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Coauthors
Susanna Rosi Brain and Spinal Injury Center, University of California San Francisco, USA
1 protocol

Timothy Jopson Brain and Spinal Injury Center, University of California San Francisco, USA
1 protocol

Karen Krukowski Brain and Spinal Injury Center, University of California San Francisco, USA
1 protocol
Coreviewers
Adler Dillman Nematology, UC Riverside, USA
11 protocols

Amey Redkar Department of Genetics, University of Cordoba
10 protocols

Beatriz Castro Purdue University
3 protocols

Edel Hennessy University of Edinburgh
4 protocols

Editor
Xi Feng
  • Post-Doc, University of California, San Francisco
Research focus
  • Neuroscience
  • Cognitive Neuroscience, Brain Tumor Mircroenvironment
  • 1 Author merit

Education

PhD, Chinese Academy of Sciences

Lab information

Rosi Lab at USCF

Publications

1. *Krukowski, K., *Feng, X., Paladini, MS., Chou, A., Sacramento, K., Gure, K., Riparip, LK., Jones, T., Campbell-Beachler, M., Nelson, G. and Rosi, S. (2018) Temporary microglia-depletion after cosmic radiation modifies phagocytic activity and prevents cognitive deficits. Sci. Rep. * co-first authors
2. Feng, X., Krukowski, K., Jopson, T. and Rosi S. (2017) Delayed-matching-to-place task in a dry maze to measure spatial working memory in mice. Bio Protoc.
3. Feng, X. and Rosi, S. (2017) Targeting colony stimulating factor 1 receptor to prevent cognitive deficits induced by fractionated whole-brain irradiation. Neural Regen Res.
4. Feng, X., Jopson, T., Paladini, M.S., Liu, S., West, B., Gupta, N. and Rosi, S. (2016) CSF-1R blockade prevents fractionated cranial irradiation induced memory loss. Journal of Neuroinflammation.
5. Feng, X., Szulzewsky, F., Yerevanian A., Chen Z., Heinzmann D., Rasmussen, D.R, Alvarez-Garcia, V., Kim, Y., Wang, B., Tamagno, I., Zhou, H., Li, X., Kettenmann, H., Ransohoff, R.M. and Hambardzumyan, D. (2015) Loss of CX3CR1 increases accumulation of inflammatory monocytes and promote gliomagenesis. Oncotarget.
6. Feng, X., Liu, X., Zhang, W., and Xiao, W. (2011) P53 Directly Suppresses BNIP3 Expression to Protect Against Hypoxia-induced Cell Death. EMBO Journal.
7. Guglielmetti, C., Chou, A., Krukowski, K., Najac, C., Feng, X.,Riparip, L.R., Rosi, S., Chaumeil M.M., (2017) In vivo metabolic imaging of Traumatic Brain Injury. Scientific Reports.
8. Chen, Z., Feng, X., Herting, C.J., Alvares Garcia, V., Nie, K., Pong, W.W., Rasmussen, R., Dwivedi, B., Seby, S., Wolf, S.A., Gutmann, D., and Hambardzumyan, D. (2017) Identity and gene profile of tumor-associated macrophages in glioblastoma. Cancer Research
9. Szulzewsky, F., Pelz, A., Feng, X., Synowitz, M., Markovic, D., Langmann, T., Holtman, I.R., Wang, X., Eggen, B.J.L., Boddeke, H., Hambardzumyan, D., Wolf, S.A. and Ketternmann, H. (2015) Glioma-associated microglia/macrophages display an expression profile different from M1 and M2 polarization and higly express GPNMB and SPP1. PLoS One.
10. Pitter, K.L.,Tamagno, I., Feng, X., Ghosal, K., Amankulor, N., Holland, E.C., and Hambardzumyan, D. (2014) The SHH/Gli pathway is reactivated in reactive glia and drives proliferation in response to neurodegeneration-induced lesions. Glia.
11. Hu, B., Zhang, W., Feng, X., Ji, W., Xie, X., and Xiao, W. (2014) Zebrafish eaf1 Suppresses Foxo3b Expression to Modulate Transcriptional Activity of Gata1 and Spi1 in Primitive Hematopoiesis. Developmental Biology.
12. Pong, W., Walker, J., Wylie, T., Magrini, V., Luo, J., Emnett, R., Choi, J., Cooper, M., Griffith, M.,Griffith, O., Rubin, J., Fuller, G., Piwnica-Worms, D., Feng, X., Hanbardzumyan, D., DiPersio, J., Mardis, J.,and Gutmann, D. (2013) F11R is a Novel Monocyte Prognostic Biomarker for Malignant Glioma. PLOS ONE.
13. Li, M., He, Y., Feng, X., and Huang, J. (2012) Genome-wide stidies of the transcriptional regulation by p53. Biochimica et Biophysica Acta.
14. Wan, X.,Hu, B., Liu, J.,Feng, X., and Xiao, W., (2011) The Essential Role of Mll in Zebrafish Hematopoiesis. Journal of Biological Chemistry.
15. Zhou, J., Feng, X., Ban, B., Liu, J., Wang, Z., and Xiao, W. (2009) The Elongation Factor Ell (Eleven-nineteen Lysine-Rich Leukemia) Acts as a Transcription Factor for Direct Thrombospondin-1 Regulation. Journal of Biological Chemistry.
1 Protocol published
Delayed-matching-to-place Task in a Dry Maze to Measure Spatial Working Memory in Mice
Authors:  Xi Feng, Karen Krukowski, Timothy Jopson and Susanna Rosi, date: 07/05/2017, view: 2800, Q&A: 0
The delayed-matching-to-place (DMP) dry maze test is a variant of DMP water maze (Steele and Morris, 1999; Faizi et al., 2012) which measures spatial working/episodic-like learning and memory that depends on both hippocampal and cortical ...
10 Protocols reviewed
Assessing Prepulse Inhibition of Startle in Mice
Authors:  Christina Ioannidou, Giovanni Marsicano and Arnau Busquets-Garcia, date: 04/05/2018, view: 1361, Q&A: 0
Animal models are an important tool for studying neuropsychiatric disorders. However, a major challenge for researchers working with laboratory rodents is trying to reproduce ‘core’ symptoms of complex human disorders such as schizophrenia. Despite ...
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In vivo Leukemogenesis Model Using Retrovirus Transduction
Authors:  Hiroshi Okuda and Akihiko Yokoyama, date: 12/05/2017, view: 1798, Q&A: 0
Various genetic alterations such as chromosomal translocation cause leukemia. For examples, gene rearrangements of the mixed-lineage leukemia (MLL) gene generate MLL fusion genes, whose products are potent oncogenic drivers in ...
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18 Protocols edited
Zebrafish Embryo Xenograft and Metastasis Assay
Authors:  Ilkka Paatero, Sanni Alve, Silvia Gramolelli, Johanna Ivaska and Päivi M. Ojala, date: 09/20/2018, view: 363, Q&A: 0
Xenograft models, and in particular the mouse xenograft model, where human cancer cells are transplanted into immunocompromised mice, have been used extensively in cancer studies. Although these models have contributed enormously to our ...
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Investigating Neural Stem Cell and Glioma Stem Cell Self-renewal Potential Using Extreme Limiting Dilution Analysis (ELDA)
Authors:  Hong PT Nguyen, Paul M Daniel, Gulay Filiz and Theo Mantamadiotis, date: 09/05/2018, view: 303, Q&A: 0
Glioma stem cells (GSC) grown as neurospheres exhibit similar characteristics to neural stem cells (NSC) grown as neurospheres, including the ability to self-renew and differentiate. GSCs are thought to play a role in cancer initiation and ...
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