Education
Ph.D. in Molecular Genetics, Universitè Paris-Sud (XI), Paris France,1989
Current position
Professor of Molecular Microbiology, Faculty of Biology, Department of Botany, University of Athens, Panepistimiopolis 15781, Athens, Greece
Publications
Peer-reviewed articles (since 2008)
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Diallinas, G. (2013). Allopurinol and xanthine use different translocation mechanisms and trajectories in the fungal UapA transporter. Biochimie 95(9): 1755-1764.
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Karachaliou, M., Amillis, S., Evangelinos, M., Kokotos, A. C., Yalelis, V. and Diallinas, G. (2013). The arrestin-like protein ArtA is essential for ubiquitination and endocytosis of the UapA transporter in response to both broad-range and specific signals. Mol Microbiol. 88(2):301-17
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Krypotou, E., Kosti, V., Amillis, S., Myrianthopoulos, V., Mikros, E. and Diallinas, G. Modeling, Substrate Docking and Mutational Analysis Identify Residues essential for the function and specificity of a Eukaryotic Purine-Cytosine NCS1 Transporter. J Biol Chem. 287(44):36792-803.
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Kosti, V., Lambrinidis, G., Myrianthopoulos, V., Diallinas, G. and Mikros, E. (2012). Identification of the substrate recognition and transport pathway in a eukaryotic member of the nucleobase-ascorbate transporter (NAT) family. PLoS One 7(7): e41939.
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Leung, J., Karachaliou, M., Alves, C., Diallinas, G. and Byrne, B. (2010). Expression and purification of a functional uric acid-xanthine transporter (UapA). Protein Expr Purif 72(1): 139-146.
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Takeshita, N., Diallinas, G. and Fischer, R. (2012). The role of flotillin FloA and stomatin StoA in the maintenance of apical sterol-rich membrane domains and polarity in the filamentous fungus Aspergillus nidulans. Mol Microbiol 83(6): 1136-1152.
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Amillis, S., Kosti, V., Pantazopoulou, A., Mikros, E. and Diallinas, G. (2011). Mutational analysis and modeling reveal functionally critical residues in transmembrane segments 1 and 3 of the UapA transporter. J Mol Biol 411(3): 567-580.
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Soares-Silva, I., Sa-Pessoa, J., Myrianthopoulos, V., Mikros, E., Casal, M. and Diallinas, G. (2011). A substrate translocation trajectory in a cytoplasm-facing topological model of the monocarboxylate/H(+) symporter Jen1p. Mol Microbiol 81(3): 805-817.
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Gournas, C., Oestreicher, N., Amillis, S., Diallinas, G. and Scazzocchio, C. (2011). Completing the purine utilisation pathway of Aspergillus nidulans. Fungal Genet Biol 48(8): 840-848.
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Anasontzis, G. E., Zerva, A., Stathopoulou, P. M., Haralampidis, K., Diallinas, G., Karagouni, A. D. and Hatzinikolaou, D. G. (2011). Homologous overexpression of xylanase in Fusarium oxysporum increases ethanol productivity during consolidated bioprocessing (CBP) of lignocellulosics. J Biotechnol 152(1-2): 16-23.
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Bitsikas, V., Karachaliou, M., Gournas, C. and Diallinas, G. (2011). Hypertonic conditions trigger transient plasmolysis, growth arrest and blockage of transporter endocytosis in Aspergillus nidulans and Saccharomyces cerevisiae. Mol Membr Biol 28(1): 54-68.
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Elsen, S., Efthymiou, G., Peteinatos, P., Diallinas, G., Kyritsis, P. and Moulis, J. M. (2010). A bacteria-specific 2[4Fe-4S] ferredoxin is essential in Pseudomonas aeruginosa. BMC Microbiol 10: 271.
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Kosti, V., Papageorgiou, I. and Diallinas, G. (2010). Dynamic elements at both cytoplasmically and extracellularly facing sides of the UapA transporter selectively control the accessibility of substrates to their translocation pathway. J Mol Biol 397(5): 1132-1143.
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Leung, J., Karachaliou, M., Alves, C., Diallinas, G. and Byrne, B. (2010). Expression and purification of a functional uric acid-xanthine transporter (UapA). Protein Expr Purif 72(1): 139-146.
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Conde, A., Diallinas, G., Chaumont, F., Chaves, M. and Geros, H. (2010). Transporters, channels, or simple diffusion? Dogmas, atypical roles and complexity in transport systems. Int J Biochem Cell Biol 42(6): 857-868.
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Gournas, C., Amillis, S., Vlanti, A. and Diallinas, G. (2010). Transport-dependent endocytosis and turnover of a uric acid-xanthine permease. Mol Microbiol 75(1): 246-260.
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Vangelatos, I., Vlachakis, D., Sophianopoulou, V. and Diallinas, G. (2009). Modelling and mutational evidence identify the substrate binding site and functional elements in APC amino acid transporters. Mol Membr Biol 26(5): 356-370.
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Hamari, Z., Amillis, S., Drevet, C., Apostolaki, A., Vagvolgyi, C., Diallinas, G. and Scazzocchio, C. (2009). Convergent evolution and orphan genes in the Fur4p-like family and characterization of a general nucleoside transporter in Aspergillus nidulans. Mol Microbiol 73(1): 43-57.
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Lemuh, N. D., Diallinas, G., Frillingos, S., Mermelekas, G., Karagouni, A. D. and Hatzinikolaou, D. G. (2009). Purification and partial characterization of the xanthine-uric acid transporter (UapA) of Aspergillus nidulans. Protein Expr Purif 63(1): 33-39.
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Diallinas, G. (2008). Biochemistry. An almost-complete movie. Science 322(5908): 1644-1645.
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Diallinas, G. and Gournas, C. (2008). Structure-function relationships in the nucleobase-ascorbate transporter (NAT) family: lessons from model microbial genetic systems. Channels (Austin) 2(5): 363-372.
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Papageorgiou, I., Gournas, C., Vlanti, A., Amillis, S., Pantazopoulou, A. and Diallinas, G. (2008). Specific interdomain synergy in the UapA transporter determines its unique specificity for uric acid among NAT carriers. J Mol Biol 382(5): 1121-1135.
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Gournas, C., Papageorgiou, I. and Diallinas, G. (2008). The nucleobase-ascorbate transporter (NAT) family: genomics, evolution, structure-function relationships and physiological role. Mol Biosyst 4(5): 404-416.
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Vlanti, A. and Diallinas, G. (2008). The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during germination and in reproductive compartments and is downregulated by endocytosis. Mol Microbiol 68(4): 959-977.
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Papageorgiou, I., De Koning, H. P., Soteriadou, K. and Diallinas, G. (2008). Kinetic and mutational analysis of the Trypanosoma brucei NBT1 nucleobase transporter expressed in Saccharomyces cerevisiae reveals structural similarities between ENT and MFS transporters. Int J Parasitol 38(6): 641-653.
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Goudela, S., Reichard, U., Amillis, S. and Diallinas, G. (2008). Characterization and kinetics of the major purine transporters in Aspergillus fumigatus. Fungal Genet Biol 45(4): 459-472.
Chapters in books
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Diallinas, G. (2007). Aspergillus transporters. In “The Aspergilli: Genomics, Medicine, Biotechnology and Research Methods", Goldman, G. and Osmani, S. (eds). CRC press.
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Diallinas, G. (2004). Molecular Modeling of the Interactions of a Purine Transporter with Different Substrate Analogues: A first Step towards the Systematic Development of Antifungal Drugs. Review of Clinical Pharmacology and Pharmacokinetics, International Edition 18 (1), pp. 59.
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Tavoularis, S. N., Tazebay, U., Diallinas, G., Scazzocchio, C., Sophianopoulou, V. (1997). Preliminary studies on structure-function analysis of a major proline transporter (PRNB) of the filamentous fungus Aspergillus nidulans. Amino Acids 13 (1), pp. 31.
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Diallinas, G. and Kanellis, A. K. (1995). Developmntal and ripening regulation of gene expression of phenylpropanoid biosynthetic enzymes in melon fruit. Post-harvest physiology, pathology and technologies for horticultural commodities: Recent Advances. A.Ait-Oubahou abd El-Otmani (eds). 353-360.
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Felenbok, B., Sophianopoulou, V., Mathieu, M., Sequeval, D., Kulmburg, P., Diallinas, G. and Scazzocchio, C. (1989). Regulation of genes involved in the utilisation of carbon sources in Aspergillus nidulans. Procceedings of the EMBO-Alko Workshop on Molecular Biology of Filamentous Fungi, Helsinki 1989, Nevalainen and Pentilla. (eds). Foundation for Biotechnical and Industrial Fermentation Research, 6: 73-83.