Daniela Benati
  • Center for Regenerative Medicine “Stephano Ferrari”, Department of Life Sciences, University of Modena and Reggio Emilia, Italy
Research focus
  • Immunology
Personal information


Ph.D in Evolutionary Biology, University of Siena, Italy, 2009

Current position

Postdoctoral Research Fellow, Centre for Regenerative Medicine, University of Modena and Reggio Emilia, Italy


  1. Latella, M. C., Di Salvo, M. T., Cocchiarella, F., Benati, D., Grisendi, G., Comitato, A., Marigo, V. and Recchia, A. (2016). In vivo Editing of the Human Mutant Rhodopsin Gene by Electroporation of Plasmid-based CRISPR/Cas9 in the Mouse Retina. Mol Ther Nucleic Acids 5: e389.
  2. Benati, D., Galperin, M., Lambotte, O., Gras, S., Lim, A., Mukhopadhyay, M., Nouel, A., Campbell, K. A., Lemercier, B., Claireaux, M., Hendou, S., Lechat, P., de Truchis, P., Boufassa, F., Rossjohn, J., Delfraissy, J. F., Arenzana-Seisdedos, F. and Chakrabarti, L. A. (2016). Public T cell receptors confer high-avidity CD4 responses to HIV controllers. J Clin Invest 126(6): 2093-2108.
  3. Bugault, F., Benati, D., Mouthon, L., Landires, I., Rohrlich, P., Pestre, V., Theze, J., Lortholary, O. and Chakrabarti, L. A. (2013). Altered responses to homeostatic cytokines in patients with idiopathic CD4 lymphocytopenia. PLoS One 8(1): e55570.
  4. Vingert, B., Benati, D., Lambotte, O., de Truchis, P., Slama, L., Jeannin, P., Galperin, M., Perez-Patrigeon, S., Boufassa, F., Kwok, W. W., Lemaitre, F., Delfraissy, J. F., Theze, J. and Chakrabarti, L. A. (2012). HIV controllers maintain a population of highly efficient Th1 effector cells in contrast to patients treated in the long term. J Virol 86(19): 10661-10674.
  5. Ferro, M., Savino, M. T., Ortensi, B., Finetti, F., Genovese, L., Masi, G., Ulivieri, C., Benati, D., Pelicci, G. and Baldari, C. T. (2011). The Shc family protein adaptor, Rai, negatively regulates T cell antigen receptor signaling by inhibiting ZAP-70 recruitment and activation. PLoS One 6(12): e29899.
  6. Benati, D., Ferro, M., Savino, M. T., Ulivieri, C., Schiavo, E., Nuccitelli, A., Pasini, F. L. and Baldari, C. T. (2010). Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus. J Leukoc Biol 87(3): 433-442.
  7. Manfredini, F., Benati, D. and Beani, L. (2010). The strepsipteran endoparasite Xenos vesparum alters the immunocompetence of its host, the paper wasp Polistes dominulus. J Insect Physiol 56(3): 253-259.
  8. Ulivieri, C., Fanigliulo, D., Benati, D., Pasini, F. L. and Baldari, C. T. (2008). Simvastatin impairs humoral and cell-mediated immunity in mice by inhibiting lymphocyte homing, T-cell activation and antigen cross-presentation. Eur J Immunol 38(10): 2832-2844.
  9. Benati, D. and Baldari, C. T. (2008). SRC family kinases as potential therapeutic targets for malignancies and immunological disorders. Curr Med Chem 15(12): 1154-1165.
  10. Coluccia, A. M., Vacca, A., Dunach, M., Mologni, L., Redaelli, S., Bustos, V. H., Benati, D., Pinna, L. A. and Gambacorti-Passerini, C. (2007). Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation. EMBO J 26(5): 1456-1466.
  11. Ghittoni, R., Napolitani, G., Benati, D., Ulivieri, C., Patrussi, L., Laghi Pasini, F., Lanzavecchia, A. and Baldari, C. T. (2006). Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases. Eur J Immunol 36(11): 2885-2893.
  12. Coluccia, A. M., Benati, D., Dekhil, H., De Filippo, A., Lan, C. and Gambacorti-Passerini, C. (2006). SKI-606 decreases growth and motility of colorectal cancer cells by preventing pp60(c-Src)-dependent tyrosine phosphorylation of beta-catenin and its nuclear signaling. Cancer Res 66(4): 2279-2286.
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