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John LaCava
  • Faculty, European Research Institute for the Biology of Ageing
Research focus
  • Biochemistry
  • 3 Author merit

Education

Ph.D, University of Edinburgh, Scotland, 2005

Lab information

http://www.macromolecule.fun

3 Protocols published
Identification of RNase-sensitive LINE-1 Ribonucleoprotein Interactions by Differential Affinity Immobilization
Authors:  Hua Jiang, Martin S. Taylor, Kelly R. Molloy, Ilya Altukhov and John LaCava, date: 04/05/2019, view: 3217, Q&A: 0
Long Interspersed Nuclear Element-1 (LINE-1, L1) constitutes a family of autonomous, self-replicating genetic elements known as retrotransposons. Although most are inactive, copious L1 sequences populate the human genome. L1s proliferate in a ...
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RNA Degradation Assay Using RNA Exosome Complexes, Affinity-purified from HEK-293 Cells
Authors:  Michal Domanski and John LaCava, date: 04/20/2017, view: 5980, Q&A: 0
The RNA exosome complex plays a central role in RNA processing and regulated turnover. Present both in cytoplasm and nucleus, the exosome functions through associations with ribonucleases and various adapter proteins (reviewed in [Kilchert et al ...
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