M.D. in Medicine, Harvard Medical School, MA, 1984
M.B.A., Business, Columbia University, NY, 2003
Deane P. and Louise Mitchell Professor; Director, Children’s Surgical Research Laboratories;
Co-Director, Institute of Stem Cell Research and Regenerative Medicine; Director, Program in Regenerative Medicine
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Chan, C. K., Lindau, P., Jiang, W., Chen, J. Y., Zhang, L. F., Chen, C. C., Seita, J., Sahoo, D., Kim, J. B., Lee, A., Park, S., Nag, D., Gong, Y., Kulkarni, S., Luppen, C. A., Theologis, A. A., Wan, D. C., DeBoer, A., Seo, E. Y., Vincent-Tompkins, J. D., Loh, K., Walmsley, G. G., Kraft, D. L., Wu, J. C., Longaker, M. T. and Weissman, I. L. (2013). Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proc Natl Acad Sci U S A 110(31): 12643-12648.
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Levi, B., Hyun, J. S., Montoro, D. T., Lo, D. D., Chan, C. K., Hu, S., Sun, N., Lee, M., Grova, M., Connolly, A. J., Wu, J. C., Gurtner, G. C., Weissman, I. L., Wan, D. C. and Longaker, M. T. (2012). In vivo directed differentiation of pluripotent stem cells for skeletal regeneration. Proc Natl Acad Sci U S A 109(50): 20379-20384.
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Sun, N., Yazawa, M., Liu, J., Han, L., Sanchez-Freire, V., Abilez, O. J., Navarrete, E. G., Hu, S., Wang, L., Lee, A., Pavlovic, A., Lin, S., Chen, R., Hajjar, R. J., Snyder, M. P., Dolmetsch, R. E., Butte, M. J., Ashley, E. A., Longaker, M. T., Robbins, R. C. and Wu, J. C. (2012). Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. Sci Transl Med 4(130): 130ra147.
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Quarto, N., Leonard, B., Li, S., Marchand, M., Anderson, E., Behr, B., Francke, U., Reijo-Pera, R., Chiao, E. and Longaker, M. T. (2012). Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells. Proc Natl Acad Sci U S A 109(1): 215-220.
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Rinkevich, Y., Lindau, P., Ueno, H., Longaker, M. T. and Weissman, I. L. (2011). Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. Nature 476(7361): 409-413.
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Levi, B., Nelson, E. R., Li, S., James, A. W., Hyun, J. S., Montoro, D. T., Lee, M., Glotzbach, J. P., Commons, G. W. and Longaker, M. T. (2011). Dura mater stimulates human adipose-derived stromal cells to undergo bone formation in mouse calvarial defects. Stem Cells 29(8): 1241-1255.
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Levi, B., Wan, D. C., Glotzbach, J. P., Hyun, J., Januszyk, M., Montoro, D., Sorkin, M., James, A. W., Nelson, E. R., Li, S., Quarto, N., Lee, M., Gurtner, G. C. and Longaker, M. T. (2011). CD105 protein depletion enhances human adipose-derived stromal cell osteogenesis through reduction of transforming growth factor beta1 (TGF-beta1) signaling. J Biol Chem 286(45): 39497-39509.
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Kwan, M. D., Sellmyer, M. A., Quarto, N., Ho, A. M., Wandless, T. J. and Longaker, M. T. (2011). Chemical control of FGF-2 release for promoting calvarial healing with adipose stem cells. J Biol Chem 286(13): 11307-11313.
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Jia, F., Wilson, K. D., Sun, N., Gupta, D. M., Huang, M., Li, Z., Panetta, N. J., Chen, Z. Y., Robbins, R. C., Kay, M. A., Longaker, M. T. and Wu, J. C. (2010). A nonviral minicircle vector for deriving human iPS cells. Nat Methods 7(3): 197-199.