Education
Ph.D. in Bio-medical Genetics (Molecular Virology), University of Madras, Madras, India, 1997
Current position
Assistant Professor, Department of Radiology, MIPS, Stanford University, Stanford, CA, USA
Publications (selected from 74 peer-reviewed publications)
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Paulmurugan, R., Tamrazi, A., Massoud, T. F., Katzenellenbogen, J. A. and Gambhir, S. S. (2011). In vitro and in vivo molecular imaging of estrogen receptor alpha and beta homo- and heterodimerization: exploration of new modes of receptor regulation. Mol Endocrinol 25(12): 2029-2040.
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Sekar, T. V., Dhanabalan, A. and Paulmurugan, R. (2011). Imaging cellular receptors in breast cancers: an overview. Curr Pharm Biotechnol 12(4): 508-527.
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Auer, V. J., Bucher, J., Schremmer-Danninger, E., Paulmurugan, R., Maechler, P., Reiser, M. F., Stangl, M. J. and Berger, F. (2011). Non-invasive imaging of ferucarbotran labeled INS-1E cells and rodent islets in vitro and in transplanted diabetic rats. Curr Pharm Biotechnol 12(4): 488-496.
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Ahn, B. C., Ronald, J. A., Kim, Y. I., Katzenberg, R., Singh, A., Paulmurugan, R., Ray, S., Hofmann, L. V. and Gambhir, S. S. (2011). Potent, tumor-specific gene expression in an orthotopic hepatoma rat model using a Survivin-targeted, amplifiable adenoviral vector. Gene Ther 18(6): 606-612.
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Gheysens, O., Chen, I. Y., Rodriguez-Porcel, M., Chan, C., Rasooly, J., Vaerenberg, C., Paulmurugan, R., Willmann, J. K., Deroose, C., Wu, J. and Gambhir, S. S. (2011). Non-invasive bioluminescence imaging of myoblast-mediated hypoxia-inducible factor-1 alpha gene transfer. Mol Imaging Biol 13(6): 1124-1132.
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Thakor, A. S., Paulmurugan, R., Kempen, P., Zavaleta, C., Sinclair, R., Massoud, T. F. and Gambhir, S. S. (2011). Oxidative stress mediates the effects of Raman-active gold nanoparticles in human cells. Small 7(1): 126-136.
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Fan-Minogue, H., Cao, Z., Paulmurugan, R., Chan, C. T., Massoud, T. F., Felsher, D. W. and Gambhir, S. S. (2010). Noninvasive molecular imaging of c-Myc activation in living mice. Proc Natl Acad Sci U S A 107(36): 15892-15897.
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Massoud, T. F., Paulmurugan, R. and Gambhir, S. S. (2010). A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography. Nat Med 16(8): 921-926.
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Chen, I. Y., Gheysens, O., Ray, S., Wang, Q., Padmanabhan, P., Paulmurugan, R., Loening, A. M., Rodriguez-Porcel, M., Willmann, J. K., Sheikh, A. Y., Nielsen, C. H., Hoyt, G., Contag, C. H., Robbins, R. C., Biswal, S., Wu, J. C. and Gambhir, S. S. (2010). Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy. Gene Ther 17(7): 827-838.
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Paulmurugan, R., Padmanabhan, P., Ahn, B. C., Ray, S., Willmann, J. K., Massoud, T. F., Biswal, S. and Gambhir, S. S. (2009). A novel estrogen receptor intramolecular folding-based titratable transgene expression system. Mol Ther 17(10): 1703-1711.
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Willmann, J. K., Paulmurugan, R., Rodriguez-Porcel, M., Stein, W., Brinton, T. J., Connolly, A. J., Nielsen, C. H., Lutz, A. M., Lyons, J., Ikeno, F., Suzuki, Y., Rosenberg, J., Chen, I. Y., Wu, J. C., Yeung, A. C., Yock, P., Robbins, R. C. and Gambhir, S. S. (2009). Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology 252(1): 117-127.
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Ray, S., Paulmurugan, R., Patel, M. R., Ahn, B. C., Wu, L., Carey, M. and Gambhir, S. S. (2008). Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy. Mol Ther 16(11): 1848-1856.
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Paulmurugan, R., Tamrazi, A., Katzenellenbogen, J. A., Katzenellenbogen, B. S. and Gambhir, S. S. (2008). A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action. Mol Endocrinol 22(7): 1552-1564.
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Paulmurugan, R. and Gambhir, S. S. (2007). Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions. Anal Chem 79(6): 2346-2353.
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Paulmurugan, R. and Gambhir, S. S. (2006). An intramolecular folding sensor for imaging estrogen receptor-ligand interactions. Proc Natl Acad Sci U S A 103(43): 15883-15888.
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Paulmurugan, R., Umezawa, Y. and Gambhir, S. S. (2002). Noninvasive imaging of protein-protein interactions in living subjects by using reporter protein complementation and reconstitution strategies. Proc Natl Acad Sci U S A 99(24): 15608-15613.