Emanuel Rognoni
  • Department of Molecular Medicine, Max Planck Institute of Biochemistry, Germany
Research focus
  • Cell biology
  • 2 Author merit


Ph.D., the Max-Planck-Institute of Biochemistry, 2014

Current position

Research Associate (Postdoc), Centre for Stem Cells & Regenerative Medicine King's College, London, UK


  1. Rognoni, E., Widmaier, M., Jakobson, M., Ruppert, R., Ussar, S., Katsougkri, D., Bottcher, R. T., Lai-Cheong, J. E., Rifkin, D. B., McGrath, J. A. and Fassler, R. (2014). Kindlin-1 controls Wnt and TGF-beta availability to regulate cutaneous stem cell proliferation. Nat Med 20(4): 350-359.
  2. Fraccaroli, A., Franco, C. A., Rognoni, E., Neto, F., Rehberg, M., Aszodi, A., Wedlich-Soldner, R., Pohl, U., Gerhardt, H. and Montanez, E. (2012). Visualization of endothelial actin cytoskeleton in the mouse retina. PLoS One 7(10): e47488.
  3. Widmaier, M., Rognoni, E., Radovanac, K., Azimifar, S. B. and Fassler, R. (2012). Integrin-linked kinase at a glance. J Cell Sci 125(Pt 8): 1839-1843.
  4. Holzmuller, R., Mantwill, K., Haczek, C., Rognoni, E., Anton, M., Kasajima, A., Weichert, W., Treue, D., Lage, H., Schuster, T., Schlegel, J., Gansbacher, B. and Holm, P. S. (2011). YB-1 dependent virotherapy in combination with temozolomide as a multimodal therapy approach to eradicate malignant glioma. Int J Cancer 129(5): 1265-1276.
  5. Rognoni, E., Widmaier, M., Haczek, C., Mantwill, K., Holzmuller, R., Gansbacher, B., Kolk, A., Schuster, T., Schmid, R. M., Saur, D., Kaszubiak, A., Lage, H. and Holm, P. S. (2009). Adenovirus-based virotherapy enabled by cellular YB-1 expression in vitro and in vivo. Cancer Gene Ther 16(10): 753-763.
  6. Ussar, S., Moser, M., Widmaier, M., Rognoni, E., Harrer, C., Genzel-Boroviczeny, O. and Fassler, R. (2008). Loss of Kindlin-1 causes skin atrophy and lethal neonatal intestinal epithelial dysfunction. PLoS Genet 4(12): e1000289.
2 Protocols published
TGFβ Release Co-culture Assay
Author:  Emanuel Rognoni, date: 12/05/2014, view: 10382, Q&A: 0
TGFβ is a potent cytokine modulating various processes including proliferation, differentiation, ECM synthesis and apoptosis (Siegel and Massague, 2003). Thus in many tissues availability of TGFβ is tightly regulated. TGFβ is secreted as an inactive ...
TGFβ Stimulation Assay
Author:  Emanuel Rognoni, date: 12/05/2014, view: 14114, Q&A: 0
TGFβ is part of a growth factor superfamily which modulates cell growth, differentiation, adhesion, migration, ECM synthesis and apoptosis (Massague, 1998; Siegel and Massague, 2003). Free TGFβ binds to its high affinity TGFβ receptor, a receptor ...
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