YD
Yali Dou
  • Department of Pathology, University of Michigan, USA
Research fields
  • Stem cell
Reprogram Murine Epiblast Stem Cells by Epigenetic Inhibitors
Authors:  Hui Zhang and Yali Dou, date: 03/05/2017, view: 6549, Q&A: 0
Pluripotent stem cells in the naïve state are highly useful in regenerative medicine and tissue engineering. A robust reprogramming of the primed murine Epiblast Stem Cells (EpiSCs) to naïve pluripotency is feasible via chemical-only approach. This protocol described a method to reprogram murine EpiSCs by MM-401 treatment, which blocks histone H3K4 methylation by MLL1/KMT2A.
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