Education
Ph.D. in Cell Biology, Department of Physiology and Biophysics, University of Illinois at Urbana-Champaign, 1994
Current position
Professor in Immunology, School of Biological Sciences, Seoul National University, Seoul, Republic of Korea
Publications (since 2006)
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Choi, J., Ryoo, J., Oh, C., Hwang, S. and Ahn, K. (2015). SAMHD1 specifically restricts retroviruses through its RNase activity. Retrovirology 12: 46.
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Kim, S., Seo, D., Kim, D., Hong, Y., Chang, H., Baek, D., Kim, V. N., Lee, S. and Ahn, K. (2015). Temporal Landscape of MicroRNA-Mediated Host-Virus Crosstalk during Productive Human Cytomegalovirus Infection. Cell Host Microbe 17(6): 838-851.
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Ryoo, J., Choi, J., Oh, C., Kim, S., Seo, M., Kim, S. Y., Seo, D., Kim, J., White, T. E., Brandariz-Nunez, A., Diaz-Griffero, F., Yun, C. H., Hollenbaugh, J. A., Kim, B., Baek, D. and Ahn, K. (2014). The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. Nat Med 20(8): 936-941.
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Lee, S., Song, J., Kim, S., Kim, J., Hong, Y., Kim, Y., Kim, D., Baek, D. and Ahn, K. (2013). Selective degradation of host MicroRNAs by an intergenic HCMV noncoding RNA accelerates virus production. Cell Host Microbe 13(6): 678-690.
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Cho, S., Kim, B. Y., Ahn, K. and Jun, Y. (2013). The C-terminal amino acid of the MHC-I heavy chain is critical for binding to Derlin-1 in human cytomegalovirus US11-induced MHC-I degradation. PLoS One 8(8): e72356.
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Kim, Y., Lee, S.*, Kim, S.*, Kim, D., Ahn, J. H. and Ahn, K. (2012). Human cytomegalovirus clinical strain-specific microRNA miR-UL148D targets the human chemokine RANTES during infection. PLoS Pathog 8(3): e1002577.
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Kim, S., Lee, S., Shin, J., Kim, Y., Evnouchidou, I., Kim, D., Kim, Y. K., Kim, Y. E., Ahn, J. H., Riddell, S. R., Stratikos, E., Kim, V. N. and Ahn, K. (2011). Human cytomegalovirus microRNA miR-US4-1 inhibits CD8(+) T cell responses by targeting the aminopeptidase ERAP1. Nat Immunol 12(10): 984-991.
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Jun, Y. and Ahn, K. (2011). Tmp21, a novel MHC-I interacting protein, preferentially binds to Beta2-microglobulin-free MHC-I heavy chains. BMB Rep 44(6): 369-374.
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Cho, S., Ryoo, J., Jun, Y. and Ahn, K. (2011). Receptor-mediated ER export of human MHC class I molecules is regulated by the C-terminal single amino acid. Traffic 12(1): 42-55.
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Cho, K., Cho, S., Lee, S. O., Oh, C., Kang, K., Ryoo, J., Lee, S., Kang, S. and Ahn, K. (2011). Redox-regulated peptide transfer from the transporter associated with antigen processing to major histocompatibility complex class I molecules by protein disulfide isomerase. Antioxid Redox Signal 15(3): 621-633.
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Lee, S. O., Cho, K., Cho, S., Kim, I., Oh, C. and Ahn, K. (2010). Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation. EMBO J 29(2): 363-375.
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Kim, E., Kwak, H. and Ahn, K. (2009). Cytosolic aminopeptidases influence MHC class I-mediated antigen presentation in an allele-dependent manner. J Immunol 183(11): 7379-7387.
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Lee, S., Park, B., Kang, K. and Ahn, K. (2009). Redox-regulated export of the major histocompatibility complex class I-peptide complexes from the endoplasmic reticulum. Mol Biol Cell 20(14): 3285-3294.
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Kang, K., Park, B., Oh, C., Cho, K. and Ahn, K. (2009). A role for protein disulfide isomerase in the early folding and assembly of MHC class I molecules. Antioxid Redox Signal 11(10): 2553-2561.
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Kim, Y., Kang, K., Kim, I., Lee, Y. J., Oh, C., Ryoo, J., Jeong, E. and Ahn, K. (2009). Molecular mechanisms of MHC class I-antigen processing: redox considerations. Antioxid Redox Signal 11(4): 907-936.
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Kim, Y., Park, B., Cho, S., Shin, J., Cho, K., Jun, Y. and Ahn, K. (2008). Human cytomegalovirus UL18 utilizes US6 for evading the NK and T-cell responses. PLoS Pathog 4(8): e1000123.
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Park, B., Lee, S., Kim, E., Cho, K., Riddell, S. R., Cho, S. and Ahn, K. (2006). Redox regulation facilitates optimal peptide selection by MHC class I during antigen processing. Cell 127(2): 369-382.
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Shin, J., Park, B., Lee, S., Kim, Y., Biegalke, B. J., Kang, S. and Ahn, K. (2006). A short isoform of human cytomegalovirus US3 functions as a dominant negative inhibitor of the full-length form. J Virol 80(11): 5397-5404.