Education
Ph.D. in Immunology, UT-Southwestern Medical Center at Dallas, Dallas, TX, 2003
Current Position
Investigator, Department of Immunology, Shanghai Medical College, Fudan University, Shanghai, 200032, China
Publications
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Huang, Y. L., Morales-Rosado, J., Ray, J., Myers,
T. G., Lu, M. and Munford, R. S. Toll-like receptor (TLR) 1/2 and 4 agonists
prolong triglyceride retention in macrophages. Submitted
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Janelsin, B. M., Myles, I. A., Lu, M. and Datta, S.
K. Altered LPS inactivation due to acyloxyacyl hydrolase deficiency in colonic
lamina propria dendritic cells impairs mucosal Th17 immunity.Submitted
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Lu, M., Varley, A. W. and Munford, R. S. (2013). Persistently active microbial
molecules prolong innate immune tolerance in
vivo. PLoS Pathog 9(5): e1003339.
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Lu, M. and
Munford, R. S. (2011). The
transport and inactivation kinetics of bacterial lipopolysaccharide influence
its immunological potency in vivo. J Immunol 187(6): 3314-3320.
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Munford,
R., Lu, M. and Varley, A. (2009). Chapter 2: Kill the
bacteria...and also their messengers? Adv Immunol 103: 29-48.
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Lu, M., Varley, A. W., Ohta, S., Hardwick, J. and
Munford, R. S. (2008). Host
inactivation of bacterial lipopolysaccharide prevents prolonged tolerance
following gram-negative bacterial infection. Cell Host Microbe 4(3):
293-302.
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Shao, B., Lu, M., Katz, S. C., Varley, A. W.,
Hardwick, J., Rogers, T. E., Ojogun, N., Rockey, D. C., Dematteo, R. P. and
Munford, R. S. (2007). A
host lipase detoxifies bacterial lipopolysaccharides in the liver and spleen. J
Biol Chem 282(18): 13726-13735.
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Lu, M., Zhang, M., Takashima, A., Weiss, J.,
Apicella, M. A., Li, X. H., Yuan, D. and Munford, R. S. (2005). Lipopolysaccharide
deacylation by an endogenous lipase controls innate antibody responses to
Gram-negative bacteria. Nat Immunol 6(10): 989-994.
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Feulner, J. A., Lu, M., Shelton, J. M., Zhang, M.,
Richardson, J. A. and Munford, R. S. (2004). Identification of
acyloxyacyl hydrolase, a lipopolysaccharide-detoxifying enzyme, in the murine
urinary tract. Infect Immun 72(6): 3171-3178.
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Lu, M., Zhang, M., Kitchens, R. L., Fosmire, S., Takashima,
A. and Munford, R. S. (2003). Stimulus-dependent
deacylation of bacterial lipopolysaccharide by dendritic cells. J Exp
Med 197(12): 1745-1754.
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Lu, M. and Jiang, W. D. (1996).Pharmacokinetics of Imported Nisoldipine in Chinese Healthy Volunteers. Chinese Journal of Clinical Pharmacology. 12:93-98