Ph.D. in Physiology, McGill University, Canada, 1984
Medical Scientist, Medicine (Division of Neurology), Montreal General Hospital
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Djogo, T., Robins, S. C., Schneider, S., Kryzskaya, D., Liu, X., Mingay, A., Gillon, C. J., Kim, J. H., Storch, K. F., Boehm, U., Bourque, C. W., Stroh, T., Dimou, L. and Kokoeva, M. V. (2016). Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control. Cell Metab 23(5): 797-810.
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Choe, K. Y., Prager-Khoutorsky, M., Farmer, W. T., Murai, K. K. and Bourque, C. W. (2016). Effects of Salt Loading on the Morphology of Astrocytes in the Ventral Glia Limitans of the Rat Supraoptic Nucleus. J Neuroendocrinol 28(4).
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Choe, K. Y., Trudel, E. and Bourque, C. W. (2016). Effects of Salt Loading on the Regulation of Rat Hypothalamic Magnocellular Neurosecretory Cells by Ionotropic GABA and Glycine Receptors. J Neuroendocrinol 28(4).
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Farmer, W. T., Abrahamsson, T., Chierzi, S., Lui, C., Zaelzer, C., Jones, E. V., Bally, B. P., Chen, G. G., Theroux, J. F., Peng, J., Bourque, C. W., Charron, F., Ernst, C., Sjostrom, P. J. and Murai, K. K. (2016). Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling. Science 351(6275): 849-854.
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Zaelzer, C., Hua, P., Prager-Khoutorsky, M., Ciura, S., Voisin, D. L., Liedtke, W. and Bourque, C. W. (2015). DeltaN-TRPV1: A Molecular Co-detector of Body Temperature and Osmotic Stress. Cell Rep 13(1): 23-30.
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Stare, J., Siami, S., Trudel, E., Prager-Khoutorsky, M., Sharshar, T. and Bourque, C. W. (2015). Effects of Peritoneal Sepsis on Rat Central Osmoregulatory Neurons Mediating Thirst and Vasopressin Release. J Neurosci 35(35): 12188-12197.
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Prager-Khoutorsky, M. and Bourque, C. W. (2015). Anatomical organization of the rat organum vasculosum laminae terminalis. Am J Physiol Regul Integr Comp Physiol 309(4): R324-337.
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Prager-Khoutorsky, M. and Bourque, C. W. (2015). Mechanical basis of osmosensory transduction in magnocellular neurosecretory neurones of the rat supraoptic nucleus. J Neuroendocrinol 27(6): 507-515.
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Choe, K. Y., Han, S. Y., Gaub, P., Shell, B., Voisin, D. L., Knapp, B. A., Barker, P. A., Brown, C. H., Cunningham, J. T. and Bourque, C. W. (2015). High salt intake increases blood pressure via BDNF-mediated downregulation of KCC2 and impaired baroreflex inhibition of vasopressin neurons. Neuron 85(3): 549-560.
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Gagnon, A., Walsh, M., Okuda, T., Choe, K. Y., Zaelzer, C. and Bourque, C. W. (2014). Modulation of spike clustering by NMDA receptors and neurotensin in rat supraoptic nucleus neurons. J Physiol 592(19): 4177-4186.
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Prager-Khoutorsky, M., Khoutorsky, A. and Bourque, C. W. (2014). Unique interweaved microtubule scaffold mediates osmosensory transduction via physical interaction with TRPV1. Neuron 83(4): 866-878.
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Stachniak, T. J., Trudel, E. and Bourque, C. W. (2014). Cell-specific retrograde signals mediate antiparallel effects of angiotensin II on osmoreceptor afferents to vasopressin and oxytocin neurons. Cell Rep 8(2): 355-362.
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Robins, S. C., Trudel, E., Rotondi, O., Liu, X., Djogo, T., Kryzskaya, D., Bourque, C. W. and Kokoeva, M. V. (2013). Evidence for NG2-glia derived, adult-born functional neurons in the hypothalamus. PLoS One 8(10): e78236.
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Sudbury, J. R. and Bourque, C. W. (2013). Dynamic and permissive roles of TRPV1 and TRPV4 channels for thermosensation in mouse supraoptic magnocellular neurosecretory neurons. J Neurosci 33(43): 17160-17165.
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Choe, K. Y., Olson, J. E. and Bourque, C. W. (2012). Taurine release by astrocytes modulates osmosensitive glycine receptor tone and excitability in the adult supraoptic nucleus. J Neurosci 32(36): 12518-12527.
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Chierzi, S., Stachniak, T. J., Trudel, E., Bourque, C. W. and Murai, K. K. (2012). Activity maintains structural plasticity of mossy fiber terminals in the hippocampus. Mol Cell Neurosci 50(3-4): 260-271.
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Bourque, C. W., Guilak, F. and Liedtke, W. (2012). A TRP that makes us feel hyper. J Physiol 590(8): 1779-1780.
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Trudel, E. and Bourque, C. W. (2012). Circadian modulation of osmoregulated firing in rat supraoptic nucleus neurones. J Neuroendocrinol 24(4): 577-586.
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Ciura, S., Liedtke, W. and Bourque, C. W. (2011). Hypertonicity sensing in organum vasculosum lamina terminalis neurons: a mechanical process involving TRPV1 but not TRPV4. J Neurosci 31(41): 14669-14676.
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Sudbury, J. R., Ciura, S., Sharif-Naeini, R. and Bourque, C. W. (2010). Osmotic and thermal control of magnocellular neurosecretory neurons--role of an N-terminal variant of trpv1. Eur J Neurosci 32(12): 2022-2030.
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Zhan, Y., Melian, N. Y., Pantoja, M., Haines, N., Ruohola-Baker, H., Bourque, C. W., Rao, Y. and Carbonetto, S. (2010). Dystroglycan and mitochondrial ribosomal protein L34 regulate differentiation in the Drosophila eye. PLoS One 5(5): e10488.
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Trudel, E. and Bourque, C. W. (2010). Central clock excites vasopressin neurons by waking osmosensory afferents during late sleep. Nat Neurosci 13(4): 467-474.
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Prager-Khoutorsky, M. and Bourque, C. W. (2010). Osmosensation in vasopressin neurons: changing actin density to optimize function. Trends Neurosci 33(2): 76-83.