Education
Ph.D. in Biophysics, Free University of Berlin, 1991
Habilitation in Biophysics, Humboldt University of Berlin, 1999
Current position
Professor of Theoretical Biophysics, Technical University of Munich, Germany
Publications (selected)
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Pelz, B., Žoldák, G., Zeller, F., Zacharias, M. and Rief, M. (2016). Subnanometre enzyme mechanics probed by single-molecule force spectroscopy. Nat Commun 7: 10848.
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Schindler, C. E., de Vries, S. J. and Zacharias, M. (2015). Fully Blind Peptide-Protein Docking with pepATTRACT. Structure 23(8): 1507-1515.
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de Vries, S. J., Schindler, C. E., Chauvot de Beauchêne, I. and Zacharias, M. (2015). A web interface for easy flexible protein-protein docking with ATTRACT. Biophys J 108(3): 462-465.
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Ostermeir, K. and Zacharias, M. (2014). Hamiltonian replica-exchange simulations with adaptive biasing of peptide backbone and side chain dihedral angles. J Comput Chem 35(2): 150-158.
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Kannan, S. and Zacharias, M. (2014). Role of tryptophan side chain dynamics on the Trp-cage mini-protein folding studied by molecular dynamics simulations. PLoS One 9(2): e88383.
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Braun, N., Zacharias, M., Peschek, J., Kastenmuller, A., Zou, J., Hanzlik, M., Haslbeck, M., Rappsilber, J., Buchner, J. and Weinkauf, S. (2011). Multiple molecular architectures of the eye lens chaperone alphaB-crystallin elucidated by a triple hybrid approach. Proc Natl Acad Sci U S A 108(51): 20491-20496.
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Zeller, F. and Zacharias, M. (2014). Adaptive Biasing Combined with Hamiltonian Replica Exchange to Improve Umbrella Sampling Free Energy Simulations. J Chem Theory Comput 10(2): 703-710.
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Saini, S. K., Ostermeir, K., Ramnarayan, V. R., Schuster, H., Zacharias, M. and Springer, S. (2013). Dipeptides promote folding and peptide binding of MHC class I molecules. Proc Natl Acad Sci U S A 110(38): 15383-15388.