Michio Nakaya
  • Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Science, Kyushu University, Japan, Japan,
Research fields
  • Immunology
Personal information


Ph.D., Osaka University, Japan

Current position

Associate Professor, Department of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Kyushu University, Japan


  1. Nakaya, M., Watari, K., Tajima, M., Nakaya, T., Matsuda, S., Ohara, H., Nishihara, H., Yamaguchi, H., Hashimoto, A., Nishida, M., Nagasaka, A., Horii, Y., Ono, H., Iribe, G., Inoue, R., Tsuda, M., Inoue, K., Tanaka, A., Kuroda, M., Nagata, S. and Kurose, H. (2017). Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction. J Clin Invest 127(1): 383-401.
  2. Ohba, Y., Nakaya, M., Watari, K., Nagasaka, A. and Kurose, H. (2015). GRK6 phosphorylates IkappaBalpha at Ser(32)/Ser(36) and enhances TNF-alpha-induced inflammation. Biochem Biophys Res Commun 461(2): 307-313.
  3. Watari, K., Nakaya, M., Nishida, M., Kim, K. M. and Kurose, H. (2013). beta-arrestin2 in infiltrated macrophages inhibits excessive inflammation after myocardial infarction. PLoS One 8(7): e68351.
  4. Nakaya, M., et al. (2013). GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance. Nat Commun 4: 1532.
  5. Nakaya, M., Chikura, S., Watari, K., Mizuno, N., Mochinaga, K., Mangmool, S., Koyanagi, S., Ohdo, S., Sato, Y., Ide, T., Nishida, M. and Kurose, H. (2012). Induction of cardiac fibrosis by beta-blocker in G protein-independent and G protein-coupled receptor kinase 5/beta-arrestin2-dependent Signaling pathways. J Biol Chem 287(42): 35669-35677.
  6. Nakaya, M., Kitano, M., Matsuda, M. and Nagata, S. (2008). Spatiotemporal activation of Rac1 for engulfment of apoptotic cells. Proc Natl Acad Sci U S A 105(27): 9198-9203.
  7. Kitano, M., Nakaya, M., et al. (2008). Imaging of Rab5 activity identifies essential regulators for phagosome maturation. Nature 105: 9198-9203.
  8. Makita, N., Kabasawa, Y., Otani, Y., Firman, Sato, J., Hashimoto, M., Nakaya, M., Nishihara, H., Nangaku, M., Kurose, H., Ohwada, T. and Iiri, T. (2013). Attenuated desensitization of beta-adrenergic receptor by water-soluble N-nitrosamines that induce S-nitrosylation without NO release. Circ Res 112(2): 327-334.
  9. Nakaya, M., Tanaka, M., Okabe, Y., Hanayama, R. and Nagata, S. (2006). Opposite effects of rho family GTPases on engulfment of apoptotic cells by macrophages. J Biol Chem 281(13): 8836-8842.
  10. Nakaya, M., Sanada, K. and Fukada, Y. (2003). Spatial and temporal regulation of mitogen-activated protein kinase phosphorylation in the mouse suprachiasmatic nucleus. Biochem Biophys Res Commun 305(3): 494-501.
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