo, P., et al., Expression vectors for C-terminal fusions with fluorescent proteins and epitope tags in Candida glabrata. Fungal Genet Biol, 2015. 80: p. 43-52.
10. Robledo-Marquez, K., et al., Candida glabrata encodes a longer variant of the mating type (MAT) alpha2 gene in the mating type-like MTL3 locus, which can form homodimers. FEMS Yeast Res, 2016. 16(7).
11. Cuevas, V.D., et al., MAFB Determines Human Macrophage Anti-Inflammatory Polarization: Relevance for the Pathogenic Mechanisms Operating in Multicentric Carpotarsal Osteolysis. J Immunol, 2017. 198(5): p. 2070-2081.
12. Hernández-Carrillo, J.G., et al., Evaluation of the effectivity of reuterin in pectin edible coatings to extend the shelf-life of strawberries during cold storage. Food Packaging and Shelf Life, 2021. 30: p. 100760.
13. Cuevas, V.D., et al., The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent. J Innate Immun, 2022. 14(3): p. 243-256.
14. Vazquez-Franco, N., et al., Candida glabrata Hst1-Rfm1-Sum1 complex evolved to control virulence-related genes. Fungal Genet Biol, 2022. 159: p. 103656.
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