Education
Ph.D., Department of Biochemistry, University of Wisconsin at Madison, 1983
Current position
Chief, Laboratory of Enteric and Sexually Transmitted Diseases, CBER/FDA (January 2011 - present)
Publications (since 2005)
Peer reviewed research publications
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Plaut, R. D., Mocca, C. P., Prabhakara, R., Merkel, T. J. and Stibitz, S. (2013). Stably luminescent Staphylococcus aureus clinical strains for use in bioluminescent imaging. PLoS One 8(3): e59232.
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Boulanger, A., Chen, Q., Hinton, D. M. and Stibitz, S. (2013). In vivo phosphorylation dynamics of the Bordetella pertussis virulence-controlling response regulator BvgA. Mol Microbiol 88(1): 156-172.
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Prabhakara, R., Foreman, O., De Pascalis, R., Lee, G. M., Plaut, R. D., Kim, S. Y., Stibitz, S., Elkins, K. L. and Merkel, T. J. (2013). Epicutaneous model of community-acquired Staphylococcus aureus skin infections. Infect Immun 81(4): 1306-1315.
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Verma, A., McNichol, B., Domínguez-Castillo, R. I., Amador-Molina, J. C., Arciniega, J. L., Reiter, K., Meade, B. D., Ngundi, M. M., Stibitz, S. and Burns, D. L. (2013). Use of Site-Directed Mutagenesis To Model the Effects of Spontaneous Deamidation on the Immunogenicity of Bacillus anthracis Protective Antigen. Infection and immunity 81(1): 278-284
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Bishop-Lilly, K. A., Plaut, R. D., Chen, P. E., Akmal, A., Willner, K. M., Butani, A., Dorsey, S., Mokashi, V., Mateczun, A. J., Chapman, C., George, M., Luu, T., Read, T. D., Calendar, R., Stibitz, S. and Sozhamannan, S. (2012). Whole genome sequencing of phage resistant Bacillus anthracis mutants reveals an essential role for cell surface anchoring protein CsaB in phage AP50c adsorption. Virol J 9: 246.
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Plaut, R. D., Kelly, V. K., Lee, G. M., Stibitz, S. and Merkel, T. J. (2012). Dissemination bottleneck in a murine model of inhalational anthrax. Infect Immun 80(9): 3189-3193.
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Tonry, J. H., McNichol, B. A., Ramarao, N., Chertow, D. S., Kim, K. S., Stibitz, S., Schneewind, O., Kashanchi, F., Bailey, C. L. and Popov, S. (2012). Bacillus anthracis protease InhA regulates BslA‐mediated adhesion in human endothelial cells. Cellular Microbiology 14(8): 1219-1230.
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Nicholson, T. L., Brockmeier, S. L., Loving, C. L., Register, K. B., Kehrli, M. E., Stibitz, S. E. and Shore, S. M. (2012). Phenotypic modulation of the virulent Bvg phase is not required for pathogenesis and transmission of Bordetella bronchiseptica in swine. Infection and immunity 80(3): 1025-1036.
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Crawford, M. A., Lowe, D. E., Fisher, D. J., Stibitz, S., Plaut, R. D., Beaber, J. W., Zemansky, J., Mehrad, B., Glomski, I. J. and Strieter, R. M. (2011). Identification of the bacterial protein FtsX as a unique target of chemokine-mediated antimicrobial activity against Bacillus anthracis. Proceedings of the National Academy of Sciences 108(41): 17159-17164.
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Decker, K. B., Chen, Q., Hsieh, M. L., Boucher, P., Stibitz, S. and Hinton, D. M. (2011). Different requirements for sigma Region 4 in BvgA activation of the Bordetella pertussis promoters Pfim3 and PfhaB. J Mol Biol 409(5): 692-709.
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Chen, Q., Decker, K. B., Boucher, P. E., Hinton, D. and Stibitz, S. (2010). Novel architectural features of Bordetella pertussis fimbrial subunit promoters and their activation by the global virulence regulator BvgA. Molecular microbiology 77(5): 1326-1340.
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Inatsuka, C. S., Xu, Q., Vujkovic-Cvijin, I., Wong, S., Stibitz, S., Miller, J. F. and Cotter, P. A. (2010). Pertactin is required for Bordetella species to resist neutrophil-mediated clearance. Infection and immunity 78(7): 2901-2909.
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Cybulski, R. J., Jr., Sanz, P., Alem, F., Stibitz, S., Bull, R. L. and O'Brien, A. D. (2009). Four superoxide dismutases contribute to Bacillus anthracis virulence and provide spores with redundant protection from oxidative stress. Infect Immun 77(1): 274-285.
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Loving, C. L., Khurana, T., Osorio, M., Lee, G. M., Kelly, V. K., Stibitz, S. and Merkel, T. J. (2009). Role of anthrax toxins in dissemination, disease progression, and induction of protective adaptive immunity in the mouse aerosol challenge model. Infect Immun 77(1): 255-265.
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Verma, A., Wagner, L., Stibitz, S., Nguyen, N., Guerengomba, F. and Burns, D. L. (2008). Role of the N-terminal amino acid of Bacillus anthracis lethal factor in lethal toxin cytotoxicity and its effect on the lethal toxin neutralization assay. Clin Vaccine Immunol 15(11): 1737-1741.
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Goebel, E. M., Wolfe, D. N., Elder, K., Stibitz, S. and Harvill, E. T. (2008). O antigen protects Bordetella parapertussis from complement. Infection and immunity 76(4): 1774-1780.
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Brahmbhatt, T. N., Janes, B. K., Stibitz, E. S., Darnell, S. C., Sanz, P., Rasmussen, S. B. and O'Brien, A. D. (2007). Bacillus anthracis exosporium protein BclA affects spore germination, interaction with extracellular matrix proteins, and hydrophobicity. Infection and immunity 75(11): 5233-5239.
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Janes, B. K. and Stibitz, S. (2006). Routine markerless gene replacement in Bacillus anthracis. Infect Immun 74(3): 1949-1953.
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Jones, A. M., Boucher, P. E., Williams, C. L., Stibitz, S. and Cotter, P. A. (2005). Role of BvgA phosphorylation and DNA binding affinity in control of Bvg-mediated phenotypic phase transition in Bordetella pertussis. Mol Microbiol 58(3): 700-713.
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Williams, C. L., Boucher, P. E., Stibitz, S. and Cotter, P. A. (2005). BvgA functions as both an activator and a repressor to control Bvgi phase expression of bipA in Bordetella pertussis. Molecular microbiology 56(1): 175-188.
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Veal-Carr, W. L. and Stibitz, S. (2005). Demonstration of differential virulence gene promoter activation in vivo in Bordetella pertussis using RIVET. Mol Microbiol 55(3): 788-798.
Invited book chapters, reviews, and meeting proceedings
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Decker, K. B., James, T. D., Stibitz, S. and Hinton, D. M. (2012). The Bordetella pertussis model of exquisite gene control by the global transcription factor BvgA. Microbiology 158(Pt 7): 1665-1676.
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Janes, B. K. and Stibitz, S. (2011). Genetic Manipulation Methods in Bacillus anthracis. Bacillus anthracis and Anthrax: 53-66.
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Cotter, P. A. and Stibitz, S. (2007). c-di-GMP-mediated regulation of virulence and biofilm formation. Curr Opin Microbiol 10(1): 17-23.
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Stibitz, S. (2006) The bvgASR locus of Bordetella pertussis. In: C. Locht (ed.) Bordetella Molecular Biology. Horizon Scientific Press.