Education

Ph.D in Science, Kumamoto University, Kumamoto, Japan, 2008

Current position

Specially Appointed Assistant Professor, RNA Biofunction, Institute for Genetic Medicine, Hokkaido University, Sapporo, Japan

Publications

1. Mannen, T., Yamashita, S., Tomita, K., Goshima, N. and Hirose, T. (2016). The Sam68 nuclear body is composed of two RNase-sensitive substructures joined by the adaptor HNRNPL. J Cell Biol 214(1): 45-59.
2. Hennig, S., Kong, G., Mannen, T., Sadowska, A., Kobelke, S., Blythe, A., Knott, G. J., Iyer, K. S., Ho, D., Newcombe, E. A., Hosoki, K., Goshima, N., Kawaguchi, T., Hatters, D., Trinkle-Mulcahy, L., Hirose, T., Bond, C. S. and Fox, A. H. (2015). Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles. J Cell Biol 210(4): 529-539.
3. Nishida, K. M., Iwasaki, Y. W., Murota, Y., Nagao, A., Mannen, T., Kato, Y., Siomi, H. and Siomi, M. C. (2015). Respective functions of two distinct Siwi complexes assembled during PIWI-interacting RNA biogenesis in Bombyx germ cells. Cell Rep 10(2): 193-203.
4. Hirose, T. and Mannen, T. (2015). Rapid and efficient elimination of specific nuclear noncoding RNAs in mammalian cells with antisense oligonucleotides. Methods Mol Biol 1206: 149-156.
5. Siomi, M. C., Mannen, T. and Siomi, H. (2010). How does the royal family of Tudor rule the PIWI-interacting RNA pathway?  Genes Dev 24: 636-646. 
6. Mannen, T., Andoh, T. and Tani, T. (2008). Dss1 associating with the proteasome functions in selective nuclear mRNA export in yeast. Biochem Biophys Res Commun 365(4): 664-671.