Xuenong Zou
  • Department of Spinal Surgery, the First Affiliated Hospital of Sun Yat-sen University, China
Research focus
  • Stem cell
Personal information


Ph.D in Orthopaedics, University Hospital of Aarhus, Denmark

Current position

Director of Orthopaedic Research Institute, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China


  1. Luo, J., Cao, K., Yu, T., Li, L., Huang, S., Gong, M., Cao, C. and Zou, X. (2016). Comparison of Posterior Lumbar Interbody Fusion versus Posterolateral Fusion for the Treatment of Isthmic Spondylolithesis. Clin Spine Surg.

  2. Zhou, Z., Wei, F., Huang, S., Gao, M., Li, H., Stodkilde-Jorgensen, H., Lind, M., Bunger, C. and Zou, X. (2015). In Vivo Magnetic Resonance Imaging Evaluation of Porous Tantalum Interbody Fusion Devices in a Porcine Spinal Arthrodesis Model. Spine (Phila Pa 1976) 40(19): 1471-1478.

  3. Wa, Q., Gao, M., Dai, X., Yu, T., Zhou, Z., Xu, D. and Zou, X. (2015). Induction of chondrogenic differentiation of mouse embryonic mesenchymal stem cells through an in vitro pellet model. Cell Biol Int 39(6): 657-665.

  4. Wei, F., Pan, X., Zhou, Z., Cui, S., Zhong, R., Wang, L., Gao, M., Chen, N., Liang, Z., Zou, X., Huang, S. and Liu, S. (2015). Anterior-only stabilization using cage versus plating with bone autograft for the treatment of type II/IIA Hangman's fracture combined with intervertebral disc injury. J Orthop Surg Res 10: 33.

  5. Tang, Y., Jacobi, A., Vater, C., Zou, L., Zou, X. and Stiehler, M. (2015). Icariin promotes angiogenic differentiation and prevents oxidative stress-induced autophagy in endothelial progenitor cells. Stem Cells 33(6): 1863-1877.

  6. Luo, J., Cao, K., Huang, S., Li, L., Yu, T., Cao, C., Zhong, R., Gong, M., Zhou, Z. and Zou, X. (2015). Comparison of anterior approach versus posterior approach for the treatment of multilevel cervical spondylotic myelopathy. Eur Spine J 24(8): 1621-1630.

  7. Luo, J., Huang, S., Gong, M., Li, L., Yu, T. and Zou, X. (2015). Two-level anterior cervical discectomy and fusion using self-locking stand-alone polyetheretherketone cages with two anchoring clips placed in the upper and lower vertebrae, respectively. Eur J Orthop Surg Traumatol 25 Suppl 1: S147-153.

  8. Wei, F., Zhong, R., Wang, L., Zhou, Z., Pan, X., Cui, S., Sun, H., Zou, X., Gao, M., Jiang, B., Chen, W., Zhuang, W., Sun, H. and Liu, S. (2015). Pingyangmycin-induced in vivo lumbar disc degeneration model of rhesus monkeys. Spine (Phila Pa 1976) 40(4): E199-210.

  9. Luo, J., Gong, M., Huang, S., Yu, T. and Zou, X. (2015). Incidence of adjacent segment degeneration in cervical disc arthroplasty versus anterior cervical decompression and fusion meta-analysis of prospective studies. Arch Orthop Trauma Surg 135(2): 155-160.

  10. Tang, Y., Jacobi, A., Vater, C., Zou, X. and Stiehler, M. (2014). Salvianolic acid B protects human endothelial progenitor cells against oxidative stress-mediated dysfunction by modulating Akt/mTOR/4EBP1, p38 MAPK/ATF2, and ERK1/2 signaling pathways. Biochem Pharmacol 90(1): 34-49.

  11. Tang, Y., Vater, C., Jacobi, A., Liebers, C., Zou, X. and Stiehler, M. (2014). Salidroside exerts angiogenic and cytoprotective effects on human bone marrow-derived endothelial progenitor cells via Akt/mTOR/p70S6K and MAPK signalling pathways. Br J Pharmacol 171(9): 2440-2456.

  12. He, P., Zhu, Q., Zhang, Z., Zou, X. and Xu, D. (2013). Relationship between the tibial mechanical axis and bony anatomical landmarks of the calf and foot as measured on radiographs obtained with a new laser-calibrated position. J Xray Sci Technol 21(4): 497-506.

  13. Chen, D., Li, Y., Zhou, Z., Wu, C., Xing, Y., Zou, X., Tian, W. and Zhang, C. (2013). HIF-1alpha inhibits Wnt signaling pathway by activating Sost expression in osteoblasts. PLoS One 8(6): e65940.

  14. Jacobi, A., Rauh, J., Bernstein, P., Liebers, C., Zou, X. and Stiehler, M. (2013). Comparative analysis of reference gene stability in human mesenchymal stromal cells during osteogenic differentiation. Biotechnol Prog 29(4): 1034-1042.

  15. Zhou, Z., Jiang, B., Zhou, Z., Pan, X., Sun, H., Huang, B., Liang, T., Ringgaard, S. and Zou, X. (2013). Intervertebral disk degeneration: T1rho MR imaging of human and animal models. Radiology 268(2): 492-500.

  16. Huang, S., Peng, L., Tang, Y., Zhang, L., Guo, W., Zou, X. and Peng, X. (2013). Hypoxia of PC-3 prostate cancer cells enhances migration and vasculogenesis in vitro of bone marrow-derived endothelial progenitor cells by secretion of cytokines. Oncol Rep 29(6): 2369-2377.

  17. Chen, M., Hein, S., Le, D. Q., Feng, W., Foss, M., Kjems, J., Besenbacher, F., Zou, X. and Bunger, C. (2013). Free radicals generated by tantalum implants antagonize the cytotoxic effect of doxorubicin. Int J Pharm 448(1): 214-220. 

  18. Ren, D., Wang, M., Guo, W., Zhao, X., Tu, X., Huang, S., Zou, X. and Peng, X. (2013). Wild-type p53 suppresses the epithelial-mesenchymal transition and stemness in PC-3 prostate cancer cells by modulating miR145. Int J Oncol 42(4): 1473-1481.

  19. Zhou, Z., Zhou, Z., Chen, S., Li, H., Zou, L., Ye, J., Ringgaard, S., Bunger, C. and Zou, X. (2012). T1rho-MR imaging technique to distinguish four-layered zonal structure of articular cartilage for detecting early-onset osteoarthritis. J Xray Sci Technol 20(4): 437-446.

  20. Huang, S., Guo, W., Tang, Y., Ren, D., Zou, X. and Peng, X. (2012). miR-143 and miR-145 inhibit stem cell characteristics of PC-3 prostate cancer cells. Oncol Rep 28(5): 1831-1837.

  21. Peng, X., Chen, L., Du, H., Lai, Y., Li, F. and Zou, X. (2011). Malignant transformation of benign intraosseous schwannoma in the cervical spine: a case report with an immunohistochemical study. Int Surg 96(4): 337-344.

  22. Guo, X., Chen, M., Feng, W., Liang, J., Zhao, H., Tian, L., Chao, H. and Zou, X. (2011). Electrostatic self-assembly of multilayer copolymeric membranes on the surface of porous tantalum implants for sustained release of doxorubicin. Int J Nanomedicine 6: 3057-3064.

  23. Peng, X., Guo, W., Liu, T., Wang, X., Tu, X., Xiong, D., Chen, S., Lai, Y., Du, H., Chen, G., Liu, G., Tang, Y., Huang, S. and Zou, X. (2011). Identification of miRs-143 and -145 that is associated with bone metastasis of prostate cancer and involved in the regulation of EMT. PLoS One 6(5): e20341.

  24. Tang, Y., Huang, B., Sun, L., Peng, X., Chen, X. and Zou, X. (2011). Ginkgolide B promotes proliferation and functional activities of bone marrow-derived endothelial progenitor cells: involvement of Akt/eNOS and MAPK/p38 signaling pathways. Eur Cell Mater 21: 459-469.

  25. Peng, X., Chen, L., Wan, Y. and Zou, X. (2011). Treatment of primary basilar invagination by cervical traction and posterior instrumented reduction together with occipitocervical fusion. Spine (Phila Pa 1976) 36(19): 1528-1531.

  26. Chen, M., Le, D. Q., Baatrup, A., Nygaard, J. V., Hein, S., Bjerre, L., Kassem, M., Zou, X. and Bunger, C. (2011). Self-assembled composite matrix in a hierarchical 3-D scaffold for bone tissue engineering. Acta Biomater 7(5): 2244-2255.

  27. Chen, M., Feng, W., Cao, H., Zou, L., Chen, C., Baatrup, A., Nielsen, A. B., Li, H., Kassem, M., Zou, X. and Bunger, C. (2009). A traditional Chinese medicine formula extracts stimulate proliferation and inhibit mineralization of human mesenchymal stem cells in vitro. J Ethnopharmacol 125(1): 75-82.

  28. Zou, X., Zou, L., Foldager, C., Bendtsen, M., Feng, W. and Bunger, C. E. (2009). Different mechanisms of spinal fusion using equine bone protein extract, rhBMP-2 and autograft during the process of anterior lumbar interbody fusion. Biomaterials 30(6): 991-1004.

  29. Zou, X., Zou, L., He, Y. and Bunger, C. (2008). Molecular treatment strategies and surgical reconstruction for metastatic bone diseases. Cancer Treat Rev 34(6): 527-538.

  30. Zou, X., Li, H., Teng, X., Xue, Q., Egund, N., Lind, M. and Bunger, C. (2005). Pedicle screw fixation enhances anterior lumbar interbody fusion with porous tantalum cages: an experimental study in pigs. Spine (Phila Pa 1976) 30(14): E392-399.

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