Matthew L. Albert
  • Cancer Immunology, Genentech, USA
Research fields
  • Immunology
Personal information


Ph.D of Immunology, The Rockefeller University, New York, USA, 1999

Current position

Principal Scientist, Department of Cancer Immunology, Genentech, South San Francisco, California, USA


  1. Urrutia, A., Duffy, D., Rouilly, V., Posseme, C., Djebali, R., Illanes, G., Libri, V., Albaud, B., Gentien, D., Piasecka, B., Hasan, M., Fontes, M., Quintana-Murci, L., Albert, M. L. and Milieu Interieur, C. (2016). Standardized Whole-Blood Transcriptional Profiling Enables the Deconvolution of Complex Induced Immune Responses. Cell Rep 16(10): 2777-2791.
  2. Mounce, B. C., Cesaro, T., Moratorio, G., Hooikaas, P. J., Yakovleva, A., Werneke, S. W., Smith, E. C., Poirier, E. Z., Simon-Loriere, E., Prot, M., Tamietti, C., Vitry, S., Volle, R., Khou, C., Frenkiel, M. P., Sakuntabhai, A., Delpeyroux, F., Pardigon, N., Flamand, M., Barba-Spaeth, G., Lafon, M., Denison, M. R., Albert, M. L. and Vignuzzi, M. (2016). Inhibition of Polyamine Biosynthesis Is a Broad-Spectrum Strategy against RNA Viruses. J Virol 90(21): 9683-9692.
  3. Ploquin, M. J., Madec, Y., Casrouge, A., Huot, N., Passaes, C., Lecuroux, C., Essat, A., Boufassa, F., Jacquelin, B., Jochems, S. P., Petitjean, G., Angin, M., Gartner, K., Garcia-Tellez, T., Noel, N., Booiman, T., Boeser-Nunnink, B. D., Roques, P., Saez-Cirion, A., Vaslin, B., Dereudre-Bosquet, N., Barre-Sinoussi, F., Ghislain, M., Rouzioux, C., Lambotte, O., Albert, M. L., Goujard, C., Kootstra, N., Meyer, L. and Muller-Trutwin, M. C. (2016). Elevated Basal Pre-infection CXCL10 in Plasma and in the Small Intestine after Infection Are Associated with More Rapid HIV/SIV Disease Onset. PLoS Pathog 12(8): e1005774.
  4. Decalf, J., da Silva, R. B., Werneke, S. and Albert, M. L. (2016). Comment on "NRF2 activation by antioxidant antidiabetic agents accelerates tumor metastasis". Sci Transl Med 8(349): 349le341.
  5. Decalf, J., Tarbell, K. V., Casrouge, A., Price, J. D., Linder, G., Mottez, E., Sultanik, P., Mallet, V., Pol, S., Duffy, D. and Albert, M. L. (2016). Inhibition of DPP4 activity in humans establishes its in vivo role in CXCL10 post-translational modification: prospective placebo-controlled clinical studies. EMBO Mol Med 8(6): 679-683.
  6. Sagoo, P., Garcia, Z., Breart, B., Lemaitre, F., Michonneau, D., Albert, M. L., Levy, Y. and Bousso, P. (2016). In vivo imaging of inflammasome activation reveals a subcapsular macrophage burst response that mobilizes innate and adaptive immunity. Nat Med 22(1): 64-71.
  7. Decque, A., Joffre, O., Magalhaes, J. G., Cossec, J. C., Blecher-Gonen, R., Lapaquette, P., Silvin, A., Manel, N., Joubert, P. E., Seeler, J. S., Albert, M. L., Amit, I., Amigorena, S. and Dejean, A. (2016). Sumoylation coordinates the repression of inflammatory and anti-viral gene-expression programs during innate sensing. Nat Immunol 17(2): 140-149.
  8. About, F., Oudot-Mellakh, T., Niay, J., Rabiega, P., Pedergnana, V., Duffy, D., Sultanik, P., Cagnot, C., Carrat, F., Marcellin, P., Zoulim, F., Larrey, D., Hezode, C., Fontaine, H., Bronowicki, J. P., Pol, S., Albert, M. L., Theodorou, I., Cobat, A., Abel, L. and group, A. C. C. s. (2015). Impact of IL28B, APOH and ITPA Polymorphisms on Efficacy and Safety of TVR- or BOC-Based Triple Therapy in Treatment-Experienced HCV-1 Patients with Compensated Cirrhosis from the ANRS CO20-CUPIC Study. PLoS One 10(12): e0145105.
  9. Alanio, C., Nicoli, F., Sultanik, P., Flecken, T., Perot, B., Duffy, D., Bianchi, E., Lim, A., Clave, E., van Buuren, M. M., Schnuriger, A., Johnsson, K., Boussier, J., Garbarg-Chenon, A., Bousquet, L., Mottez, E., Schumacher, T. N., Toubert, A., Appay, V., Heshmati, F., Thimme, R., Pol, S., Mallet, V. and Albert, M. L. (2015). Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients. Elife 4.
  10. Yatim, N., Jusforgues-Saklani, H., Orozco, S., Schulz, O., Barreira da Silva, R., Reis e Sousa, C., Green, D. R., Oberst, A. and Albert, M. L. (2015). RIPK1 and NF-kappaB signaling in dying cells determines cross-priming of CD8(+) T cells. Science 350(6258): 328-334.
  11. Joubert, P. E., Stapleford, K., Guivel-Benhassine, F., Vignuzzi, M., Schwartz, O. and Albert, M. L. (2015). Inhibition of mTORC1 Enhances the Translation of Chikungunya Proteins via the Activation of the MnK/eIF4E Pathway. PLoS Pathog 11(8): e1005091.
  12. Mora-Bau, G., Platt, A. M., van Rooijen, N., Randolph, G. J., Albert, M. L. and Ingersoll, M. A. (2015). Macrophages Subvert Adaptive Immunity to Urinary Tract Infection. PLoS Pathog 11(7): e1005044.
  13. Meissner, E. G., Decalf, J., Casrouge, A., Masur, H., Kottilil, S., Albert, M. L. and Duffy, D. (2015). Dynamic Changes of Post-Translationally Modified Forms of CXCL10 and Soluble DPP4 in HCV Subjects Receiving Interferon-Free Therapy. PLoS One 10(7): e0133236.
  14. Barreira da Silva, R., Laird, M. E., Yatim, N., Fiette, L., Ingersoll, M. A. and Albert, M. L. (2015). Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat Immunol 16(8): 850-858.
  15. Tejera-Alhambra, M., Casrouge, A., de Andres, C., Seyfferth, A., Ramos-Medina, R., Alonso, B., Vega, J., Fernandez-Paredes, L., Albert, M. L. and Sanchez-Ramon, S. (2015). Plasma biomarkers discriminate clinical forms of multiple sclerosis. PLoS One 10(6): e0128952.
  16. Chen, X., Hasan, M., Libri, V., Urrutia, A., Beitz, B., Rouilly, V., Duffy, D., Patin, E., Chalmond, B., Rogge, L., Quintana-Murci, L., Albert, M. L., Schwikowski, B. and Milieu Interieur, C. (2015). Automated flow cytometric analysis across large numbers of samples and cell types. Clin Immunol 157(2): 249-260.
  17. Hasan, M., Beitz, B., Rouilly, V., Libri, V., Urrutia, A., Duffy, D., Cassard, L., Di Santo, J. P., Mottez, E., Quintana-Murci, L., Albert, M. L., Rogge, L. and Milieu Interieur, C. (2015). Semi-automated and standardized cytometric procedures for multi-panel and multi-parametric whole blood immunophenotyping. Clin Immunol 157(2): 261-276.
  18. Thomas, S., Rouilly, V., Patin, E., Alanio, C., Dubois, A., Delval, C., Marquier, L. G., Fauchoux, N., Sayegrih, S., Vray, M., Duffy, D., Quintana-Murci, L., Albert, M. L. and Milieu Interieur, C. (2015). The Milieu Interieur study - an integrative approach for study of human immunological variance. Clin Immunol 157(2): 277-293.
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